The Many Faces of the A2b Adenosine Receptor in Cardiovascular and Metabolic Diseases

The Role of Adenosine Signaling in Sickle Cell Therapeutics

(2014) Joshua J. Field et al.   HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA

An Adenosine Receptor-Krüppel-like Factor 4 Protein Axis Inhibits Adipogenesis

(2014) Anna Eisenstein et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Macrophage A2b Adenosine Receptor Regulates Tissue Insulin Sensitivity

(2014) Hillary Johnston-Cox et al.   PLoS One

Elevated Ecto-5'-nucleotidase-Mediated Increased Renal Adenosine Signaling Via A2B Adenosine Receptor Contributes to Chronic Hypertension

(2013) Weiru Zhang et al.   CIRCULATION RESEARCH

A2B Adenosine Receptors Prevent Insulin Resistance by Inhibiting Adipose Tissue Inflammation via Maintaining Alternative Macrophage Activation

(2013) B. Csoka et al.   DIABETES

Adora2b Signaling on Bone Marrow Derived Cells Dampens Myocardial Ischemia-Reperfusion Injury

(2012) Michael Koeppen et al.   ANESTHESIOLOGY

Adenosine A 2B Receptor Agonism Inhibits Neointimal Lesion Development After Arterial Injury in Apolipoprotein E–Deficient Mice

(2012) Ilze Bot et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

The A2B adenosine receptor modulates pulmonary hypertension associated with interstitial lung disease

(2012) Harry Karmouty-Quintana et al.   FASEB JOURNAL

A novel mechanism of control of NF B activation and inflammation involving A2B adenosine receptors

(2012) Y. Sun et al.   JOURNAL OF CELL SCIENCE

Adora2b-elicited Per2 stabilization promotes a HIF-dependent metabolic switch crucial for myocardial adaptation to ischemia

(2012) Tobias Eckle et al.   NATURE MEDICINE

The A2b Adenosine Receptor Modulates Glucose Homeostasis and Obesity

(2012) Hillary Johnston-Cox et al.   PLoS One

2′,3′-cAMP, 3′-AMP, and 2′-AMP inhibit human aortic and coronary vascular smooth muscle cell proliferation via A2B receptors

(2011) Edwin K. Jackson et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Macrophages in the Pathogenesis of Atherosclerosis

(2011) Kathryn J. Moore et al.   CELL

A 2b Adenosine Receptor Regulates Hyperlipidemia and Atherosclerosis

(2011) Milka Koupenova et al.   CIRCULATION

Links Between Insulin Resistance, Adenosine A2B Receptors, and Inflammatory Markers in Mice and Humans

(2011) R. A. Figler et al.   DIABETES

Adenosine promotes alternative macrophage activation via A2A and A2B receptors

(2011) Balázs Csóka et al.   FASEB JOURNAL

A Role for the Low-Affinity A2B Adenosine Receptor in Regulating Superoxide Generation by Murine Neutrophils

(2011) D. van der Hoeven et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

A Randomized, Double-Blind, Multicenter Comparison Study of Triple Antiplatelet Therapy With Dual Antiplatelet Therapy to Reduce Restenosis After Drug-Eluting Stent Implantation in Long Coronary Lesions

(2011) Seung-Whan Lee et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Progress and challenges in translating the biology of atherosclerosis

(2011) Peter Libby et al.   NATURE

The immune system in atherosclerosis

(2011) Göran K Hansson et al.   NATURE IMMUNOLOGY

Atherosclerosis: current pathogenesis and therapeutic options

(2011) Christian Weber et al.   NATURE MEDICINE

Hypoxia and Inflammation

(2011) Holger K. Eltzschig et al.   NEW ENGLAND JOURNAL OF MEDICINE

International Union of Basic and Clinical Pharmacology. LXXXI. Nomenclature and Classification of Adenosine Receptors--An Update

(2011) B. B. Fredholm et al.   PHARMACOLOGICAL REVIEWS

Interleukin-6 Contributes to Inflammation and Remodeling in a Model of Adenosine Mediated Lung Injury

(2011) Mesias Pedroza et al.   PLoS One

Development of Polar Adenosine A2A Receptor Agonists for Inflammatory Bowel Disease: Synergism with A2B Antagonists

(2011) Ali El-Tayeb et al.   ACS Medicinal Chemistry Letters

A2B Adenosine Receptors Protect against Sepsis-Induced Mortality by Dampening Excessive Inflammation

(2010) B. Csoka et al.   JOURNAL OF IMMUNOLOGY

Evidence that the acute phase of ischemic preconditioning does not require signaling by the A2B adenosine receptor

(2010) Jason E. Maas et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

In-Stent Restenosis in the Drug-Eluting Stent Era

(2010) George D. Dangas et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Tissue-derived proinflammatory effect of adenosine A2B receptor in lung ischemia–reperfusion injury

(2010) Farshad Anvari et al.   JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY

Monocytes in atherosclerosis: subsets and functions

(2010) Kevin J. Woollard et al.   Nature Reviews Cardiology

Attenuation of Chronic Pulmonary Inflammation in A2BAdenosine Receptor Knockout Mice

(2009) Rinat Zaynagetdinov et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Adenosine Modulates HIF-1α, VEGF, IL-8, and Foam Cell Formation in a Human Model of Hypoxic Foam Cells

(2009) Stefania Gessi et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Chemokines in the vascular inflammatory response of atherosclerosis

(2009) A. Zernecke et al.   CARDIOVASCULAR RESEARCH

Enhanced Airway Inflammation and Remodeling in Adenosine Deaminase-Deficient Mice Lacking the A2B Adenosine Receptor

(2009) Y. Zhou et al.   JOURNAL OF IMMUNOLOGY

Adenosine A2A and A2B receptors work in concert to induce a strong protection against reperfusion injury in rat hearts

(2009) Jinkun Xi et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

C-reactive protein concentration and risk of coronary heart disease, stroke, and mortality: an individual participant meta-analysis

(2009)   LANCET

TNF-α upregulates the A 2B adenosine receptor gene: The role of NAD(P)H oxidase 4

(2008) Cynthia St. Hilaire et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Blockade of adenosine A2Breceptors ameliorates murine colitis

(2008) V L Kolachala et al.   BRITISH JOURNAL OF PHARMACOLOGY

Hypoxia-Inducible Factor-1 Is Central to Cardioprotection

(2008) Tobias Eckle et al.   CIRCULATION

Discovery of a Novel A2BAdenosine Receptor Antagonist as a Clinical Candidate for Chronic Inflammatory Airway Diseases

(2008) Elfatih Elzein et al.   JOURNAL OF MEDICINAL CHEMISTRY

Hypoxia, Hypoxia-Inducible Transcription Factor, and Macrophages in Human Atherosclerotic Plaques Are Correlated With Intraplaque Angiogenesis

(2008) Judith C. Sluimer et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Vascular smooth muscle cell signaling mechanisms for contraction to angiotensin II and endothelin-1

(2008) Brandi M. Wynne et al.   Journal of the American Society of Hypertension

Adenosine receptors: therapeutic aspects for inflammatory and immune diseases

(2008) György Haskó et al.   NATURE REVIEWS DRUG DISCOVERY

The A2b adenosine receptor protects against vascular injury

(2008) D. Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA