Simvastatin Restored Vascular Reactivity, Endothelial Function and Reduced String Vessel Pathology in a Mouse Model of Cerebrovascular Disease

Neuroinflammation in the pathogenesis of Alzheimer’s disease. A rational framework for the search of novel therapeutic approaches

(2014) Inelia Morales et al.   Frontiers in Cellular Neuroscience

Endothelial TRPV4 channels mediate dilation of cerebral arteries: impairment and recovery in cerebrovascular pathologies related to Alzheimer's disease

(2013) Luqing Zhang et al.   BRITISH JOURNAL OF PHARMACOLOGY

Vascular Calcification: An Update on Mechanisms and Challenges in Treatment

(2013) Meiting Wu et al.   CALCIFIED TISSUE INTERNATIONAL

Effect of simvastatin on the antihypertensive activity of losartan in hypertensive hypercholesterolemic animals and patients: Role of nitric oxide, oxidative stress, and high-sensitivity C-reactive protein

(2013) Ahmed O. Abdel-Zaher et al.   FUNDAMENTAL & CLINICAL PHARMACOLOGY

Chronic over-expression of TGFβ1 alters hippocampal structure and causes learning deficits

(2013) Alonso Martinez-Canabal et al.   HIPPOCAMPUS

Vascular Aspects of Cognitive Impairment and Dementia

(2013) Maximilian Wiesmann et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

The Pathobiology of Vascular Dementia

(2013) Costantino Iadecola   NEURON

Simvastatin inhibits transforming growth factor-β1-induced expression of type I collagen, CTGF, and α-SMA in keloid fibroblasts

(2013) Je-Ho Mun et al.   WOUND REPAIR AND REGENERATION

Simvastatin increases circulating endothelial progenitor cells and reduces the formation and progression of diabetic retinopathy in rats

(2012) Wei Zhang et al.   EXPERIMENTAL EYE RESEARCH

Chronic Cerebral Hypoxia Promotes Arteriogenic Remodeling Events that can be Identified by Reduced Endoglin (CD105) Expression and a Switch in β1 Integrins

(2012) Amin Boroujerdi et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Age-Dependent Rescue by Simvastatin of Alzheimer's Disease Cerebrovascular and Memory Deficits

(2012) X.-K. Tong et al.   JOURNAL OF NEUROSCIENCE

Bisphosphonate- and statin-induced enhancement of OPG expression and inhibition of CD9, M-CSF, and RANKL expressions via inhibition of the Ras/MEK/ERK pathway and activation of p38MAPK in mouse bone marrow stromal cell line ST2

(2012) Masanobu Tsubaki et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

TGF- 1 Induces Endothelial Cell Apoptosis by Shifting VEGF Activation of p38MAPK from the Prosurvival p38  to Proapoptotic p38 

(2012) G. Ferrari et al.   MOLECULAR CANCER RESEARCH

Morphological and Pathological Evolution of the Brain Microcirculation in Aging and Alzheimer’s Disease

(2012) Jesse M. Hunter et al.   PLoS One

The CC genotype of transforming growth factor-β1 increases the risk of late-onset Alzheimer's disease and is associated with AD-related depression

(2011) Filippo Caraci et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Cerebral Autosomal Recessive Arteriopathy with Subcortical Infarcts and Leukoencephalopathy (CARASIL): From Discovery to Gene Identification

(2011) Toshio Fukutake   Journal of Stroke & Cerebrovascular Diseases

Immunotherapy of cerebrovascular amyloidosis in a transgenic mouse model

(2011) Veronica Lifshitz et al.   NEUROBIOLOGY OF AGING

A randomized, double-blind, placebo-controlled trial of simvastatin to treat Alzheimer disease

(2011) M. Sano et al.   NEUROLOGY

Mechanism of the inhibitory effect of atorvastatin on endoglin expression induced by transforming growth factor-β1 in cultured cardiac fibroblasts

(2010) Kou-Gi Shyu et al.   EUROPEAN JOURNAL OF HEART FAILURE

Intact Memory in TGF-β1 Transgenic Mice Featuring Chronic Cerebrovascular Deficit: Recovery with Pioglitazone

(2010) Nektaria Nicolakakis et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Review: Cerebral microvascular pathology in ageing and neurodegeneration

(2010) W. R. Brown et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Regulation of the endothelial plasminogen activator system by fluvastatin

(2010) Sylvie Dunoyer-Geindre et al.   THROMBOSIS AND HAEMOSTASIS

RANKL Increases Vascular Smooth Muscle Cell Calcification Through a RANK-BMP4–Dependent Pathway

(2009) Sara Panizo et al.   CIRCULATION RESEARCH