MYC directs transcription of MCL1 and eIF4E genes to control sensitivity of gastric cancer cells toward HDAC inhibitors

The Class I Hdac Inhibitor Mgcd0103 Induces Cell Cycle Arrest and Apoptosis in Colon Cancer Initiating Cells by Upregulating Dickkopf-1 and Non-Canonical Wnt Signaling

(2015)   Oncotarget

A combination of a ribonucleotide reductase inhibitor and histone deacetylase inhibitors downregulates EGFR and triggers BIM-dependent apoptosis in head and neck cancer

(2015) Roland H. Stauber et al.   Oncotarget

Combining Histone Deacetylase Inhibitor Vorinostat with Aurora Kinase Inhibitors Enhances Lymphoma Cell Killing with Repression of c-Myc, hTERT, and microRNA Levels

(2011) L. Kretzner et al.   CANCER RESEARCH

Cap in hand: Targeting eIF4E

(2011) Peter M. Fischer   CELL CYCLE

Schedule-dependent synergy of histone deacetylase inhibitors with DNA damaging agents in small cell lung cancer

(2011) Victoria L. Luchenko et al.   CELL CYCLE

The role of Bcl-2 and its pro-survival relatives in tumourigenesis and cancer therapy

(2011) P N Kelly et al.   CELL DEATH AND DIFFERENTIATION

Rational therapeutic combinations with histone deacetylase inhibitors for the treatment of cancer

(2011) K Ted Thurn et al.   Future Oncology

A Gene Expression Signature of Acquired Chemoresistance to Cisplatin and Fluorouracil Combination Chemotherapy in Gastric Cancer Patients

(2011) Hark Kyun Kim et al.   PLoS One

c-MYC Suppresses BIN1 to Release Poly(ADP-Ribose) Polymerase 1: A Mechanism by Which Cancer Cells Acquire Cisplatin Resistance

(2011) S. Pyndiah et al.   Science Signaling

Histone Deacetylase (HDAC) 1 and 2 Expression and Chemotherapy in Gastric Cancer

(2010) Kathrin Mutze et al.   ANNALS OF SURGICAL ONCOLOGY

The polycomb group protein BMI1 is a transcriptional target of HDAC inhibitors

(2010) Prashant V. Bommi et al.   CELL CYCLE

Inhibitors of HDACs - Effective Drugs Against Cancer?

(2010) S. Muller et al.   CURRENT CANCER DRUG TARGETS

The Yin and Yang functions of the Myc oncoprotein in cancer development and as targets for therapy

(2010) Lars-Gunnar Larsson et al.   EXPERIMENTAL CELL RESEARCH

The clinical development of histone deacetylase inhibitors as targeted anticancer drugs

(2010) Paul A Marks   EXPERT OPINION ON INVESTIGATIONAL DRUGS

A Simple and Cost-Effective Method to Transfect Small Interfering RNAs Into Pancreatic Cancer Cell Lines Using Polyethylenimine

(2010) Matthias Wirth et al.   PANCREAS

Three-gene predictor of clinical outcome for gastric cancer patients treated with chemotherapy

(2010) H K Kim et al.   PHARMACOGENOMICS JOURNAL

Histone deacetylase (HDAC) inhibitors in recent clinical trials for cancer therapy

(2010) Julia M. Wagner et al.   Clinical Epigenetics

Enhancing the apoptotic and therapeutic effects of HDAC inhibitors

(2009) Ailsa J. Frew et al.   CANCER LETTERS

Regulation of Translation Initiation in Eukaryotes: Mechanisms and Biological Targets

(2009) Nahum Sonenberg et al.   CELL

HDAC2 mediates therapeutic resistance of pancreatic cancer cells via the BH3-only protein NOXA

(2009) P Fritsche et al.   GUT

MYC-Dependent Regulation and Prognostic Role of CIP2A in Gastric Cancer

(2009) Anchit Khanna et al.   JNCI-Journal of the National Cancer Institute

HDAC expression and clinical prognosis in human malignancies

(2008) Wilko Weichert   CANCER LETTERS

Targeting the Eukaryotic Translation Initiation Factor 4E for Cancer Therapy

(2008) J. R. Graff et al.   CANCER RESEARCH

c-Myc and eIF4F Are Components of a Feedforward Loop that Links Transcription and Translation

(2008) C.-J. Lin et al.   CANCER RESEARCH

Myc's broad reach

(2008) M. Eilers et al.   GENES & DEVELOPMENT

Association of patterns of class I histone deacetylase expression with patient prognosis in gastric cancer: a retrospective analysis

(2008) Wilko Weichert et al.   LANCET ONCOLOGY

Downregulation of Mcl-1 potentiates HDACi-mediated apoptosis in leukemic cells

(2008) S Inoue et al.   LEUKEMIA

eIF4E knockdown decreases breast cancer cell growth without activating Akt signaling

(2008) A. Soni et al.   MOLECULAR CANCER THERAPEUTICS

Modelling Myc inhibition as a cancer therapy

(2008) Laura Soucek et al.   NATURE

Chromatin immunoprecipitation (ChIP) coupled to detection by quantitative real-time PCR to study transcription factor binding to DNA in Caenorhabditis elegans

(2008) Arnab Mukhopadhyay et al.   Nature Protocols

The Rpd3/Hda1 family of lysine deacetylases: from bacteria and yeast to mice and men

(2008) Xiang-Jiao Yang et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

MYC and gastric adenocarcinoma carcinogenesis

(2008) Danielle Queiroz Calcagno et al.   WORLD JOURNAL OF GASTROENTEROLOGY