Simvastatin inhibits transforming growth factor-β1-induced expression of type I collagen, CTGF, and α-SMA in keloid fibroblasts

Development, validation and testing of a human tissue engineered hypertrophic scar model

(2014) Leonarda van den Broek   ALTEX-Alternatives to Animal Experimentation

Simvastatin attenuates the development of pulmonary and cutaneous fibrosis in a murine model of systemic sclerosis

(2013) G. Bagnato et al.   RHEUMATOLOGY

Effect of Simvastatin on Transforming Growth Factor Beta-1–Induced Myofibroblast Differentiation and Collagen Production in Nasal Polyp-Derived Fibroblasts

(2012) Il-Ho Park et al.   American Journal of Rhinology & Allergy

HMG-CoA Reductase Inhibitors (Statins) Reduce Hypertrophic Scar Formation in a Rabbit Ear Wounding Model

(2012) Jason H. Ko et al.   PLASTIC AND RECONSTRUCTIVE SURGERY

Simvastatin Attenuates Intestinal Fibrosis Independent of the Anti-Inflammatory Effect by Promoting Fibroblast/Myofibroblast Apoptosis in the Regeneration/Healing Process from TNBS-Induced Colitis

(2011) Yosuke Abe et al.   DIGESTIVE DISEASES AND SCIENCES

Protective effects of statin on cardiac fibrosis and apoptosis in adrenomedullin-knockout mice treated with angiotensin II and high salt loading

(2010) Chii Yamamoto et al.   HYPERTENSION RESEARCH

Simvastatin impairs smad-3 phosphorylation and modulates transforming growth factor β1-mediated activation of intestinal fibroblasts

(2009) J. P. Burke et al.   BRITISH JOURNAL OF SURGERY

Simvastatin attenuates experimental small airway remodelling in rats

(2009) Xue-Mei OU et al.   RESPIROLOGY

Transforming Growth Factor-β1 (TGFβ1) Stimulates Connective Tissue Growth Factor (CCN2/CTGF) Expression in Human Gingival Fibroblasts through a RhoA-independent, Rac1/Cdc42-dependent Mechanism

(2008) Samuel A. Black et al.   JOURNAL OF BIOLOGICAL CHEMISTRY