A rat model established by simulating genetic–environmental interactions recapitulates human Alzheimer's disease pathology

Acrolein adducts and responding autoantibodies correlate with metabolic disturbance in Alzheimer’s disease

(2023) Monika Renuka Sanotra et al.   Alzheimers Research & Therapy

Amyloid Pathology in the Central Auditory Pathway of 5XFAD Mice Appears First in Auditory Cortex

(2022) Aldis P. Weible et al.   JOURNAL OF ALZHEIMERS DISEASE

Gene–environment interactions in Alzheimer disease: the emerging role of epigenetics

(2022) Lucia Migliore et al.   Nature Reviews Neurology

Alzheimer's disease

(2021) Philip Scheltens et al.   LANCET

Enhancing GABAergic signaling ameliorates aberrant gamma oscillations of olfactory bulb in AD mouse models

(2021) Ming Chen et al.   Molecular Neurodegeneration

White matter hyperintensities and patterns of atrophy in early onset Alzheimer’s disease with causative gene mutations

(2021) Chenhui Mao et al.   CLINICAL NEUROLOGY AND NEUROSURGERY

The heritability of amyloid burden in older adults: the Older Australian Twins Study

(2021) Rebecca Koncz et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Acrolein, an endogenous aldehyde induces Alzheimer's disease-like pathologies in mice: A new sporadic AD animal model

(2021) Chen Chen et al.   PHARMACOLOGICAL RESEARCH

Emerging risk of environmental factors: insight mechanisms of Alzheimer’s diseases

(2020) Md Ataur Rahman et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Leveraging preclinical models for the development of Alzheimer disease therapeutics

(2020) Kimberly Scearce-Levie et al.   NATURE REVIEWS DRUG DISCOVERY

Advance of sporadic Alzheimer's disease animal models

(2019) Lili Zhang et al.   MEDICINAL RESEARCH REVIEWS

The SIGMA rat brain templates and atlases for multimodal MRI data analysis and visualization

(2019) D. A. Barrière et al.   Nature Communications

Immune Response Mechanisms against AAV Vectors in Animal Models

(2019) Ashley T. Martino et al.   Molecular Therapy-Methods & Clinical Development

CSF biomarkers of Alzheimer's disease concord with amyloid-β PET and predict clinical progression: A study of fully automated immunoassays in BioFINDER and ADNI cohorts

(2018) Oskar Hansson et al.   Alzheimers & Dementia

Data-driven models of dominantly-inherited Alzheimer’s disease progression

(2018) Neil P Oxtoby et al.   BRAIN

Spatial patterns of neuroimaging biomarker change in individuals from families with autosomal dominant Alzheimer's disease: a longitudinal study

(2018) Brian A Gordon et al.   LANCET NEUROLOGY

White matter changes in Alzheimer’s disease: a focus on myelin and oligodendrocytes

(2018) Sara E. Nasrabady et al.   Acta Neuropathologica Communications

Internal Consistency Over Time of Subjective Cognitive Decline: Drawing Preclinical Alzheimer’s Disease Trajectories

(2018) Marina Ávila-Villanueva et al.   JOURNAL OF ALZHEIMERS DISEASE

Vagus nerve stimulation: Surgical technique of implantation and revision and related morbidity

(2017) Flavio Giordano et al.   EPILEPSIA

Alterations in Acrolein Metabolism Contribute to Alzheimer’s Disease

(2017) Han-Hsing Tsou et al.   JOURNAL OF ALZHEIMERS DISEASE

Alzheimer’s disease: experimental models and reality

(2016) Eleanor Drummond et al.   ACTA NEUROPATHOLOGICA

Brain atrophy in Alzheimer’s Disease and aging

(2016) Lorenzo Pini et al.   AGEING RESEARCH REVIEWS

Evaluation of dementia by acrolein, amyloid-β and creatinine

(2015) Kazuei Igarashi et al.   CLINICA CHIMICA ACTA

Multimodality Imaging of Alzheimer Disease and Other Neurodegenerative Dementias

(2014) I. M. Nasrallah et al.   JOURNAL OF NUCLEAR MEDICINE

Single App knock-in mouse models of Alzheimer's disease

(2014) Takashi Saito et al.   NATURE NEUROSCIENCE

Treatment effects in multiple cognitive domains in Alzheimer’s disease: a two-year cohort study

(2014) Pearl Behl et al.   Alzheimers Research & Therapy

Brain Microstructure Reveals Early Abnormalities more than Two Years prior to Clinical Progression from Mild Cognitive Impairment to Alzheimer's Disease

(2013) G. Douaud et al.   JOURNAL OF NEUROSCIENCE

Acrolein induces Alzheimer's disease-like pathologies in vitro and in vivo

(2013) Ying-Juan Huang et al.   TOXICOLOGY LETTERS

Oral exposure to acrolein exacerbates atherosclerosis in apoE-null mice

(2011) Sanjay Srivastava et al.   ATHEROSCLEROSIS

Sex differences in grey matter atrophy patterns among AD and aMCI patients: Results from ADNI

(2011) Martha Skup et al.   NEUROIMAGE

Potential Role of Acrolein in Neurodegeneration and in Alzheimers Disease

(2010) Dang Thanh Nam et al.   Current Molecular Pharmacology

Hypothetical model of dynamic biomarkers of the Alzheimer's pathological cascade

(2009) Clifford R Jack et al.   LANCET NEUROLOGY

MRI and CSF biomarkers in normal, MCI, and AD subjects: Predicting future clinical change

(2009) P. Vemuri et al.   NEUROLOGY

Acrolein environmental levels and potential for human exposure

(2008) O Faroon et al.   TOXICOLOGY AND INDUSTRIAL HEALTH