ZFP36L1 Negatively Regulates Erythroid Differentiation of CD34+ Hematopoietic Stem Cells by Interfering with the Stat5b Pathway

The Vitamin D3/Hox-A10 Pathway Supports MafB Function during the Monocyte Differentiation of Human CD34+ Hemopoietic Progenitors

(2014) C. Gemelli et al.   JOURNAL OF IMMUNOLOGY

Targeted disruption of Zfp36l2, encoding a CCCH tandem zinc finger RNA-binding protein, results in defective hematopoiesis

(2009) D. J. Stumpo et al.   BLOOD

Phospho-STAT5 and phospho-Akt expression in chronic myeloproliferative neoplasms

(2009) Lizz F. Grimwade et al.   BRITISH JOURNAL OF HAEMATOLOGY

IFN Regulatory Factor 8 Sensitizes Soft Tissue Sarcoma Cells to Death Receptor-Initiated Apoptosis via Repression of FLICE-like Protein Expression

(2009) D. Yang et al.   CANCER RESEARCH

The mRNA-Destabilizing Protein Tristetraprolin Is Suppressed in Many Cancers, Altering Tumorigenic Phenotypes and Patient Prognosis

(2009) S. E. Brennan et al.   CANCER RESEARCH

The Interferon Consensus Sequence Binding Protein (ICSBP/IRF8) Activates Transcription of theFANCFGene during Myeloid Differentiation

(2009) Gurveen Saberwal et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Acute Lymphoblastic Leukemia-associated JAK2 L611S Mutant Induces Tumorigenesis in Nude Mice

(2009) Megumi Funakoshi-Tago et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Tristetraprolin Is Required for Full Anti-Inflammatory Response of Murine Macrophages to IL-10

(2009) B. Schaljo et al.   JOURNAL OF IMMUNOLOGY

Control of mRNA decay by phosphorylation of tristetraprolin

(2008) Heike Sandler et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Myeloproliferative disorders

(2008) R. L. Levine et al.   BLOOD

Stat5 activation enables erythropoiesis in the absence of EpoR and Jak2

(2008) F. Grebien et al.   BLOOD

Single-Cell Profiling Identifies Aberrant STAT5 Activation in Myeloid Malignancies with Specific Clinical and Biologic Correlates

(2008) Nikesh Kotecha et al.   CANCER CELL

Efficacy of TG101348, a Selective JAK2 Inhibitor, in Treatment of a Murine Model of JAK2V617F-Induced Polycythemia Vera

(2008) Gerlinde Wernig et al.   CANCER CELL

Tristetraprolin Down-regulates Interleukin-8 and Vascular Endothelial Growth Factor in Malignant Glioma Cells

(2008) E. Suswam et al.   CANCER RESEARCH

The Signal Transducer STAT5 Inhibits Plasmacytoid Dendritic Cell Development by Suppressing Transcription Factor IRF8

(2008) Eiji Esashi et al.   IMMUNITY

Differential expression of IRF8 in subsets of macrophages and dendritic cells and effects of IRF8 deficiency on splenic B cell and macrophage compartments

(2008) Chen-Feng Qi et al.   IMMUNOLOGIC RESEARCH

IRF8 regulates myeloid and B lymphoid lineage diversification

(2008) Hongsheng Wang et al.   IMMUNOLOGIC RESEARCH

Effects of the JAK2 Inhibitor, AZ960, on Pim/BAD/BCL-xL Survival Signaling in the Human JAK2 V617F Cell Line SET-2

(2008) Joseph M. Gozgit et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Jak2/Stat5 Signaling in Mammogenesis, Breast Cancer Initiation and Progression

(2008) Kay-Uwe Wagner et al.   JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA

In vivo identification of novel STAT5 target genes

(2008) B. Basham et al.   NUCLEIC ACIDS RESEARCH

Identification of TTP mRNA targets in human dendritic cells reveals TTP as a critical regulator of dendritic cell maturation

(2008) J. Emmons et al.   RNA

Downregulation of Signal Transducer and Activator of Transcription 5 (STAT5) in CD34+Cells Promotes Megakaryocytic Development, Whereas Activation of STAT5 Drives Erythropoiesis

(2008) Sandra G. Olthof et al.   STEM CELLS