Wnt modulates MCL1 to control cell survival in triple negative breast cancer

Programming cancer cells for high expression levels of Mcl1

(2013) Franziska Ertel et al.   EMBO REPORTS

Mcl-1-dependent activation of Beclin 1 mediates autophagic cell death induced by sorafenib and SC-59 in hepatocellular carcinoma cells

(2013) W-T Tai et al.   Cell Death & Disease

Adjuvant treatments for triple-negative breast cancers

(2012) H. Joensuu et al.   ANNALS OF ONCOLOGY

Autophagy

(2012) Tsung-Chin Lin et al.   Autophagy

Chemical Genomics Identifies Small-Molecule MCL1 Repressors and BCL-xL as a Predictor of MCL1 Dependency

(2012) Guo Wei et al.   CANCER CELL

MYC directs transcription of MCL1 and eIF4E genes to control sensitivity of gastric cancer cells toward HDAC inhibitors

(2012) Wajana L. Labisso et al.   CELL CYCLE

β-Catenin Regulates Hepatic Mitochondrial Function and Energy Balance in Mice

(2012) Nadja Lehwald et al.   GASTROENTEROLOGY

Secreted frizzled-related protein 5 suppresses adipocyte mitochondrial metabolism through WNT inhibition

(2012) Hiroyuki Mori et al.   JOURNAL OF CLINICAL INVESTIGATION

MYC pathway activation in triple-negative breast cancer is synthetic lethal with CDK inhibition

(2012) Dai Horiuchi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Comprehensive molecular portraits of human breast tumours

(2012) Daniel C. Koboldt et al.   NATURE

Anti-apoptotic MCL-1 localizes to the mitochondrial matrix and couples mitochondrial fusion to respiration

(2012) Rhonda M. Perciavalle et al.   NATURE CELL BIOLOGY

Mitochondria: master regulators of danger signalling

(2012) Lorenzo Galluzzi et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Treatment of HER2-positive breast cancer: current status and future perspectives

(2011) Carlos L. Arteaga et al.   Nature Reviews Clinical Oncology

FZD7 has a critical role in cell proliferation in triple negative breast cancer

(2011) L Yang et al.   ONCOGENE

Wnt signaling regulates mitochondrial physiology and insulin sensitivity

(2010) J. C. Yoon et al.   GENES & DEVELOPMENT

Efficacy of Neoadjuvant Cisplatin in Triple-Negative Breast Cancer

(2010) Daniel P. Silver et al.   JOURNAL OF CLINICAL ONCOLOGY

The landscape of somatic copy-number alteration across human cancers

(2010) Rameen Beroukhim et al.   NATURE

Dose-dense treatment for triple-negative breast cancer

(2010) Eitan Amir et al.   Nature Reviews Clinical Oncology

Triple-negative breast cancer--current status and future directions

(2009) O. Gluz et al.   ANNALS OF ONCOLOGY

A Novel Lung Metastasis Signature Links Wnt Signaling with Cancer Cell Self-Renewal and Epithelial-Mesenchymal Transition in Basal-like Breast Cancer

(2009) Theresa A. DiMeo et al.   CANCER RESEARCH

Importing Mitochondrial Proteins: Machineries and Mechanisms

(2009) Agnieszka Chacinska et al.   CELL

Towards an integrated view of Wnt signaling in development

(2009) R. van Amerongen et al.   DEVELOPMENT

Wnt/β-Catenin Signaling: Components, Mechanisms, and Diseases

(2009) Bryan T. MacDonald et al.   DEVELOPMENTAL CELL

Deubiquitinase USP9X stabilizes MCL1 and promotes tumour cell survival

(2009) Martin Schwickart et al.   NATURE

Activated Wnt/ss-catenin signaling in melanoma is associated with decreased proliferation in patient tumors and a murine melanoma model

(2009) A. J. Chien et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A hyperfused mitochondrial state achieved at G1-S regulates cyclin E buildup and entry into S phase

(2009) K. Mitra et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Selective activation mechanisms of Wnt signaling pathways

(2009) Akira Kikuchi et al.   TRENDS IN CELL BIOLOGY