Activation-induced cytidine deaminase (AID) is required for B-cell tolerance in humans

Activation-induced cytidine deaminase mediates central tolerance in B cells

(2011) M. Kuraoka et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Complement receptor 2/CD21- human naive B cells contain mostly autoreactive unresponsive clones

(2010) I. Isnardi et al.   BLOOD

Somatic hypermutation as a generator of antinuclear antibodies in a murine model of systemic autoimmunity

(2010) Wenzhong Guo et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Genome-wide erasure of DNA methylation in mouse primordial germ cells is affected by AID deficiency

(2010) Christian Popp et al.   NATURE

AID constrains germinal center size by rendering B cells susceptible to apoptosis

(2009) A. Zaheen et al.   BLOOD

Deficiency in activation-induced cytidine deaminase promotes systemic autoimmunity inlprmice on a C57BL/6 background

(2009) L. Chen et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Activation-Induced Cytidine Deaminase Expression and Activity in the Absence of Germinal Centers: Insights into Hyper-IgM Syndrome

(2009) M. Kuraoka et al.   JOURNAL OF IMMUNOLOGY

Reprogramming towards pluripotency requires AID-dependent DNA demethylation

(2009) Nidhi Bhutani et al.   NATURE

B-cell tolerance checkpoints in health and autoimmunity

(2008) Eric Meffre et al.   CURRENT OPINION IN IMMUNOLOGY

IRAK-4- and MyD88-Dependent Pathways Are Essential for the Removal of Developing Autoreactive B Cells in Humans

(2008) Isabelle Isnardi et al.   IMMUNITY

Commensal DNA Limits Regulatory T Cell Conversion and Is a Natural Adjuvant of Intestinal Immune Responses

(2008) Jason A. Hall et al.   IMMUNITY

Activation-Induced Cytidine Deaminase Deficiency Causes Organ-Specific Autoimmune Disease

(2008) Koji Hase et al.   PLoS One