Effects of copper on CHO cells: Cellular requirements and product quality considerations

Effects of copper on CHO cells: Insights from gene expression analyses

(2014) Inn H. Yuk et al.   BIOTECHNOLOGY PROGRESS

Chinese hamster ovary K1 host cell enables stable cell line development for antibody molecules which are difficult to express in DUXB11-derived dihydrofolate reductase deficient host cell

(2013) Zhilan Hu et al.   BIOTECHNOLOGY PROGRESS

Bioavailable copper modulates oxidative phosphorylation and growth of tumors

(2013) S. Ishida et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Complex Physiology and Compound Stress Responses during Fermentation of Alkali-Pretreated Corn Stover Hydrolysate by an Escherichia coli Ethanologen

(2012) Michael S. Schwalbach et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Probing of C-terminal lysine variation in a recombinant monoclonal antibody production using Chinese hamster ovary cells with chemically defined media

(2012) Jun Luo et al.   BIOTECHNOLOGY AND BIOENGINEERING

Automated dynamic fed-batch process and media optimization for high productivity cell culture process development

(2012) Franklin Lu et al.   BIOTECHNOLOGY AND BIOENGINEERING

Estimation of raw material performance in mammalian cell culture using near infrared spectra combined with chemometrics approaches

(2012) Hae Woo Lee et al.   BIOTECHNOLOGY PROGRESS

Advanced microscale bioreactor system: a representative scale-down model for bench-top bioreactors

(2012) Wei-Ting Hsu et al.   CYTOTECHNOLOGY

Multivariate analysis of cell culture bioprocess data—Lactate consumption as process indicator

(2012) Huong Le et al.   JOURNAL OF BIOTECHNOLOGY

Characterization of the basic charge variants of a human IgG1

(2012) Timothy Kaschak et al.   mAbs

Chromatographic analysis of the acidic and basic species of recombinant monoclonal antibodies

(2012) Yi Du et al.   mAbs

Lactate metabolism shift in CHO cell culture: the role of mitochondrial oxidative activity

(2012) Francesca Zagari et al.   New Biotechnology

Modulation of antibody galactosylation through feeding of uridine, manganese chloride, and galactose

(2011) Michael J. Gramer et al.   BIOTECHNOLOGY AND BIOENGINEERING

Comparative metabolite analysis to understand lactate metabolism shift in Chinese hamster ovary cell culture process

(2011) Jun Luo et al.   BIOTECHNOLOGY AND BIOENGINEERING

Controlling glycation of recombinant antibody in fed-batch cell cultures

(2011) Inn H. Yuk et al.   BIOTECHNOLOGY AND BIOENGINEERING

Overcoming challenges in WAVE bioreactors without feedback controls for pH and dissolved oxygen

(2011) Inn H. Yuk et al.   BIOTECHNOLOGY PROGRESS

Cell culture and gene transcription effects of copper sulfate on Chinese hamster ovary cells

(2011) Yueming Qian et al.   BIOTECHNOLOGY PROGRESS

The genomic sequence of the Chinese hamster ovary (CHO)-K1 cell line

(2011) Xun Xu et al.   NATURE BIOTECHNOLOGY

Mining manufacturing data for discovery of high productivity process characteristics

(2010) Salim Charaniya et al.   JOURNAL OF BIOTECHNOLOGY

Peptidylgycine α-amidating monooxygenase and copper: A gene-nutrient interaction critical to nervous system function

(2010) Danielle Bousquet-Moore et al.   JOURNAL OF NEUROSCIENCE RESEARCH

The Control of the Metabolic Switch in Cancers by Oncogenes and Tumor Suppressor Genes

(2010) A. J. Levine et al.   SCIENCE

Optimal and consistent protein glycosylation in mammalian cell culture

(2009) P. Hossler et al.   GLYCOBIOLOGY

On-Line CE−LIF−MS Technology for the Direct Characterization of N-Linked Glycans from Therapeutic Antibodies

(2008) Lynn A. Gennaro et al.   ANALYTICAL CHEMISTRY

Mechanisms for copper acquisition, distribution and regulation

(2008) Byung-Eun Kim et al.   Nature Chemical Biology

Effect of Copper Sulfate on Performance of a Serum-Free CHO Cell Culture Process and the Level of Free Thiol in the Recombinant Antibody Expressed

(2005) Wendy B. Chaderjian et al.   BIOTECHNOLOGY PROGRESS