Host cell protein analysis in therapeutic protein bioprocessing - methods and applications
Published 2013 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Host cell protein analysis in therapeutic protein bioprocessing - methods and applications
Authors
Keywords
-
Journal
Biotechnology Journal
Volume 8, Issue 6, Pages 655-670
Publisher
Wiley
Online
2013-02-22
DOI
10.1002/biot.201200018
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Studying host cell protein interactions with monoclonal antibodies using high throughput protein A chromatography
- (2012) Vikram N. Sisodiya et al. Biotechnology Journal
- Host cell protein adsorption characteristics during protein a chromatography
- (2012) Richard D. R. Tarrant et al. BIOTECHNOLOGY PROGRESS
- Optimization of protein sample preparation for two-dimensional electrophoresis
- (2012) Kristin N. Valente et al. ELECTROPHORESIS
- Full automation and validation of a flexible ELISA platform for host cell protein and protein A impurity detection in biopharmaceuticals
- (2012) Guillaume Rey et al. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
- A critical review on the use of modern sophisticated hyphenated tools in the characterization of impurities and degradation products
- (2012) Saranjit Singh et al. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
- Analysis of host-cell proteins in biotherapeutic proteins by comprehensive online two-dimensional liquid chromatography/mass spectrometry
- (2012) Catalin Doneanu et al. mAbs
- Host cell protein dynamics in the supernatant of a mAb producing CHO cell line
- (2011) A.S. Tait et al. BIOTECHNOLOGY AND BIOENGINEERING
- Rational engineering of Escherichia coli strains for plasmid biopharmaceutical manufacturing
- (2011) Geisa A. L. Gonçalves et al. Biotechnology Journal
- Mapping the yeast host cell response to recombinant membrane protein production: Relieving the biological bottlenecks
- (2011) Mark P. Ashe et al. Biotechnology Journal
- Mammalian cells as biopharmaceutical production hosts in the age of omics
- (2011) Stefanie Dietmair et al. Biotechnology Journal
- Select host cell proteins coelute with monoclonal antibodies in protein a chromatography
- (2011) Bartek Nogal et al. BIOTECHNOLOGY PROGRESS
- Capacitive immunosensor for the detection of host cell proteins
- (2011) Kosin Teeparuksapun et al. JOURNAL OF BIOTECHNOLOGY
- Antibody capture by mixed-mode chromatography: A comprehensive study from determination of optimal purification conditions to identification of contaminating host cell proteins
- (2011) Jerome Pezzini et al. JOURNAL OF CHROMATOGRAPHY A
- Identification of native Escherichia coli BL21 (DE3) proteins that bind to immobilized metal affinity chromatography under high imidazole conditions and use of 2D-DIGE to evaluate contamination pools with respect to recombinant protein expression level
- (2011) Patrick Bartlow et al. PROTEIN EXPRESSION AND PURIFICATION
- Fragmentation of a highly purified monoclonal antibody attributed to residual CHO cell protease activity
- (2010) Sharon X. Gao et al. BIOTECHNOLOGY AND BIOENGINEERING
- Post-translational modifications of protein biopharmaceuticals
- (2010) Gary Walsh DRUG DISCOVERY TODAY
- Two-dimensional difference fluorescence gel electrophoresis to verify the scale-up of a non-affinity-based downstream process for isolation of a therapeutic recombinant antibody
- (2010) Julita K. Grzeskowiak et al. ELECTROPHORESIS
- Forced degradation of fentanyl: Identification and analysis of impurities and degradants
- (2010) Anuradha Garg et al. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
- Identification of Pharmaceutical Impurities in Formulated Dosage Forms
- (2010) Changkang Pan et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Two-dimensional gel electrophoresis in proteomics: Past, present and future
- (2010) Thierry Rabilloud et al. Journal of Proteomics
- Expression, purification and characterization of the recombinant chimeric IgE Fc-fragment opossum–human–opossum (OSO), an active immunotherapeutic vaccine component
- (2010) Bingze Xu et al. PROTEIN EXPRESSION AND PURIFICATION
- Highlights on the capacities of "Gel-based" proteomics
- (2010) François Chevalier Proteome Science
- Recent advances in large-scale production of monoclonal antibodies and related proteins
- (2010) Abhinav A. Shukla et al. TRENDS IN BIOTECHNOLOGY
- Host cell proteins in biologics development: Identification, quantitation and risk assessment
- (2009) Xing Wang et al. BIOTECHNOLOGY AND BIOENGINEERING
- Profiling of host cell proteins by two-dimensional difference gel electrophoresis (2D-DIGE): Implications for downstream process development
- (2009) Mi Jin et al. BIOTECHNOLOGY AND BIOENGINEERING
- Product and contaminant measurement in bioprocess development by SELDI-MS
- (2009) Alex Berrill et al. BIOTECHNOLOGY PROGRESS
- Separation of product associatingE. colihost cell proteins OppA and DppA from recombinant apolipoprotein A-IMilanoin an industrial HIC unit operation
- (2009) Alan K. Hunter et al. BIOTECHNOLOGY PROGRESS
- Two-dimensional fluorescence difference gel electrophoresis for comparison of affinity and non-affinity based downstream processing of recombinant monoclonal antibody
- (2009) Julita K. Grzeskowiak et al. JOURNAL OF CHROMATOGRAPHY A
- LC and LC–MS/TOF studies on stress degradation behaviour of candesartan cilexetil
- (2009) Surbhi Mehta et al. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
- Characterization of degradation products of amorphous and polymorphic forms of clopidogrel bisulphate under solid state stress conditions
- (2009) Dhara K. Raijada et al. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
- 2-D DIGE to expedite downstream process development for human monoclonal antibody purification
- (2009) Julita K. Grzeskowiak et al. PROTEIN EXPRESSION AND PURIFICATION
- Immunochemical binding assays for detection and quantification of trace impurities in biotechnological production
- (2009) Bo Mattiasson et al. TRENDS IN BIOTECHNOLOGY
- Demonstration of Robust Host Cell Protein Clearance in Biopharmaceutical Downstream Processes
- (2008) A.A. Shukla et al. BIOTECHNOLOGY PROGRESS
- Host cell protein clearance during protein a chromatography: Development of an improved column wash step
- (2008) Abhinav A. Shukla et al. BIOTECHNOLOGY PROGRESS
- Proteomic Profiling of Secreted Proteins from CHO Cells Using Surface-Enhanced Laser Desorption Ionization Time-of-Flight Mass Spectrometry
- (2007) N. Kumar et al. BIOTECHNOLOGY PROGRESS
- Strategy for identification of leachables in packaged pharmaceutical liquid formulations
- (2007) Changkang Pan et al. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExplorePublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More