Secreted frizzled-related protein 5 suppresses adipocyte mitochondrial metabolism through WNT inhibition

Pro-Inflammatory wnt5a and Anti-Inflammatory sFRP5 Are Differentially Regulated by Nutritional Factors in Obese Human Subjects

(2012) Dominik M. Schulte et al.   PLoS One

Wnt6, Wnt10a and Wnt10b inhibit adipogenesis and stimulate osteoblastogenesis through a β-catenin-dependent mechanism

(2011) William P. Cawthorn et al.   BONE

Distinct association between aberrant methylation of Wnt inhibitors and genetic alterations in acute myeloid leukaemia

(2011) H-A Hou et al.   BRITISH JOURNAL OF CANCER

TLE3 Is a Dual-Function Transcriptional Coregulator of Adipogenesis

(2011) Claudio J. Villanueva et al.   Cell Metabolism

Secreted Wnt “inhibitors” are not just inhibitors: Regulation of extracellular Wnt by secreted Frizzled-related proteins

(2011) Yusuke Mii et al.   DEVELOPMENT GROWTH & DIFFERENTIATION

Successful Resection of Pancreatic Carcinoma Recurrence in the Remnant Pancreas after a Pancreaticoduodenectomy

(2011) Hiroyuki Kinoshita et al.   HEPATO-GASTROENTEROLOGY

Adipose tissue stem cells meet preadipocyte commitment: going back to the future

(2011) William P. Cawthorn et al.   JOURNAL OF LIPID RESEARCH

Type 2 Diabetes Is Associated with Altered NF-κB DNA Binding Activity, JNK Phosphorylation, and AMPK Phosphorylation in Skeletal Muscle after LPS

(2011) Anne Sofie Andreasen et al.   PLoS One

Adipokines as novel biomarkers and regulators of the metabolic syndrome

(2010) Yingfeng Deng et al.   Annals of the New York Academy of Sciences

Enhanced mitochondrial biogenesis contributes to Wnt induced osteoblastic differentiation of C3H10T1/2 cells

(2010) Jee Hyun An et al.   BONE

Wnt signaling regulates mitochondrial physiology and insulin sensitivity

(2010) J. C. Yoon et al.   GENES & DEVELOPMENT

Secreted frizzled-related protein 1 regulates adipose tissue expansion and is dysregulated in severe obesity

(2010) C Lagathu et al.   INTERNATIONAL JOURNAL OF OBESITY

Sfrp5 Is an Anti-Inflammatory Adipokine That Modulates Metabolic Dysfunction in Obesity

(2010) N. Ouchi et al.   SCIENCE

Mitochondrial (Dys)function in Adipocyte (De)differentiation and Systemic Metabolic Alterations

(2009) Aurélia De Pauw et al.   AMERICAN JOURNAL OF PATHOLOGY

Downregulation of SFRP5 expression and its inverse correlation with those of MMP-7 and MT1-MMP in gastric cancer

(2009) Chenghai Zhao et al.   BMC CANCER

Critical Role for Hypothalamic mTOR Activity in Energy Balance

(2009) Hiroyuki Mori et al.   Cell Metabolism

Secreted Frizzled-related proteins enhance the diffusion of Wnt ligands and expand their signalling range

(2009) Y. Mii et al.   DEVELOPMENT

Epigenetic silencing of SFRP5 is related to malignant phenotype and chemoresistance of ovarian cancer through Wnt signaling pathway

(2009) Her-Young Su et al.   INTERNATIONAL JOURNAL OF CANCER

On the Role of FOX Transcription Factors in Adipocyte Differentiation and Insulin-stimulated Glucose Uptake

(2009) Isabelle Gerin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification and treatment of metabolic complications in pediatric obesity

(2009) Katie Larson Ode et al.   REVIEWS IN ENDOCRINE & METABOLIC DISORDERS

New developments in adipogenesis

(2009) Martina I. Lefterova et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Hypertrophy and/or Hyperplasia: Dynamics of Adipose Tissue Growth

(2009) Junghyo Jo et al.   PLoS Computational Biology

Fat and Beyond: The Diverse Biology of PPARγ

(2008) Peter Tontonoz et al.   Annual Review of Biochemistry

Adipose tissue expandability: the metabolic problems of obesity may arise from the inability to become more obese

(2008) Chong Yew Tan et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Epigenetic inactivation of the secreted frizzled-related protein-5 ( SFRP5 ) gene in human breast cancer is associated with unfavorable prognosis

(2008) Jürgen Veeck et al.   CARCINOGENESIS

Dact1, a Nutritionally Regulated Preadipocyte Gene, Controls Adipogenesis by Coordinating the Wnt/ -Catenin Signaling Network

(2008) C. Lagathu et al.   DIABETES

Wnt4 and Wnt5a promote adipocyte differentiation

(2008) Makoto Nishizuka et al.   FEBS LETTERS

Sfrp1, Sfrp2, and Sfrp5 regulate the Wnt/β-catenin and the planar cell polarity pathways during early trunk formation in mouse

(2008) Wataru Satoh et al.   GENESIS

Beyond Wnt inhibition: new functions of secreted Frizzled-related proteins in development and disease

(2008) P. Bovolenta et al.   JOURNAL OF CELL SCIENCE

New role of bone morphogenetic protein 7 in brown adipogenesis and energy expenditure

(2008) Yu-Hua Tseng et al.   NATURE

Transcriptional Paradigms in Mammalian Mitochondrial Biogenesis and Function

(2008) Richard C. Scarpulla   PHYSIOLOGICAL REVIEWS

It's Not How Fat You Are, It's What You Do with It That Counts

(2008) Samuel Virtue et al.   PLOS BIOLOGY