Integrated differential transcriptome maps of Acute Megakaryoblastic Leukemia (AMKL) in children with or without Down Syndrome (DS)

Haematopoietic development and leukaemia in Down syndrome

(2014) Irene Roberts et al.   BRITISH JOURNAL OF HAEMATOLOGY

A quantitative transcriptome reference map of the normal human brain

(2014) Maria Caracausi et al.   NEUROGENETICS

Blast cell deficiency of CD11a as a marker of acute megakaryoblastic leukemia and transient myeloproliferative disease in children with and without Down syndrome

(2013) Heidrun Boztug et al.   CYTOMETRY PART B-CLINICAL CYTOMETRY

Universal tight correlation of codon bias and pool of RNA codons (codonome): The genome is optimized to allow any distribution of gene expression values in the transcriptome from bacteria to humans

(2013) Allison Piovesan et al.   GENOMICS

Overexpression of GATA1 Confers Resistance to Chemotherapy in Acute Megakaryocytic Leukemia

(2013) John Timothy Caldwell et al.   PLoS One

Identification of TRIB1 R107L gain-of-function mutation in human acute megakaryocytic leukemia

(2012) T. Yokoyama et al.   BLOOD

Amplified segment in the ‘Down Syndrome critical region’ on HSA21 shared between Down syndrome and euploid AML-M0 excludes RUNX1, ERG and ETS2

(2012) Claudia Canzonetta et al.   BRITISH JOURNAL OF HAEMATOLOGY

Increased dosage of the chromosome 21 ortholog Dyrk1a promotes megakaryoblastic leukemia in a murine model of Down syndrome

(2012) Sébastien Malinge et al.   JOURNAL OF CLINICAL INVESTIGATION

Trisomy 21-associated defects in human primitive hematopoiesis revealed through induced pluripotent stem cells

(2012) S. T. Chou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Altered hematopoiesis in trisomy 21 as revealed through in vitro differentiation of isogenic human pluripotent cells

(2012) G. A. MacLean et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TRAM (Transcriptome Mapper): database-driven creation and analysis of transcriptome maps from multiple sources

(2011) Luca Lenzi et al.   BMC GENOMICS

Densely Interconnected Transcriptional Circuits Control Cell States in Human Hematopoiesis

(2011) Noa Novershtern et al.   CELL

Neonatal and adult megakaryopoiesis

(2011) Zhi-Jian Liu et al.   CURRENT OPINION IN HEMATOLOGY

Mapping transcription mechanisms from multimodal genomic data

(2010) Hsun-Hsien Chang et al.   BMC BIOINFORMATICS

Hematopoietic differentiation: a coordinated dynamical process towards attractor stable states

(2010) Nadia Felli et al.   BMC Systems Biology

TIM-3 Is a Promising Target to Selectively Kill Acute Myeloid Leukemia Stem Cells

(2010) Yoshikane Kikushige et al.   Cell Stem Cell

Developmental stage-specific interplay of GATA1 and IGF signaling in fetal megakaryopoiesis and leukemogenesis

(2010) J.-H. Klusmann et al.   GENES & DEVELOPMENT

miR-125b-2 is a potential oncomiR on human chromosome 21 in megakaryoblastic leukemia

(2010) J.-H. Klusmann et al.   GENES & DEVELOPMENT

Targeting of histamine producing cells by EGCG: a green dart against inflammation?

(2010) Esther Melgarejo et al.   JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY

Tumour angiogenesis is reduced in the Tc1 mouse model of Down’s syndrome

(2010) Louise E. Reynolds et al.   NATURE

AltAnalyze and DomainGraph: analyzing and visualizing exon expression data

(2010) Dorothea Emig et al.   NUCLEIC ACIDS RESEARCH

Down syndrome: The crucible for treating genomic imbalance

(2009) Julie R Korenberg   GENETICS IN MEDICINE

Molecular genetic analysis of Down syndrome

(2009) David Patterson   HUMAN GENETICS

Regulation of megakaryocyte maturation and platelet formation

(2009) D. BLUTEAU et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Genomic analysis reveals few genetic alterations in pediatric acute myeloid leukemia

(2009) I. Radtke et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular basis of pharmacotherapies for cognition in Down syndrome

(2009) Katheleen J. Gardiner   TRENDS IN PHARMACOLOGICAL SCIENCES

Abnormalities in the myeloid progenitor compartment in Down syndrome fetal liver precede acquisition of GATA1 mutations

(2008) O. Tunstall-Pedoe et al.   BLOOD

Trisomy 21 enhances human fetal erythro-megakaryocytic development

(2008) S. T. Chou et al.   BLOOD

Somatic mutations and germline sequence variants in the expressed tyrosine kinase genes of patients with de novo acute myeloid leukemia

(2008) M. H. Tomasson et al.   BLOOD

Down syndrome and the genes of human chromosome 21: current knowledge and future potentials

(2008) M. Pritchard et al.   CYTOGENETIC AND GENOME RESEARCH