Multiple forms of PKR present in the nuclei of acute leukemia cells represent an active kinase that is responsive to stress

Inhibition of RNA-dependent protein kinase (PKR) leads to cancer cell death and increases chemosensitivity

(2010) Abujiang Pataer et al.   CANCER BIOLOGY & THERAPY

Double-Stranded RNA-Dependent Protein Kinase Links Pathogen Sensing with Stress and Metabolic Homeostasis

(2010) Takahisa Nakamura et al.   CELL

New Cdc2 Tyr 4 phosphorylation by dsRNA-activated protein kinase triggers Cdc2 polyubiquitination and G2 arrest under genotoxic stresses

(2010) Cheol-Hee Yoon et al.   EMBO REPORTS

PKR activity is required for acute leukemic cell maintenance and growth: A role for PKR-mediated phosphatase activity to regulate GSK-3 phosphorylation

(2009) William L. Blalock et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Neuronal Phosphorylated RNA-Dependent Protein Kinase in Creutzfeldt-Jakob Disease

(2009) Claire Paquet et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

PTEN inhibits BMI1 function independently of its phosphatase activity

(2009) Catherine Fan et al.   Molecular Cancer

Tumor Suppression by PTEN Requires the Activation of the PKR-eIF2  Phosphorylation Pathway

(2009) Z. Mounir et al.   Science Signaling

An Antiviral Response Directed by PKR Phosphorylation of the RNA Helicase A

(2009) Anthony J. Sadler et al.   PLoS Pathogens

Inhibition of activation of dsRNA-dependent protein kinase and tumour growth inhibition

(2008) Helen L. Eley et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

The nuclear affairs of PTEN

(2008) S. M. Planchon et al.   JOURNAL OF CELL SCIENCE

PKR is activated in MDS patients and its subcellular localization depends on disease severity

(2008) M Y Follo et al.   LEUKEMIA

A quantitative atlas of mitotic phosphorylation

(2008) N. Dephoure et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA