Imaging and tracing of intracellular metabolites utilizing genetically encoded fluorescent biosensors

Development of a Transferable Bimolecular Fluorescence Complementation System for the Investigation of Interactions between Poly(3-Hydroxybutyrate) Granule-Associated Proteins in Gram-Negative Bacteria

(2013) Daniel Pfeiffer et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Quantitative monitoring of 2-oxoglutarate in Escherichia coli cells by a fluorescence resonance energy transfer-based biosensor

(2013) Chang Zhang et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

A fluorescence resonance energy transfer (FRET)-based redox sensor reveals physiological role of thioredoxin in the yeastSaccharomyces cerevisiae

(2013) Masahide Oku et al.   FEBS LETTERS

A Genetically Encoded FRET Lactate Sensor and Its Use To Detect the Warburg Effect in Single Cancer Cells

(2013) Alejandro San Martín et al.   PLoS One

A Selective Fluorescent Probe for Carbon Monoxide Imaging in Living Cells

(2012) Jing Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Lighting up Carbon Monoxide: Fluorescent Probes for Monitoring CO in Living Cells

(2012) Lin Yuan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enhanced-acceptor fluorescence-based single cell ATP biosensor monitors ATP in heterogeneous cancer populations in real time

(2012) Sohila Zadran et al.   BIOTECHNOLOGY LETTERS

Visualization of Glutamine Transporter Activities in Living Cells Using Genetically Encoded Glutamine Sensors

(2012) Katrin Gruenwald et al.   PLoS One

New Alternately Colored FRET Sensors for Simultaneous Monitoring of Zn2+ in Multiple Cellular Locations

(2012) Jose G. Miranda et al.   PLoS One

Fluorescence Imaging of Cellular Metabolites with RNA

(2012) Jeremy S. Paige et al.   SCIENCE

Rapid Development of Genetically Encoded FRET Reporters

(2011) Alen Piljić et al.   ACS Chemical Biology

A Luminescent Biosensor with Increased Dynamic Range for Intracellular cAMP

(2011) Brock F. Binkowski et al.   ACS Chemical Biology

Enhanced dynamic range in a genetically encoded Ca2+ sensor

(2011) Shun Liu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The circularly permuted yellow fluorescent protein cpYFP that has been used as a superoxide probe is highly responsive to pH but not superoxide in mitochondria: implications for the existence of superoxide ‘flashes’

(2011) Markus Schwarzländer et al.   BIOCHEMICAL JOURNAL

Quantitative Measurement of Ca2+-Dependent Calmodulin–Target Binding by Fura-2 and CFP and YFP FRET Imaging in Living Cells

(2011) Masayuki X. Mori et al.   BIOCHEMISTRY

Imaging Cytosolic NADH-NAD+ Redox State with a Genetically Encoded Fluorescent Biosensor

(2011) Yin Pun Hung et al.   Cell Metabolism

Genetically Encoded Fluorescent Sensors for Intracellular NADH Detection

(2011) Yuzheng Zhao et al.   Cell Metabolism

Genetically Encodable Fluorescent Biosensors for Tracking Signaling Dynamics in Living Cells

(2011) Robert H. Newman et al.   CHEMICAL REVIEWS

Rational Design of Photoconvertible and Biphotochromic Fluorescent Proteins for Advanced Microscopy Applications

(2011) Virgile Adam et al.   CHEMISTRY & BIOLOGY

An Ion-insensitive cAMP Biosensor for Long Term Quantitative Ratiometric Fluorescence Resonance Energy Transfer (FRET) Measurements under Variable Physiological Conditions

(2011) Petrus S. Salonikidis et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Circular Permutation of Red Fluorescent Proteins

(2011) Bo Shui et al.   PLoS One

Engineering Genetically Encoded Nanosensors for Real-Time In Vivo Measurements of Citrate Concentrations

(2011) Jennifer C. Ewald et al.   PLoS One

Bioluminescence resonance energy transfer (BRET) imaging of protein-protein interactions within deep tissues of living subjects

(2011) A. Dragulescu-Andrasi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Extracellular ATP reduces tumor sphere growth and cancer stem cell population in glioblastoma cells

(2011) Pítia Flores Ledur et al.   Purinergic Signalling

RNA Mimics of Green Fluorescent Protein

(2011) J. S. Paige et al.   SCIENCE

A genetically encoded sensor for H2O2 with expanded dynamic range

(2010) Kseniya N. Markvicheva et al.   BIOORGANIC & MEDICINAL CHEMISTRY

A sensitive fluorescence reporter for monitoring quorum sensing regulated protease production in Vibrio harveyi

(2010) Sathish Rajamani et al.   JOURNAL OF MICROBIOLOGICAL METHODS

A Highly Selective Fluorescent Probe for Visualization of Organic Hydroperoxides in Living Cells

(2010) Boxuan Simen Zhao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Novel Fluorescent Sensor Protein for Visualization of Redox States in the Cytoplasm and in Peroxisomes

(2010) T. Yano et al.   MOLECULAR AND CELLULAR BIOLOGY

Glutamate receptors and signal transduction in learning and memory

(2010) Sheng Peng et al.   MOLECULAR BIOLOGY REPORTS

Circularly permuted monomeric red fluorescent proteins with new termini in the β-sheet

(2010) Haley J. Carlson et al.   PROTEIN SCIENCE

The Structure of Ca2+ Sensor Case16 Reveals the Mechanism of Reaction to Low Ca2+ Concentrations

(2010) Lukas Leder et al.   SENSORS

Constructing and Exploiting the Fluorescent Protein Paintbox (Nobel Lecture)

(2009) Roger Y. Tsien   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The fluorescent protein palette: tools for cellular imaging

(2009) Richard N. Day et al.   CHEMICAL SOCIETY REVIEWS

The role of membrane microdomains in shaping β2-adrenergic receptor-mediated cAMP dynamics

(2009) Lisa M. DiPilato et al.   Molecular BioSystems

A genetically encoded fluorescent reporter of ATP:ADP ratio

(2009) Jim Berg et al.   NATURE METHODS

Visualization of ATP levels inside single living cells with fluorescence resonance energy transfer-based genetically encoded indicators

(2009) H. Imamura et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Circular permutation of ligand-binding module improves dynamic range of genetically encoded FRET-based nanosensor

(2009) Satoshi Okada et al.   PROTEIN SCIENCE

Novel Genetically Encoded Biosensors Using Firefly Luciferase

(2008) Frank Fan et al.   ACS Chemical Biology

Role of NADH/NAD+ transport activity and glycogen store on skeletal muscle energy metabolism during exercise: in silico studies

(2008) Yanjun Li et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Fluorescence resonance energy transfer sensors for quantitative monitoring of pentose and disaccharide accumulation in bacteria

(2008) Thijs Kaper et al.   Biotechnology for Biofuels

Engineering Redox-Sensitive Linkers for Genetically Encoded FRET-Based Biosensors

(2008) Vladimir L. Kolossov et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Visualization of ternary complexes in living cells by using a BiFC-based FRET assay

(2008) Y John Shyu et al.   Nature Protocols

Increased Level of Extracellular ATP at Tumor Sites: In Vivo Imaging with Plasma Membrane Luciferase

(2008) Patrizia Pellegatti et al.   PLoS One

Optical measurement of synaptic glutamate spillover and reuptake by linker optimized glutamate-sensitive fluorescent reporters

(2008) S. A. Hires et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

High-Resolution Imaging of Redox Signaling in Live Cells Through an Oxidation-Sensitive Yellow Fluorescent Protein

(2008) G. Maulucci et al.   Science Signaling

Imaging of glutamate in brain slices using FRET sensors

(2007) Chris Dulla et al.   JOURNAL OF NEUROSCIENCE METHODS

Construction of a fluorescent biosensor family

(2002) Robert M. De Lorimier et al.   PROTEIN SCIENCE