T cell development requires constraint of the myeloid regulator C/EBP-α by the Notch target and transcriptional repressor Hes1

C/EBP  is required for development of dendritic cell progenitors

(2013) R. S. Welner et al.   BLOOD

GATA-3 promotes T-cell specification by repressing B-cell potential in pro-T cells in mice

(2013) M. E. Garcia-Ojeda et al.   BLOOD

Architecture of a lymphomyeloid developmental switch controlled by PU.1, Notch and Gata3

(2013) M. M. Del Real et al.   DEVELOPMENT

T Cell Factor 1 Is Required for Group 2 Innate Lymphoid Cell Generation

(2013) Qi Yang et al.   IMMUNITY

Early T-cell progenitors are the major granulocyte precursors in the adult mouse thymus

(2012) M. E. De Obaldia et al.   BLOOD

HES1 opposes a PTEN-dependent check on survival, differentiation, and proliferation of TCR -selected mouse thymocytes

(2012) G. W. Wong et al.   BLOOD

Dynamic Transformations of Genome-wide Epigenetic Marking and Transcriptional Control Establish T Cell Identity

(2012) Jingli A. Zhang et al.   CELL

The earliest thymic T cell progenitors sustain B cell and myeloid lineage potential

(2012) Sidinh Luc et al.   NATURE IMMUNOLOGY

A critical role for TCF-1 in T-lineage specification and differentiation

(2011) Brittany Nicole Weber et al.   NATURE

A novel tumour-suppressor function for the Notch pathway in myeloid leukaemia

(2011) Apostolos Klinakis et al.   NATURE

Lineage-instructive function of C/EBP  in multipotent hematopoietic cells and early thymic progenitors

(2010) A. Wolfler et al.   BLOOD

Fate Mapping Reveals Separate Origins of T Cells and Myeloid Lineages in the Thymus

(2010) Susan M. Schlenner et al.   IMMUNITY

Hes1 Is a Critical but Context-Dependent Mediator of Canonical Notch Signaling in Lymphocyte Development and Transformation

(2010) Agnieszka A. Wendorff et al.   IMMUNITY

Regulation of NOTCH signaling by reciprocal inhibition of HES1 and Deltex 1 and its role in osteosarcoma invasiveness

(2010) P Zhang et al.   ONCOGENE

An Early T Cell Lineage Commitment Checkpoint Dependent on the Transcription Factor Bcl11b

(2010) L. Li et al.   SCIENCE

An Essential Developmental Checkpoint for Production of the T Cell Lineage

(2010) T. Ikawa et al.   SCIENCE

Hes1 immortalizes committed progenitors and plays a role in blast crisis transition in chronic myelogenous leukemia

(2009) F. Nakahara et al.   BLOOD

Single-cell analysis of the common lymphoid progenitor compartment reveals functional and molecular heterogeneity

(2009) R. Mansson et al.   BLOOD

Deletion of Notch1 Converts Pro-T Cells to Dendritic Cells and Promotes Thymic B Cells by Cell-Extrinsic and Cell-Intrinsic Mechanisms

(2008) Thorsten B. Feyerabend et al.   IMMUNITY

Adult T-cell progenitors retain myeloid potential

(2008) Haruka Wada et al.   NATURE

The earliest thymic progenitors for T cells possess myeloid lineage potential

(2008) J. Jeremiah Bell et al.   NATURE

Coordinated regulation of transcription factors through Notch2 is an important mediator of mast cell fate

(2008) M. Sakata-Yanagimoto et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA