Assessing complement blockade in patients with paroxysmal nocturnal hemoglobinuria receiving eculizumab

Dynamics of complement activation in aHUS and how to monitor eculizumab therapy

(2014) M. Noris et al.   BLOOD

Genetic Variants in C5 and Poor Response to Eculizumab

(2014) Jun-ichi Nishimura et al.   NEW ENGLAND JOURNAL OF MEDICINE

Long-term safety and efficacy of sustained eculizumab treatment in patients with paroxysmal nocturnal haemoglobinuria

(2013) Peter Hillmen et al.   BRITISH JOURNAL OF HAEMATOLOGY

Polymorphism of the complement receptor 1 gene correlates with the hematologic response to eculizumab in patients with paroxysmal nocturnal hemoglobinuria

(2013) T. Rondelli et al.   HAEMATOLOGICA

A functional variant in the CFI gene confers a high risk of age-related macular degeneration

(2013) Johannes P H van de Ven et al.   NATURE GENETICS

Predictors of hemoglobin response to eculizumab therapy in paroxysmal nocturnal hemoglobinuria

(2012) Amy E. DeZern et al.   EUROPEAN JOURNAL OF HAEMATOLOGY

Complement Activation and Interleukin Response in Major Abdominal Surgery

(2012) A. L. Kvarnström et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

Long-term treatment with eculizumab in paroxysmal nocturnal hemoglobinuria: sustained efficacy and improved survival

(2011) R. J. Kelly et al.   BLOOD

Management of Paroxysmal Nocturnal Haemoglobinuria: a personal view

(2011) Lucio Luzzatto et al.   BRITISH JOURNAL OF HAEMATOLOGY

Pre-emptive Eculizumab and Plasmapheresis for Renal Transplant in Atypical Hemolytic Uremic Syndrome

(2011) C. Nester et al.   Clinical Journal of the American Society of Nephrology

Common genetic variants in complement genes other than CFH, CD46 and the CFHRs are not associated with aHUS

(2011) Luca Ermini et al.   MOLECULAR IMMUNOLOGY

Prophylactic eculizumab prior to kidney transplantation for atypical hemolytic uremic syndrome

(2011) Marcus Weitz et al.   PEDIATRIC NEPHROLOGY

The management of pregnancy in paroxysmal nocturnal haemoglobinuria on long term eculizumab

(2010) Richard Kelly et al.   BRITISH JOURNAL OF HAEMATOLOGY

Eculizumab prevents intravascular hemolysis in patients with paroxysmal nocturnal hemoglobinuria and unmasks low-level extravascular hemolysis occurring through C3 opsonization

(2010) A. Hill et al.   HAEMATOLOGICA

Pregnancy-Associated Hemolytic Uremic Syndrome Revisited in the Era of Complement Gene Mutations

(2010) F. Fakhouri et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Safety and Long-Term Efficacy of Eculizumab in a Renal Transplant Patient with Recurrent Atypical Hemolytic-Uremic Syndrome

(2009)   AMERICAN JOURNAL OF TRANSPLANTATION

Complement fraction 3 binding on erythrocytes as additional mechanism of disease in paroxysmal nocturnal hemoglobinuria patients treated by eculizumab

(2009) A. M. Risitano et al.   BLOOD

Longitudinal tobit regression: A new approach to analyze outcome variables with floor or ceiling effects

(2009) Jos Twisk et al.   JOURNAL OF CLINICAL EPIDEMIOLOGY