AU-rich RNA binding proteins in hematopoiesis and leukemogenesis

The RNA-binding protein HuR stabilizes survivin mRNA in human oesophageal epithelial cells

(2011) James M. Donahue et al.   BIOCHEMICAL JOURNAL

ATM regulates a DNA damage response posttranscriptional RNA operon in lymphocytes

(2011) K. Mazan-Mamczarz et al.   BLOOD

Rb and nucleolin antagonize in controlling human CD34 gene expression

(2011) Edgar Grinstein et al.   CELLULAR SIGNALLING

Deletion of Tristetraprolin Caused Spontaneous Reactive Granulopoiesis by a Non-Cell-Autonomous Mechanism Without Disturbing Long-Term Hematopoietic Stem Cell Quiescence

(2011) I. M. Kaplan et al.   JOURNAL OF IMMUNOLOGY

DIGE-based proteomic analysis identifies nucleophosmin/B23 and nucleolin C23 as over-expressed proteins in relapsed/refractory acute leukemia

(2011) Jianda Hu et al.   LEUKEMIA RESEARCH

HuR-Mediated Control of C/EBP  mRNA Stability and Translation in ALK-Positive Anaplastic Large Cell Lymphomas

(2011) J. Bergalet et al.   MOLECULAR CANCER RESEARCH

The ATM Kinase Induces MicroRNA Biogenesis in the DNA Damage Response

(2011) Xinna Zhang et al.   MOLECULAR CELL

Integrative Regulatory Mapping Indicates that the RNA-Binding Protein HuR Couples Pre-mRNA Processing and mRNA Stability

(2011) Neelanjan Mukherjee et al.   MOLECULAR CELL

Transcriptome-wide Analysis of Regulatory Interactions of the RNA-Binding Protein HuR

(2011) Svetlana Lebedeva et al.   MOLECULAR CELL

Initial genome sequencing and analysis of multiple myeloma

(2011) Michael A. Chapman et al.   NATURE

AUF1 is involved in splenic follicular B cell maintenance

(2010) Navid Sadri et al.   BMC IMMUNOLOGY

The DLEU2/miR-15a/16-1 Cluster Controls B Cell Proliferation and Its Deletion Leads to Chronic Lymphocytic Leukemia

(2010) Ulf Klein et al.   CANCER CELL

Post-transcriptional control during chronic inflammation and cancer: a focus on AU-rich elements

(2010) Khalid S. A. Khabar   CELLULAR AND MOLECULAR LIFE SCIENCES

Stat5 is indispensable for the maintenance ofbcr/abl-positive leukaemia

(2010) Andrea Hoelbl et al.   EMBO Molecular Medicine

Notch Signaling in the Immune System

(2010) Freddy Radtke et al.   IMMUNITY

FasL Expression in Activated T Lymphocytes Involves HuR-mediated Stabilization

(2010) Gillian L. Drury et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Loss of Repression of HuR Translation by miR-16 May Be Responsible for the Elevation of HuR in Human Breast Carcinoma

(2010) Fang Xu et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

ZFP36L1 Negatively Regulates Erythroid Differentiation of CD34+ Hematopoietic Stem Cells by Interfering with the Stat5b Pathway

(2010) Tatiana Vignudelli et al.   MOLECULAR BIOLOGY OF THE CELL

Sequence signatures and mRNA concentration can explain two-thirds of protein abundance variation in a human cell line

(2010) Christine Vogel et al.   Molecular Systems Biology

Deletion of the RNA-binding proteins ZFP36L1 and ZFP36L2 leads to perturbed thymic development and T lymphoblastic leukemia

(2010) Daniel J Hodson et al.   NATURE IMMUNOLOGY

AREsite: a database for the comprehensive investigation of AU-rich elements

(2010) A. R. Gruber et al.   NUCLEIC ACIDS RESEARCH

An extended set of PRDM1/BLIMP1 target genes links binding motif type to dynamic repression

(2010) Gina M. Doody et al.   NUCLEIC ACIDS RESEARCH

A novel concept in antiangiogenic and antitumoral therapy: multitarget destabilization of short-lived mRNAs by the zinc finger protein ZFP36L1

(2010) S Planel et al.   ONCOGENE

RNA-binding protein HuR mediates cytoprotection through stimulation of XIAP translation

(2010) D Durie et al.   ONCOGENE

Phosphorylation of Human Tristetraprolin in Response to Its Interaction with the Cbl Interacting Protein CIN85

(2010) Vishram P. Kedar et al.   PLoS One

Surface Expressed Nucleolin Is Constantly Induced in Tumor Cells to Mediate Calcium-Dependent Ligand Internalization

(2010) Ara G. Hovanessian et al.   PLoS One

MiR-34a attenuates paclitaxel-resistance of hormone-refractory prostate cancer PC3 cells through direct and indirect mechanisms

(2010) Keitaro Kojima et al.   PROSTATE

MicroRNA-125a represses cell growth by targeting HuR in breast cancer

(2010) Xun Guo et al.   RNA Biology

Overexpression of nucleolin in engrafted acute myelogenous leukemia cells

(2009) Sebastiano Gattoni-Celli et al.   AMERICAN JOURNAL OF HEMATOLOGY

Integrated biochemical and computational approach identifies BCL6 direct target genes controlling multiple pathways in normal germinal center B cells

(2009) K. Basso et al.   BLOOD

The BCL6 transcriptional program features repression of multiple oncogenes in primary B cells and is deregulated in DLBCL

(2009) W. Ci et al.   BLOOD

Targeted disruption of Zfp36l2, encoding a CCCH tandem zinc finger RNA-binding protein, results in defective hematopoiesis

(2009) D. J. Stumpo et al.   BLOOD

The RNA-binding protein HuR regulates GATA3 mRNA stability in human breast cancer cell lines

(2009) Lauren A. Licata et al.   BREAST CANCER RESEARCH AND TREATMENT

The mRNA-Destabilizing Protein Tristetraprolin Is Suppressed in Many Cancers, Altering Tumorigenic Phenotypes and Patient Prognosis

(2009) S. E. Brennan et al.   CANCER RESEARCH

LPS induces KH-type splicing regulatory protein-dependent processing of microRNA-155 precursors in macrophages

(2009) Tina Ruggiero et al.   FASEB JOURNAL

HuR recruits let-7/RISC to repress c-Myc expression

(2009) H. H. Kim et al.   GENES & DEVELOPMENT

Tristetraprolin Impairs NF-κB/p65 Nuclear Translocation

(2009) Yvonne M. Schichl et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

RNA-destabilizing Factor Tristetraprolin Negatively Regulates NF-κB Signaling

(2009) Jian Liang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification and Characterization of Nucleolin as a c-mycG-quadruplex-binding Protein

(2009) Verónica González et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nucleophosmin and Nucleolin Regulate K-Ras Plasma Membrane Interactions and MAPK Signal Transduction

(2009) Kerry L. Inder et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

TIS11 Family Proteins and Their Roles in Posttranscriptional Gene Regulation

(2009) Maria Baou et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Essential role of the RNA-binding protein HuR in progenitor cell survival in mice

(2009) Mallika Ghosh et al.   JOURNAL OF CLINICAL INVESTIGATION

AUF1 and HuR Proteins Stabilize Interleukin-8 mRNA in Human Saliva

(2009) V. Palanisamy et al.   JOURNAL OF DENTAL RESEARCH

Control of Thymic T Cell Maturation, Deletion and Egress by the RNA-Binding Protein HuR

(2009) O. Papadaki et al.   JOURNAL OF IMMUNOLOGY

Regulation of Bcl-2 Expression by HuR in HL60 Leukemia Cells and A431 Carcinoma Cells

(2009) D. Ishimaru et al.   MOLECULAR CANCER RESEARCH

The RNA-binding protein KSRP promotes the biogenesis of a subset of microRNAs

(2009) Michele Trabucchi et al.   NATURE

Posttranscriptional gene regulation by RNA-binding proteins during oxidative stress: implications for cellular senescence

(2008) Kotb Abdelmohsen et al.   BIOLOGICAL CHEMISTRY

The role of NF-κB in lymphoid malignancies

(2008) Graham Packham   BRITISH JOURNAL OF HAEMATOLOGY

RNA-binding proteins and post-transcriptional gene regulation

(2008) Tina Glisovic et al.   FEBS LETTERS

The RNA-stabilizing Protein HuR Regulates the Expression of ζ Chain of the Human T Cell Receptor-associated CD3 Complex

(2008) Vaishali R. Moulton et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Decoding ARE-mediated decay: is microRNA part of the equation?

(2008) Christopher von Roretz et al.   JOURNAL OF CELL BIOLOGY

Involvement of Tis11b, an AU-rich binding protein, in induction of apoptosis by rituximab in B cell chronic lymphocytic leukemia cells

(2008) M Baou et al.   LEUKEMIA

Targeted suppression of MCT-1 attenuates the malignant phenotype through a translational mechanism

(2008) Krystyna Mazan-Mamczarz et al.   LEUKEMIA RESEARCH

Stability of Eukaryotic Translation Initiation Factor 4E mRNA Is Regulated by HuR, and This Activity Is Dysregulated in Cancer

(2008) I. Topisirovic et al.   MOLECULAR AND CELLULAR BIOLOGY

MiR-15a and miR-16-1 cluster functions in human leukemia

(2008) George A. Calin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA