Model-based process development for the purification of a modified human growth hormone using multimodal chromatography

Using high throughput screening to define virus clearance by chromatography resins

(2013) Lisa Connell-Crowley et al.   BIOTECHNOLOGY AND BIOENGINEERING

Methods development in multimodal chromatography with mobile phase modifiers using the steric mass action model

(2013) Hanne Sophie Karkov et al.   JOURNAL OF CHROMATOGRAPHY A

Evaluating antibody monomer separation from associated aggregates using mixed-mode chromatography

(2013) Dong Gao et al.   JOURNAL OF CHROMATOGRAPHY A

Multi-dimensional fractionation and characterization of crude protein mixtures: Toward establishment of a database of protein purification process development parameters

(2012) Beckley K. Nfor et al.   BIOTECHNOLOGY AND BIOENGINEERING

Multimodal chromatography: An efficient tool in downstream processing of proteins

(2012) Kristian Kallberg et al.   Biotechnology Journal

Determination of parameters for the steric mass action model—A comparison between two approaches

(2012) A. Osberghaus et al.   JOURNAL OF CHROMATOGRAPHY A

Mobile phase modifier effects in multimodal cation exchange chromatography

(2011) Melissa A. Holstein et al.   BIOTECHNOLOGY AND BIOENGINEERING

Model-Based Process Challenge of an Industrial Ion-Exchange Chromatography Step

(2011) K. Westerberg et al.   CHEMICAL ENGINEERING & TECHNOLOGY

Evaluation of selectivity in multimodal anion exchange systems: A priori prediction of protein retention and examination of mobile phase modifier effects

(2011) Ying Hou et al.   JOURNAL OF CHROMATOGRAPHY A

Downstream bioprocessing: recent advances and future promise

(2011) Steven M Cramer et al.   Current Opinion in Chemical Engineering

Application of mixed mode resins for the purification of antibodies

(2010) Agnes Voitl et al.   JOURNAL OF CHROMATOGRAPHY A

High-throughput isotherm determination and thermodynamic modeling of protein adsorption on mixed mode adsorbents

(2010) Beckley K. Nfor et al.   JOURNAL OF CHROMATOGRAPHY A

Determining Critical Process Parameters and Process Robustness in Preparative Chromatography - A Model-Based Approach

(2009) M. Degerman et al.   CHEMICAL ENGINEERING & TECHNOLOGY

IgG Aggregate Removal by Charged-Hydrophobic Mixed Mode Chromatography

(2009) Pete Gagnon   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

The distinctive separation attributes of mixed-mode resins and their application in monoclonal antibody downstream purification process

(2009) Jie Chen et al.   JOURNAL OF CHROMATOGRAPHY A

A Review of the Thermodynamics of Protein Association to Ligands, Protein Adsorption, and Adsorption Isotherms

(2008) J. M. Mollerup   CHEMICAL ENGINEERING & TECHNOLOGY