Allelic methylation levels of the noncoding VTRNA2-1 located on chromosome 5q31.1 predict outcome in AML

Uncoupling of GTP hydrolysis from eIF6 release on the ribosome causes Shwachman-Diamond syndrome

(2011) A. J. Finch et al.   GENES & DEVELOPMENT

Clinical effect of increasing doses of lenalidomide in high-risk myelodysplastic syndrome and acute myeloid leukemia with chromosome 5 abnormalities

(2011) L. Mollgard et al.   HAEMATOLOGICA

Precursor miR-886, a novel noncoding RNA repressed in cancer, associates with PKR and modulates its activity

(2011) K. Lee et al.   RNA

DNA methylation patterns associate with genetic and gene expression variation in HapMap cell lines

(2011) Jordana T Bell et al.   GENOME BIOLOGY

Acquired mutations in the genes encoding IDH1 and IDH2 both are recurrent aberrations in acute myeloid leukemia: prevalence and prognostic value

(2010) S. Abbas et al.   BLOOD

Haploinsufficiency of Apc leads to ineffective hematopoiesis

(2010) J. Wang et al.   BLOOD

Ribosomopathies: human disorders of ribosome dysfunction

(2010) A. Narla et al.   BLOOD

Inhibition of RNA-dependent protein kinase (PKR) leads to cancer cell death and increases chemosensitivity

(2010) Abujiang Pataer et al.   CANCER BIOLOGY & THERAPY

Defining the RNA polymerase III transcriptome: Genome-wide localization of the RNA polymerase III transcription machinery in human cells

(2010) D. Canella et al.   GENOME RESEARCH

MicroRNA miR-886-5p inhibits apoptosis by down-regulating Bax expression in human cervical carcinoma cells

(2010) Jing-Hua Li et al.   GYNECOLOGIC ONCOLOGY

Identification of Patients With Acute Myeloblastic Leukemia Who Benefit From the Addition of Gemtuzumab Ozogamicin: Results of the MRC AML15 Trial

(2010) Alan K. Burnett et al.   JOURNAL OF CLINICAL ONCOLOGY

Multiple forms of PKR present in the nuclei of acute leukemia cells represent an active kinase that is responsive to stress

(2010) W L Blalock et al.   LEUKEMIA

Impact of adjunct cytogenetic abnormalities for prognostic stratification in patients with myelodysplastic syndrome and deletion 5q

(2010) M Mallo et al.   LEUKEMIA

The DNA demethylating agent 5-aza-2′-deoxycytidine induces expression of NY-ESO-1 and other cancer/testis antigens in myeloid leukemia cells

(2010) Maika Almstedt et al.   LEUKEMIA RESEARCH

DNMT3AMutations in Acute Myeloid Leukemia

(2010) Timothy J. Ley et al.   NEW ENGLAND JOURNAL OF MEDICINE

Equitoxic Doses of 5-Azacytidine and 5-Aza-2′Deoxycytidine Induce Diverse Immediate and Overlapping Heritable Changes in the Transcriptome

(2010) Xiangning Qiu et al.   PLoS One

MiR-886-3p Down Regulates CXCL12 (SDF1) Expression in Human Marrow Stromal Cells

(2010) Manoj M. Pillai et al.   PLoS One

Integrative Analysis of the Caenorhabditis elegans Genome by the modENCODE Project

(2010) M. B. Gerstein et al.   SCIENCE

Quantitative DNA methylation predicts survival in adult acute myeloid leukemia

(2009) L. Bullinger et al.   BLOOD

Progressive Chromatin Repression and Promoter Methylation of CTNNA1 Associated with Advanced Myeloid Malignancies

(2009) Y. Ye et al.   CANCER RESEARCH

PKR activity is required for acute leukemic cell maintenance and growth: A role for PKR-mediated phosphatase activity to regulate GSK-3 phosphorylation

(2009) William L. Blalock et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Epstein–Barr Virus-Induced Expression of a Novel Human Vault RNA

(2009) Constanze Nandy et al.   JOURNAL OF MOLECULAR BIOLOGY

Evolution of Vault RNAs

(2009) P. F. Stadler et al.   MOLECULAR BIOLOGY AND EVOLUTION

The non-coding RNA of the multidrug resistance-linked vault particle encodes multiple regulatory small RNAs

(2009) Helena Persson et al.   NATURE CELL BIOLOGY

Identification of miR-145 and miR-146a as mediators of the 5q– syndrome phenotype

(2009) Daniel T Starczynowski et al.   NATURE MEDICINE

Non-imprinted allele-specific DNA methylation on human autosomes

(2009) Yingying Zhang et al.   GENOME BIOLOGY

Telomere maintenance and human bone marrow failure

(2008) R. T. Calado et al.   BLOOD

Vaults and the major vault protein: Novel roles in signal pathway regulation and immunity

(2008) W. Berger et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Identification of RPS14 as a 5q- syndrome gene by RNA interference screen

(2008) Benjamin L. Ebert et al.   NATURE

Sensitive Melting Analysis after Real Time- Methylation Specific PCR (SMART-MSP): high-throughput and probe-free quantitative DNA methylation detection

(2008) L. S. Kristensen et al.   NUCLEIC ACIDS RESEARCH