Using high throughput screening to define virus clearance by chromatography resins

High-throughput process development of chromatography steps: Advantages and limitations of different formats used

(2012) Karol M. Łącki   Biotechnology Journal

Applying high-throughput methods to develop a purification process for a highly glycosylated protein

(2012) Nooshafarin Sanaie et al.   Biotechnology Journal

Cation exchange chromatography provides effective retrovirus clearance for antibody purification processes

(2011) Lisa Connell-Crowley et al.   BIOTECHNOLOGY AND BIOENGINEERING

Antibody capture by mixed-mode chromatography: A comprehensive study from determination of optimal purification conditions to identification of contaminating host cell proteins

(2011) Jerome Pezzini et al.   JOURNAL OF CHROMATOGRAPHY A

High-throughput process development for biopharmaceutical drug substances

(2011) Rahul Bhambure et al.   TRENDS IN BIOTECHNOLOGY

Strategies for developing design spaces for viral clearance by anion exchange chromatography during monoclonal antibody production

(2010) Daniel M. Strauss et al.   BIOTECHNOLOGY PROGRESS

High-throughput isotherm determination and thermodynamic modeling of protein adsorption on mixed mode adsorbents

(2010) Beckley K. Nfor et al.   JOURNAL OF CHROMATOGRAPHY A

Understanding the mechanism of virus removal by Q sepharose fast flow chromatography during the purification of CHO-cell derived biotherapeutics

(2009) Daniel M. Strauss et al.   BIOTECHNOLOGY AND BIOENGINEERING

Removal of endogenous retrovirus-like particles from CHO-cell derived products using Q sepharose fast flow chromatography

(2009) Daniel M. Strauss et al.   BIOTECHNOLOGY PROGRESS

The distinctive separation attributes of mixed-mode resins and their application in monoclonal antibody downstream purification process

(2009) Jie Chen et al.   JOURNAL OF CHROMATOGRAPHY A

High-throughput screening of chromatographic separations: II. Hydrophobic interaction

(2008) Jack F. Kramarczyk et al.   BIOTECHNOLOGY AND BIOENGINEERING

High-throughput screening of chromatographic separations: IV. Ion-exchange

(2008) Brian D. Kelley et al.   BIOTECHNOLOGY AND BIOENGINEERING

High-throughput screening of chromatographic separations: III. Monoclonal antibodies on ceramic hydroxyapatite

(2008) David L. Wensel et al.   BIOTECHNOLOGY AND BIOENGINEERING

High-throughput screening of chromatographic separations: I. Method development and column modeling

(2008) Jonathan L. Coffman et al.   BIOTECHNOLOGY AND BIOENGINEERING

Weak partitioning chromatography for anion exchange purification of monoclonal antibodies

(2008) Brian D. Kelley et al.   BIOTECHNOLOGY AND BIOENGINEERING

A Novel, Q-PCR Based Approach to Measuring Endogenous Retroviral Clearance by Capture Protein A Chromatography

(2008) Min Zhang et al.   BIOTECHNOLOGY AND BIOENGINEERING

Anion exchange chromatography provides a robust, predictable process to ensure viral safety of biotechnology products

(2008) Daniel M. Strauss et al.   BIOTECHNOLOGY AND BIOENGINEERING

High-Throughput Process Development: Determination of Dynamic Binding Capacity Using Microtiter Filter Plates Filled with Chromatography Resin

(2008) T. Bergander et al.   BIOTECHNOLOGY PROGRESS

High Throughput Screening for the Design and Optimization of Chromatographic Processes – Miniaturization, Automation and Parallelization of Breakthrough and Elution Studies

(2008) M. Wiendahl et al.   CHEMICAL ENGINEERING & TECHNOLOGY

High Throughput Screening for the Design and Optimization of Chromatographic Processes: Assessment of Model Parameter Determination from High Throughput Compatible Data

(2008) A. Susanto et al.   CHEMICAL ENGINEERING & TECHNOLOGY

Robustness of virus removal by protein A chromatography is independent of media lifetime

(2008) Scott Lute et al.   JOURNAL OF CHROMATOGRAPHY A