Multimodal chromatography: An efficient tool in downstream processing of proteins

Probing multimodal ligand binding regions on ubiquitin using nuclear magnetic resonance, chromatography, and molecular dynamics simulations

(2012) Melissa A. Holstein et al.   JOURNAL OF CHROMATOGRAPHY A

Plasmid DNA partitioning and separation using poly(ethylene glycol)/poly(acrylate)/salt aqueous two-phase systems

(2012) Hans-Olof Johansson et al.   JOURNAL OF CHROMATOGRAPHY A

A synthetic Protein G adsorbent based on the multi-component Ugi reaction for the purification of mammalian immunoglobulins

(2012) Jianing Qian et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Restricted access boronate affinity porous monolith as a protein A mimetic for the specific capture of immunoglobulin G

(2012) Yunchun Liu et al.   Chemical Science

Aggregates in monoclonal antibody manufacturing processes

(2011) María Vázquez-Rey et al.   BIOTECHNOLOGY AND BIOENGINEERING

Evaluation of selectivity in multimodal anion exchange systems: A priori prediction of protein retention and examination of mobile phase modifier effects

(2011) Ying Hou et al.   JOURNAL OF CHROMATOGRAPHY A

Antibody capture by mixed-mode chromatography: A comprehensive study from determination of optimal purification conditions to identification of contaminating host cell proteins

(2011) Jerome Pezzini et al.   JOURNAL OF CHROMATOGRAPHY A

Novel peptide ligand with high binding capacity for antibody purification

(2011) Line Naomi Lund et al.   JOURNAL OF CHROMATOGRAPHY A

Designing new monoclonal antibody purification processes using mixed-mode chromatography sorbents

(2011) Magali Toueille et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Molecular Simulations of Multimodal Ligand–Protein Binding: Elucidation of Binding Sites and Correlation with Experiments

(2011) Alexander S. Freed et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Glycosylation of the enhanced aromatic sequon is similarly stabilizing in three distinct reverse turn contexts

(2011) J. L. Price et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Phenomena and Modeling of Hydrophobic Interaction Chromatography

(2011) C. Borrmann et al.   SEPARATION SCIENCE AND TECHNOLOGY

Application of mixed mode resins for the purification of antibodies

(2010) Agnes Voitl et al.   JOURNAL OF CHROMATOGRAPHY A

High-throughput isotherm determination and thermodynamic modeling of protein adsorption on mixed mode adsorbents

(2010) Beckley K. Nfor et al.   JOURNAL OF CHROMATOGRAPHY A

“Clickable” affinity ligands for effective separation of glycoproteins

(2010) Thummaruk Suksrichavalit et al.   JOURNAL OF CHROMATOGRAPHY A

Application of a pH responsive multimodal hydrophobic interaction chromatography medium for the analysis of glycosylated proteins

(2010) K. Kallberg et al.   JOURNAL OF CHROMATOGRAPHY A

Capture of human monoclonal antibodies from a clarified cell culture supernatant by phenyl boronate chromatography

(2010) Ana M. Azevedo et al.   JOURNAL OF MOLECULAR RECOGNITION

Comparative Effects of pH and Ionic Strength on Protein–Protein Interactions, Unfolding, and Aggregation for IgG1 Antibodies

(2010) Erinc Sahin et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Mechanism of inactivation of influenza viruses by immobilized hydrophobic polycations

(2010) B. B. Hsu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Evaluation of protein adsorption and preferred binding regions in multimodal chromatography using NMR

(2010) W. K. Chung et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Glycomic Analysis: An Array of Technologies

(2009) Lakshmi Krishnamoorthy et al.   ACS Chemical Biology

Ligands for mixed-mode protein chromatography: Principles, characteristics and design

(2009) Guofeng Zhao et al.   JOURNAL OF BIOTECHNOLOGY

Synthesis and characterization of a new boronate affinity monolithic capillary for specific capture of cis-diol-containing compounds

(2009) Lianbing Ren et al.   JOURNAL OF CHROMATOGRAPHY A

A new thermodynamic model describes the effects of ligand density and type, salt concentration and protein species in hydrophobic interaction chromatography

(2009) R.W. Deitcher et al.   JOURNAL OF CHROMATOGRAPHY A

Glycoprotein Synthesis: An Update

(2008) David P. Gamblin et al.   CHEMICAL REVIEWS

Hydrophobic interaction chromatography of proteins

(2008) Brian C.S. To et al.   JOURNAL OF CHROMATOGRAPHY A

Probing protein surface accessibility of amino acid substitutions using hydrophobic interaction chromatography

(2008) Kristian Becker et al.   JOURNAL OF CHROMATOGRAPHY A

Multipurpose peptide tags for protein isolation

(2008) Kristian Becker et al.   JOURNAL OF CHROMATOGRAPHY A

Mixed-mode chromatography for fractionation of peptides, phosphopeptides, and sialylated glycopeptides

(2008) Martin Gilar et al.   JOURNAL OF CHROMATOGRAPHY A

Effect of phenyl sepharose ligand density on protein monomer/aggregate purification and separation using hydrophobic interaction chromatography

(2008) Justin T. McCue et al.   JOURNAL OF CHROMATOGRAPHY A

Characterization of multimodal hydrophobic interaction chromatography media useful for isolation of green fluorescent proteins with small structural differences

(2008) Kristian Becker et al.   JOURNAL OF MOLECULAR RECOGNITION

Development of a Single Column Method for the Separation of Lipid- and Protein-Derived Oligosaccharides

(2008) David C. A. Neville et al.   JOURNAL OF PROTEOME RESEARCH

Patch controlled protein adsorption in mixed-mode chromatography with benzylamine as functional ligand

(2007) Dong Gao et al.   BIOCHEMICAL ENGINEERING JOURNAL

Quality by design—Thermodynamic modelling of chromatographic separation of proteins

(2007) Jørgen M. Mollerup et al.   JOURNAL OF CHROMATOGRAPHY A

Comparison of standard and new generation hydrophobic interaction chromatography resins in the monoclonal antibody purification process

(2007) Jie Chen et al.   JOURNAL OF CHROMATOGRAPHY A