- Home
- Publications
- Publication Search
- Publication Details
Title
Notch signaling: switching an oncogene to a tumor suppressor
Authors
Keywords
-
Journal
BLOOD
Volume 123, Issue 16, Pages 2451-2459
Publisher
American Society of Hematology
Online
2014-03-08
DOI
10.1182/blood-2013-08-355818
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- A Genome-Wide Aberrant RNA Splicing in Patients with Acute Myeloid Leukemia Identifies Novel Potential Disease Markers and Therapeutic Targets
- (2013) Sophia Adamia et al. CLINICAL CANCER RESEARCH
- Notch pathway activation targets AML-initiating cell homeostasis and differentiation
- (2013) Camille Lobry et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Notch activation inhibits AML growth and survival: a potential therapeutic approach
- (2013) Sankaranarayanan Kannan et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Notch signaling in acute promyelocytic leukemia
- (2013) N R Grieselhuber et al. LEUKEMIA
- T cell development requires constraint of the myeloid regulator C/EBP-α by the Notch target and transcriptional repressor Hes1
- (2013) Maria Elena De Obaldia et al. NATURE IMMUNOLOGY
- Genomic and Epigenomic Landscapes of Adult De Novo Acute Myeloid Leukemia
- (2013) NEW ENGLAND JOURNAL OF MEDICINE
- Hematopoietic stem cells: to be or Notch to be
- (2012) A. Bigas et al. BLOOD
- The coding genome of splenic marginal zone lymphoma: activation ofNOTCH2and other pathways regulating marginal zone development
- (2012) Davide Rossi et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Whole-genome sequencing identifies recurrent somaticNOTCH2mutations in splenic marginal zone lymphoma
- (2012) Mark J. Kiel et al. JOURNAL OF EXPERIMENTAL MEDICINE
- NOTCH1 Nuclear Interactome Reveals Key Regulators of Its Transcriptional Activity and Oncogenic Function
- (2012) Ahmad Yatim et al. MOLECULAR CELL
- IDH1(R132H) mutation increases murine haematopoietic progenitors and alters epigenetics
- (2012) Masato Sasaki et al. NATURE
- Genetic inactivation of the polycomb repressive complex 2 in T cell acute lymphoblastic leukemia
- (2012) Panagiotis Ntziachristos et al. NATURE MEDICINE
- Protein O-fucosyltransferase 1 (Pofut1) regulates lymphoid and myeloid homeostasis through modulation of Notch receptor ligand interactions
- (2011) D. Yao et al. BLOOD
- Dual functions of cell-autonomous and non-cell-autonomous ADAM10 activity in granulopoiesis
- (2011) M. Yoda et al. BLOOD
- Deletion of Tet2 in mice leads to dysregulated hematopoietic stem cells and subsequent development of myeloid malignancies
- (2011) Z. Li et al. BLOOD
- TET2 Inactivation Results in Pleiotropic Hematopoietic Abnormalities in Mouse and Is a Recurrent Event during Human Lymphomagenesis
- (2011) Cyril Quivoron et al. CANCER CELL
- Oncometabolite 2-Hydroxyglutarate Is a Competitive Inhibitor of α-Ketoglutarate-Dependent Dioxygenases
- (2011) Wei Xu et al. CANCER CELL
- Tet2 Loss Leads to Increased Hematopoietic Stem Cell Self-Renewal and Myeloid Transformation
- (2011) Kelly Moran-Crusio et al. CANCER CELL
- Epigenetics in Alternative Pre-mRNA Splicing
- (2011) Reini F. Luco et al. CELL
- Notch2 governs the rate of generation of mouse long- and short-term repopulating stem cells
- (2011) Barbara Varnum-Finney et al. JOURNAL OF CLINICAL INVESTIGATION
- Analysis of the chronic lymphocytic leukemia coding genome: role ofNOTCH1mutational activation
- (2011) Giulia Fabbri et al. JOURNAL OF EXPERIMENTAL MEDICINE
- A SIRT1-LSD1 Corepressor Complex Regulates Notch Target Gene Expression and Development
- (2011) Peter Mulligan et al. MOLECULAR CELL
- A novel tumour-suppressor function for the Notch pathway in myeloid leukaemia
- (2011) Apostolos Klinakis et al. NATURE
- Whole-genome sequencing identifies recurrent mutations in chronic lymphocytic leukaemia
- (2011) Xose S. Puente et al. NATURE
- Identification of Novel Targets of CSL-Dependent Notch Signaling in Hematopoiesis
- (2011) Habib Hamidi et al. PLoS One
- Ten-Eleven-Translocation 2 (TET2) negatively regulates homeostasis and differentiation of hematopoietic stem cells in mice
- (2011) M. Ko et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Exome Sequencing of Head and Neck Squamous Cell Carcinoma Reveals Inactivating Mutations in NOTCH1
- (2011) N. Agrawal et al. SCIENCE
- The Mutational Landscape of Head and Neck Squamous Cell Carcinoma
- (2011) N. Stransky et al. SCIENCE
- Notch/Delta4 signaling inhibits human megakaryocytic terminal differentiation
- (2010) S. Poirault-Chassac et al. BLOOD
- Leukemic IDH1 and IDH2 Mutations Result in a Hypermethylation Phenotype, Disrupt TET2 Function, and Impair Hematopoietic Differentiation
- (2010) Maria E. Figueroa et al. CANCER CELL
- Endothelial Cells Are Essential for the Self-Renewal and Repopulation of Notch-Dependent Hematopoietic Stem Cells
- (2010) Jason M. Butler et al. Cell Stem Cell
- Molecular genetics in acute myeloid leukemia
- (2010) Ulrike Bacher et al. CURRENT OPINION IN ONCOLOGY
- Cancer-associated metabolite 2-hydroxyglutarate accumulates in acute myelogenous leukemia with isocitrate dehydrogenase 1 and 2 mutations
- (2010) Stefan Gross et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Notch-mediated expansion of human cord blood progenitor cells capable of rapid myeloid reconstitution
- (2010) Colleen Delaney et al. NATURE MEDICINE
- Early T-cell precursor leukaemia: a subtype of very high-risk acute lymphoblastic leukaemia
- (2009) Elaine Coustan-Smith et al. LANCET ONCOLOGY
- GSK3 is a negative regulator of the transcriptional coactivator MAML1
- (2009) M. Saint Just Ribeiro et al. NUCLEIC ACIDS RESEARCH
- Alterations of the Notch pathway in lung cancer
- (2009) Britta Westhoff et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Notch-dependent control of myelopoiesis is regulated by fucosylation
- (2008) L. Zhou et al. BLOOD
- Defective Notch activation in microenvironment leads to myeloproliferative disease
- (2008) Y.-W. Kim et al. BLOOD
- Notch Signaling Specifies Megakaryocyte Development from Hematopoietic Stem Cells
- (2008) Thomas Mercher et al. Cell Stem Cell
- Canonical Notch Signaling Is Dispensable for the Maintenance of Adult Hematopoietic Stem Cells
- (2008) Ivan Maillard et al. Cell Stem Cell
- Leukemia-associated NOTCH1 alleles are weak tumor initiators but accelerate K-ras–initiated leukemia
- (2008) Mark Y. Chiang et al. JOURNAL OF CLINICAL INVESTIGATION
- Of lineage and legacy: the development of mammalian hematopoietic stem cells
- (2008) Elaine Dzierzak et al. NATURE IMMUNOLOGY
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started