Accumulation of peripheral autoreactive B cells in the absence of functional human regulatory T cells

Cutting Edge: CD25+ Regulatory T Cells Prevent Expansion and Induce Apoptosis of B Cells Specific for Tissue Autoantigens

(2014) I. Ludwig-Portugall et al.   JOURNAL OF IMMUNOLOGY

Defective B cell tolerance in adenosine deaminase deficiency is corrected by gene therapy

(2012) Aisha V. Sauer et al.   JOURNAL OF CLINICAL INVESTIGATION

Immune Dysregulation, Polyendocrinopathy, Enteropathy, X-Linked Syndrome: A Paradigm of Immunodeficiency with Autoimmunity

(2012) Federica Barzaghi et al.   Frontiers in Immunology

Functional type 1 regulatory T cells develop regardless of FOXP3 mutations in patients with IPEX syndrome

(2011) Laura Passerini et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Human Blood CXCR5+CD4+ T Cells Are Counterparts of T Follicular Cells and Contain Specific Subsets that Differentially Support Antibody Secretion

(2011) Rimpei Morita et al.   IMMUNITY

Forkhead box protein 3 (FOXP3) mutations lead to increased TH17 cell numbers and regulatory T-cell instability

(2011) Laura Passerini et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

The PTPN22 allele encoding an R620W variant interferes with the removal of developing autoreactive B cells in humans

(2011) Laurence Menard et al.   JOURNAL OF CLINICAL INVESTIGATION

Follicular regulatory T cells expressing Foxp3 and Bcl-6 suppress germinal center reactions

(2011) Yeonseok Chung et al.   NATURE MEDICINE

Foxp3+ follicular regulatory T cells control the germinal center response

(2011) Michelle A Linterman et al.   NATURE MEDICINE

Helios Expression Is a Marker of T Cell Activation and Proliferation

(2011) Tatiana Akimova et al.   PLoS One

Activation-induced cytidine deaminase (AID) is required for B-cell tolerance in humans

(2011) G. Meyers et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Point mutants of forkhead box P3 that cause immune dysregulation, polyendocrinopathy, enteropathy, X-linked have diverse abilities to reprogram T cells into regulatory T cells

(2010) Alicia N. McMurchy et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

The spectrum of autoantibodies in IPEX syndrome is broad and includes anti-mitochondrial autoantibodies

(2010) Masanobu Tsuda et al.   JOURNAL OF AUTOIMMUNITY

Altered B Cell Development and Anergy in the Absence of Foxp3

(2010) S. M. Leonardo et al.   JOURNAL OF IMMUNOLOGY

Expression of Helios, an Ikaros Transcription Factor Family Member, Differentiates Thymic-Derived from Peripherally Induced Foxp3+ T Regulatory Cells

(2010) A. M. Thornton et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: Regulatory T Cells Directly Suppress B Cells in Systemic Lupus Erythematosus

(2009) N. Iikuni et al.   JOURNAL OF IMMUNOLOGY

Instability of the transcription factor Foxp3 leads to the generation of pathogenic memory T cells in vivo

(2009) Xuyu Zhou et al.   NATURE IMMUNOLOGY

FOXP3 Forkhead Domain Mutation and Regulatory T Cells in the IPEX Syndrome

(2009) Eva d'Hennezel et al.   NEW ENGLAND JOURNAL OF MEDICINE

IRAK-4- and MyD88-Dependent Pathways Are Essential for the Removal of Developing Autoreactive B Cells in Humans

(2008) Isabelle Isnardi et al.   IMMUNITY

Clinical and molecular profile of a new series of patients with immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome: Inconsistent correlation between forkhead box protein 3 expression and disease severity

(2008) Eleonora Gambineri et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Autoantibody production in lpr/lpr gld/gld mice reflects accumulation of CD4+ effector cells that are resistant to regulatory T cell activity

(2008) Brian D. Hondowicz et al.   JOURNAL OF AUTOIMMUNITY