Protein O-fucosyltransferase 1 (Pofut1) regulates lymphoid and myeloid homeostasis through modulation of Notch receptor ligand interactions

O-Fucose Modulates Notch-Controlled Blood Lineage Commitment

(2010) Quanjian Yan et al.   AMERICAN JOURNAL OF PATHOLOGY

Effects of varying Notch1 signal strength on embryogenesis and vasculogenesis in compound mutant heterozygotes

(2010) Changhui Ge et al.   BMC DEVELOPMENTAL BIOLOGY

Endothelial Cells Are Essential for the Self-Renewal and Repopulation of Notch-Dependent Hematopoietic Stem Cells

(2010) Jason M. Butler et al.   Cell Stem Cell

Lunatic Fringe Enhances Competition for Delta-Like Notch Ligands but Does Not Overcome Defective Pre-TCR Signaling during Thymocyte  -Selection In Vivo

(2010) I. Visan et al.   JOURNAL OF IMMUNOLOGY

Fucose-deficient hematopoietic stem cells have decreased self-renewal and aberrant marrow niche occupancy

(2010) Jay Myers et al.   TRANSFUSION

The Canonical Notch Signaling Pathway: Unfolding the Activation Mechanism

(2009) Raphael Kopan et al.   CELL

Manic fringe is not required for embryonic development, and fringe family members do not exhibit redundant functions in the axial skeleton, limb, or hindbrain

(2009) Jennifer L. Moran et al.   DEVELOPMENTAL DYNAMICS

Lunatic and Manic Fringe Cooperatively Enhance Marginal Zone B Cell Precursor Competition for Delta-like 1 in Splenic Endothelial Niches

(2009) Joanne B. Tan et al.   IMMUNITY

Notch-dependent control of myelopoiesis is regulated by fucosylation

(2008) L. Zhou et al.   BLOOD

Defective Notch activation in microenvironment leads to myeloproliferative disease

(2008) Y.-W. Kim et al.   BLOOD

Contributions of chaperone and glycosyltransferase activities of O-fucosyltransferase 1 to Notch signaling

(2008) Tetsuya Okajima et al.   BMC BIOLOGY

In vivo consequences of deleting EGF repeats 8–12 including the ligand binding domain of mouse Notch1

(2008) Changhui Ge et al.   BMC DEVELOPMENTAL BIOLOGY

Bile duct proliferation in Jag1/fringe heterozygous mice identifies candidate modifiers of the alagille syndrome hepatic phenotype

(2008) Matthew J. Ryan et al.   HEPATOLOGY

Roles of Pofut1 andO-Fucose in Mammalian Notch Signaling

(2008) Mark Stahl et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Pofut1 is required for the proper localization of the Notch receptor during mouse development

(2008) Yoshiaki Okamura et al.   MECHANISMS OF DEVELOPMENT

O-fucosylation of muscle agrin determines its ability to cluster acetylcholine receptors

(2008) Mi-Lyang Kim et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

The O-fucose glycan in the ligand-binding domain of Notch1 regulates embryogenesis and T cell development

(2008) C. Ge et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA