Advances in the use of nanoscale bilayers to study membrane protein structure and function

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(2016)   Biotechnology Journal

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(2016)   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

A Conformational Investigation of Propeptide Binding to the Integral Membrane Protein γ-Glutamyl Carboxylase Using Nanodisc Hydrogen Exchange Mass Spectrometry

(2014) Christine H. Parker et al.   BIOCHEMISTRY

Quantifying Interactions of a Membrane Protein Embedded in a Lipid Nanodisc using Fluorescence Correlation Spectroscopy

(2014) Sonny Ly et al.   BIOPHYSICAL JOURNAL

Stealth carriers for low-resolution structure determination of membrane proteins in solution

(2014) Selma Maric et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Small-angle scattering gives direct structural information about a membrane protein inside a lipid environment

(2014) Søren A. R. Kynde et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Single Molecule Activity Measurements of Cytochrome P450 Oxidoreductase Reveal the Existence of Two Discrete Functional States

(2013) Tomas Laursen et al.   ACS Chemical Biology

Self-Assembled Porphyrin Nanodiscs with Structure-Dependent Activation for Phototherapy and Photodiagnostic Applications

(2013) Kenneth K. Ng et al.   ACS Nano

Interfacing Lipid Bilayer Nanodiscs and Silicon Photonic Sensor Arrays for Multiplexed Protein–Lipid and Protein–Membrane Protein Interaction Screening

(2013) Courtney D. Kuhnline Sloan et al.   ANALYTICAL CHEMISTRY

DEER EPR Measurements for Membrane Protein Structures via Bifunctional Spin Labels and Lipodisq Nanoparticles

(2013) Indra D. Sahu et al.   BIOCHEMISTRY

Assembly of an Activated Rhodopsin–Transducin Complex in Nanoscale Lipid Bilayers

(2013) Aaron M. D’Antona et al.   BIOCHEMISTRY

Radioligand Binding to Nanodisc-Reconstituted Membrane Transporters Assessed by the Scintillation Proximity Assay

(2013) Mahmoud L. Nasr et al.   BIOCHEMISTRY

Functional properties of cell-free expressed human endothelin A and endothelin B receptors in artificial membrane environments

(2013) Davide Proverbio et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

FhuA interactions in a detergent-free nanodisc environment

(2013) Allan Mills et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Conformational Dynamics of Calcium-Triggered Activation of Fusion by Synaptotagmin

(2013) Shyam S. Krishnakumar et al.   BIOPHYSICAL JOURNAL

A detergent-free strategy for the reconstitution of active enzyme complexes from native biological membranes into nanoscale discs

(2013) Ashley R Long et al.   BMC BIOTECHNOLOGY

Constitutively active rhodopsin mutants causing night blindness are effectively phosphorylated by GRKs but differ in arrestin-1 binding

(2013) Sergey. A. Vishnivetskiy et al.   CELLULAR SIGNALLING

Helical membrane protein conformations and their environment

(2013) Timothy A. Cross et al.   EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS

Elucidating the Native Architecture of the YidC: Ribosome Complex

(2013) Alexej Kedrov et al.   JOURNAL OF MOLECULAR BIOLOGY

Monitoring the Activity of Single Translocons

(2013) Intan Taufik et al.   JOURNAL OF MOLECULAR BIOLOGY

Membrane-Dependent Modulation of the mTOR Activator Rheb: NMR Observations of a GTPase Tethered to a Lipid-Bilayer Nanodisc

(2013) Mohammad T. Mazhab-Jafari et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Optimized Phospholipid Bilayer Nanodiscs Facilitate High-Resolution Structure Determination of Membrane Proteins

(2013) Franz Hagn et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Interpretation and Deconvolution of Nanodisc Native Mass Spectra

(2013) Michael T. Marty et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Nonlinear Analyte Concentration Gradients for One-Step Kinetic Analysis Employing Optical Microring Resonators

(2012) Michael T. Marty et al.   ANALYTICAL CHEMISTRY

Detergent-Free Formation and Physicochemical Characterization of Nanosized Lipid-Polymer Complexes: Lipodisq

(2012) Marcella C. Orwick et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Oxidase uncoupling in heme monooxygenases: Human cytochrome P450 CYP3A4 in Nanodiscs

(2012) Yelena V. Grinkova et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The stability and activity of respiratory Complex II is cardiolipin-dependent

(2012) Christine T. Schwall et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Characterization of co-translationally formed nanodisc complexes with small multidrug transporters, proteorhodopsin and with the E. coli MraY translocase

(2012) Christian Roos et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Lipid–protein nanodiscs promote in vitro folding of transmembrane domains of multi-helical and multimeric membrane proteins

(2012) Zakhar O. Shenkarev et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Monitoring Shifts in the Conformation Equilibrium of the Membrane Protein Cytochrome P450 Reductase (POR) in Nanodiscs

(2012) Maria Wadsäter et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

NMR Analyses of the Interaction between the FYVE Domain of Early Endosome Antigen 1 (EEA1) and Phosphoinositide Embedded in a Lipid Bilayer

(2012) Mariko Yokogawa et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Detergent-Free Incorporation of a Seven-Transmembrane Receptor Protein into Nanosized Bilayer Lipodisq Particles for Functional and Biophysical Studies

(2012) Marcella Orwick-Rydmark et al.   NANO LETTERS

The Cell-Free Integration of a Polytopic Mitochondrial Membrane Protein into Liposomes Occurs Cotranslationally and in a Lipid-Dependent Manner

(2012) Ashley R. Long et al.   PLoS One

Biomimetic Chemical Sensors Using Nanoelectronic Readout of Olfactory Receptor Proteins

(2011) Brett R. Goldsmith et al.   ACS Nano

Single-Molecule Force Spectroscopy from Nanodiscs: An Assay to Quantify Folding, Stability, and Interactions of Native Membrane Proteins

(2011) Michael Zocher et al.   ACS Nano

Nanodiscs versus Macrodiscs for NMR of Membrane Proteins

(2011) Sang Ho Park et al.   BIOCHEMISTRY

Lipid–protein nanodiscs for cell-free production of integral membrane proteins in a soluble and folded state: Comparison with detergent micelles, bicelles and liposomes

(2011) E.N. Lyukmanova et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Solution NMR spectroscopic characterization of human VDAC-2 in detergent micelles and lipid bilayer nanodiscs

(2011) Tsyr-Yan Yu et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Cell-free synthesis of a functional G protein-coupled receptor complexed with nanometer scale bilayer discs

(2011) Jian-Ping Yang et al.   BMC BIOTECHNOLOGY

Catalytic activity of MsbA reconstituted in nanodisc particles is modulated by remote interactions with the bilayer

(2011) Takeaki Kawai et al.   FEBS LETTERS

Reconstitution of respiratory oxidases in membrane nanodiscs for investigation of proton-coupled electron transfer

(2011) Linda Näsvik Öjemyr et al.   FEBS LETTERS

Nanodiscs and SILAC-Based Mass Spectrometry to Identify a Membrane Protein Interactome

(2011) Xiao X. Zhang et al.   JOURNAL OF PROTEOME RESEARCH

Green Proteorhodopsin Reconstituted into Nanoscale Phospholipid Bilayers (Nanodiscs) as Photoactive Monomers

(2011) Matthew J. Ranaghan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Nanodisc-based Co-immunoprecipitation for Mass Spectrometric Identification of Membrane-interacting Proteins

(2011) Jonas Borch et al.   MOLECULAR & CELLULAR PROTEOMICS

Monomeric Rhodopsin Is Sufficient for Normal Rhodopsin Kinase (GRK1) Phosphorylation and Arrestin-1 Binding

(2010) Timothy H. Bayburt et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lipid−Protein Nanodiscs as Reference Medium in Detergent Screening for High-Resolution NMR Studies of Integral Membrane Proteins

(2010) Zakhar O. Shenkarev et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Photoelectrochemical complexes for solar energy conversion that chemically and autonomously regenerate

(2010) Moon-Ho Ham et al.   Nature Chemistry

Advances in cell-free protein synthesis for the functional and structural analysis of membrane proteins

(2010) Friederike Junge et al.   New Biotechnology

Genome-wide analysis of integral membrane proteins from eubacterial, archaean, and eukaryotic organisms

(2010) Erik Wallin et al.   PROTEIN SCIENCE

Modulation of the Cytochrome P450 Reductase Redox Potential by the Phospholipid Bilayer

(2009) Aditi Das et al.   BIOCHEMISTRY

Integral Membrane Proteins in Nanodiscs Can Be Studied by Solution NMR Spectroscopy

(2009) Julian M. Glück et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Structural and Functional Characterization of the Integral Membrane Protein VDAC-1 in Lipid Bilayer Nanodiscs

(2009) Thomas Raschle et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Static and Dynamic Properties of Phospholipid Bilayer Nanodiscs

(2009) Minoru Nakano et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Membrane Proteins Solubilized Intact in Lipid Containing Nanoparticles Bounded by Styrene Maleic Acid Copolymer

(2009) Timothy J. Knowles et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Insertion of Membrane Proteins into Discoidal Membranes Using a Cell-Free Protein Expression Approach

(2008) Federico Katzen et al.   JOURNAL OF PROTEOME RESEARCH

Cell-free Co-expression of Functional Membrane Proteins and Apolipoprotein, Forming Soluble Nanolipoprotein Particles

(2008) Jenny A. Cappuccio et al.   MOLECULAR & CELLULAR PROTEOMICS

A Method to Determine Dielectric Constants in Nonhomogeneous Systems: Application to Biological Membranes

(2007) Hugh Nymeyer et al.   BIOPHYSICAL JOURNAL

Self-assembly of single integral membrane proteins into soluble nanoscale phospholipid bilayers

(2003) Timothy H. Bayburt et al.   PROTEIN SCIENCE