A functional variant in the CFI gene confers a high risk of age-related macular degeneration

Altered Function of Factor I Caused by Amyloid  : Implication for Pathogenesis of Age-Related Macular Degeneration from Drusen

(2014) J. Wang et al.   JOURNAL OF IMMUNOLOGY

Clinical Evaluation of 3 Families With Basal Laminar Drusen Caused by Novel Mutations in the Complement Factor H Gene

(2012) Johannes P. H. van de Ven et al.   ARCHIVES OF OPHTHALMOLOGY

Reducing the Genetic Risk of Age-Related Macular Degeneration With Dietary Antioxidants, Zinc, and ω-3 Fatty Acids

(2011) Lintje Ho   ARCHIVES OF OPHTHALMOLOGY

Common variants near FRK/COL10A1 and VEGFA are associated with advanced age-related macular degeneration

(2011) Yi Yu et al.   HUMAN MOLECULAR GENETICS

Complement factor I in health and disease

(2011) Sara C. Nilsson et al.   MOLECULAR IMMUNOLOGY

A rare penetrant mutation in CFH confers high risk of age-related macular degeneration

(2011) Soumya Raychaudhuri et al.   NATURE GENETICS

Kidney function, albuminuria and age-related macular degeneration in NHANES III

(2011) D. E. Weiner et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Risk Alleles in CFH and ARMS2 Are Independently Associated with Systemic Complement Activation in Age-related Macular Degeneration

(2011) Dzenita Smailhodzic et al.   OPHTHALMOLOGY

Structural basis for complement factor I control and its disease-associated sequence polymorphisms

(2011) P. Roversi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mutations in alternative pathway complement proteins in American patients with atypical hemolytic uremic syndrome

(2010) Tara K. Maga et al.   HUMAN MUTATION

Pregnancy-Associated Hemolytic Uremic Syndrome Revisited in the Era of Complement Gene Mutations

(2010) F. Fakhouri et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Genome-wide association study of advanced age-related macular degeneration identifies a role of the hepatic lipase gene (LIPC)

(2010) B. M. Neale et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genetic variants near TIMP3 and high-density lipoprotein-associated loci influence susceptibility to age-related macular degeneration

(2010) W. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genetic and Functional Dissection of HTRA1 and LOC387715 in Age-Related Macular Degeneration

(2010) Zhenglin Yang et al.   PLoS Genetics

Phospholipase D1 is required for angiogenesis of intersegmental blood vessels in zebrafish

(2009) Xin-Xin I. Zeng et al.   DEVELOPMENTAL BIOLOGY

Genetic profile for five common variants associated with age-related macular degeneration in densely affected families: a novel analytic approach

(2009) Lucia Sobrin et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Mutations in components of complement influence the outcome of Factor I-associated atypical hemolytic uremic syndrome

(2009) Frank Bienaime et al.   KIDNEY INTERNATIONAL

Finding the missing heritability of complex diseases

(2009) Teri A. Manolio et al.   NATURE

Basal Laminar Drusen Caused by Compound Heterozygous Variants in the CFH Gene

(2008) Camiel J.F. Boon et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Variation near complement factor I is associated with risk of advanced AMD

(2008) Jesen A Fagerness et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Genetic, molecular and functional analyses of complement factor I deficiency

(2008) Sara C. Nilsson et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Toll-like Receptor 3 and Geographic Atrophy in Age-Related Macular Degeneration

(2008) Zhenglin Yang et al.   NEW ENGLAND JOURNAL OF MEDICINE