Neuroinflammation in the pathogenesis of Alzheimer’s disease. A rational framework for the search of novel therapeutic approaches

Fulvic Acid Inhibits Aggregation and Promotes Disassembly of Tau Fibrils Associated with Alzheimer's Disease

(2018) Alberto Cornejo et al.   JOURNAL OF ALZHEIMERS DISEASE

Human Platelets Tau: A Potential Peripheral Marker for Alzheimer's Disease

(2018) Karen Neumann et al.   JOURNAL OF ALZHEIMERS DISEASE

Tau Oligomers and Fibrils Induce Activation of Microglial Cells

(2018) Inelia Morales et al.   JOURNAL OF ALZHEIMERS DISEASE

Neuropathology and the Neuroinflammation Idea

(2017) Robert E. Mrak   JOURNAL OF ALZHEIMERS DISEASE

Effects of Gingko biloba supplementation in Alzheimer's disease patients receiving cholinesterase inhibitors: Data from the ICTUS study

(2014) Marco Canevelli et al.   PHYTOMEDICINE

Amyloid beta deregulates astroglial mGluR5-mediated calcium signaling via calcineurin and Nf-kB

(2013) Dmitry Lim et al.   GLIA

A critical role of astrocyte-mediated nuclear factor-κB-dependent inflammation in Huntington's disease

(2013) Han-Yun Hsiao et al.   HUMAN MOLECULAR GENETICS

MHCII Is Required for  -Synuclein-Induced Activation of Microglia, CD4 T Cell Proliferation, and Dopaminergic Neurodegeneration

(2013) A. S. Harms et al.   JOURNAL OF NEUROSCIENCE

Innate Immunity and Neuroinflammation

(2013) Abhishek Shastri et al.   MEDIATORS OF INFLAMMATION

Curcumin promotes neurite outgrowth via reggie-1/flotillin-2 in cortical neurons

(2013) Zhengyu Lu et al.   NEUROSCIENCE LETTERS

Exposure to Inflammatory Cytokines IL-1β and TNFα Induces Compromise and Death of Astrocytes; Implications for Chronic Neuroinflammation

(2013) Christa van Kralingen et al.   PLoS One

Curcumin protects organotypic hippocampal slice cultures from Aβ1–42-induced synaptic toxicity

(2013) Juliana Bender Hoppe et al.   TOXICOLOGY IN VITRO

Astrocyte Form and Function in the Developing Central Nervous System

(2013) Lesley S. Chaboub et al.   Seminars in Pediatric Neurology

Origin and differentiation of microglia

(2013) Florent Ginhoux et al.   Frontiers in Cellular Neuroscience

Can Nutraceuticals Prevent Alzheimer's Disease? Potential Therapeutic Role of a Formulation Containing Shilajit and Complex B Vitamins

(2012) Carlos Carrasco-Gallardo et al.   ARCHIVES OF MEDICAL RESEARCH

Design, synthesis, and evaluation of resveratrol derivatives as Aß1–42 aggregation inhibitors, antioxidants, and neuroprotective agents

(2012) Chuanjun Lu et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Editorial [Hot topic: Inflammation, Immunity, and Alzheimers Disease (Guest Editor: Terrence Town)]

(2012) Terrence Town   CNS & Neurological Disorders-Drug Targets

Assessing Activation States in Microglia

(2012) Carol A. Colton et al.   CNS & Neurological Disorders-Drug Targets

Cyclooxygenase-1 inhibition reduces amyloid pathology and improves memory deficits in a mouse model of Alzheimer's disease

(2012) Sang-Ho Choi et al.   JOURNAL OF NEUROCHEMISTRY

Neuroprotective function for ramified microglia in hippocampal excitotoxicity

(2012) Jonathan Vinet et al.   Journal of Neuroinflammation

Long-term use of standardised ginkgo biloba extract for the prevention of Alzheimer's disease (GuidAge): a randomised placebo-controlled trial

(2012) Bruno Vellas et al.   LANCET NEUROLOGY

Thrombospondins as key regulators of synaptogenesis in the central nervous system

(2012) W. Christopher Risher et al.   MATRIX BIOLOGY

Acacetin Attenuates Neuroinflammation via Regulation the Response to LPS Stimuli In Vitro and In Vivo

(2012) Sang Keun Ha et al.   NEUROCHEMICAL RESEARCH

Alterations of Gene Expression and Glutamate Clearance in Astrocytes Derived from an MeCP2-Null Mouse Model of Rett Syndrome

(2012) Yasunori Okabe et al.   PLoS One

Editorial[Hot Topic: Tau Protein and Alzheimers Disease. New Paradigms and Future Challenges (Guest Editor: Ricardo B. Maccioni)]

(2011) Ricardo B. Maccioni   Current Alzheimer Research

Effects of non-steroidal anti-inflammatory drug treatments on cognitive decline vary by phase of pre-clinical Alzheimer disease: findings from the randomized controlled Alzheimer's Disease Anti-inflammatory Prevention Trial

(2011) Jeannie-Marie S. Leoutsakos et al.   INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY

Microglia Shape Adult Hippocampal Neurogenesis through Apoptosis-Coupled Phagocytosis

(2010) Amanda Sierra et al.   Cell Stem Cell

Alzheimer's disease: strategies for disease modification

(2010) Martin Citron   NATURE REVIEWS DRUG DISCOVERY

Microglia in neurodegenerative disease

(2010) V. Hugh Perry et al.   Nature Reviews Neurology

Neuroimmunomodulation in the Pathogenesis of Alzheimer’s Disease

(2010) Inelia Morales et al.   NEUROIMMUNOMODULATION

Astrocytes in Alzheimer’s disease

(2010) Alexei Verkhratsky et al.   Neurotherapeutics

Role of glutamate in neuron-glia metabolic coupling

(2009) Pierre J Magistretti   AMERICAN JOURNAL OF CLINICAL NUTRITION

Heterogeneity in astrocyte morphology and physiology

(2009) Vitali Matyash et al.   BRAIN RESEARCH REVIEWS

Population Variation in Glial Fibrillary Acidic Protein Levels in Brain Ageing: Relationship to Alzheimer-Type Pathology and Dementia

(2009) S.B. Wharton et al.   DEMENTIA AND GERIATRIC COGNITIVE DISORDERS

NSAIDs prevent, but do not reverse, neuronal cell cycle reentry in a mouse model of Alzheimer disease

(2009) Nicholas H. Varvel et al.   JOURNAL OF CLINICAL INVESTIGATION

Does neuroinflammation fan the flame in neurodegenerative diseases?

(2009) Tamy C Frank-Cannon et al.   Molecular Neurodegeneration

Synthesis and biological evaluation of a library of resveratrol analogues as inhibitors of COX-1, COX-2 and NF-κB

(2008) Soo Sung Kang et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Potential therapeutic effects of curcumin, the anti-inflammatory agent, against neurodegenerative, cardiovascular, pulmonary, metabolic, autoimmune and neoplastic diseases

(2008) Bharat B. Aggarwal et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Curcumin Stimulates Proliferation of Embryonic Neural Progenitor Cells and Neurogenesis in the Adult Hippocampus

(2008) So Jung Kim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Imaging Microglial Activation During Neuroinflammation and Alzheimer’s Disease

(2008) Sriram Venneti et al.   Journal of Neuroimmune Pharmacology

Gene, Cell, and Axon Changes in the Familial Amyotrophic Lateral Sclerosis Mouse Sensorimotor Cortex

(2008) Roman M. Kassa et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Astrocyte phenotype in relation to Alzheimer-type pathology in the ageing brain

(2008) J.E. Simpson et al.   NEUROBIOLOGY OF AGING

Protective effects of NSAIDs on the development of Alzheimer disease

(2008) Steven C. Vlad et al.   NEUROLOGY

The Mystery and Magic of Glia: A Perspective on Their Roles in Health and Disease

(2008) Ben A. Barres   NEURON