Increasing 3D Matrix Rigidity Strengthens Proliferation and Spheroid Development of Human Liver Cells in a Constant Growth Factor Environment

3D Organotypic Cultures of Human HepaRG Cells: A Tool for In Vitro Toxicity Studies

(2013) Patrina Gunness et al.   TOXICOLOGICAL SCIENCES

A long-term three dimensional liver co-culture system for improved prediction of clinically relevant drug-induced hepatotoxicity

(2013) Radina Kostadinova et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Influence of a three-dimensional, microarray environment on human Cell culture in drug screening systems

(2012) Luciana Meli et al.   BIOMATERIALS

MAPK signaling in cisplatin-induced death: predominant role of ERK1 over ERK2 in human hepatocellular carcinoma cells

(2012) Jean-Philippe Guégan et al.   CARCINOGENESIS

Second harmonic generation microscopy for quantitative analysis of collagen fibrillar structure

(2012) Xiyi Chen et al.   Nature Protocols

Three-Dimensional HepaRG Model As An Attractive Tool for Toxicity Testing

(2012) Sofia B. Leite et al.   TOXICOLOGICAL SCIENCES

Mechanisms of hepatic fibrogenesis

(2011) Ursula E. Lee et al.   BEST PRACTICE & RESEARCH IN CLINICAL GASTROENTEROLOGY

Liver Fibrosis Protects Mice From Acute Hepatocellular Injury

(2011) Éric Bourbonnais et al.   GASTROENTEROLOGY

The complexity of ERK1 and ERK2 MAPKs in multiple hepatocyte fate responses

(2011) Christophe Frémin et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Cell Motility and Mechanics in Three-Dimensional Collagen Matrices

(2010) Frederick Grinnell et al.   Annual Review of Cell and Developmental Biology

Matrix stiffness modulates proliferation, chemotherapeutic response, and dormancy in hepatocellular carcinoma cells

(2010) Jörg Schrader et al.   HEPATOLOGY

Induction of liver fibrosis in a murine hepatoma model by thioacetamide is associated with enhanced tumor growth and suppressed antitumor immunity

(2010) Ming-Chen Yang et al.   LABORATORY INVESTIGATION

Accelerated orthotopic hepatocellular carcinomas growth is linked to increased expression of pro-angiogenic and prometastatic factors in murine liver fibrosis

(2010) Miroslaw Kornek et al.   LIVER INTERNATIONAL

Signalling ballet in space and time

(2010) Boris N. Kholodenko et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Prospective risk assessment for hepatocellular carcinoma development in patients with chronic hepatitis C by transient elastography

(2009) Ryota Masuzaki et al.   HEPATOLOGY

Multiple division cycles and long-term survival of hepatocytes are distinctly regulated by extracellular signal-regulated kinases ERK1 and ERK2

(2009) Christophe Frémin et al.   HEPATOLOGY

Extracellular matrix modulates sensitivity of hepatocytes to fibroblastoid dedifferentiation and transforming growth factor β-induced apoptosis

(2009) Patricio Godoy et al.   HEPATOLOGY

Liver fibrosis

(2008) Karen Wallace et al.   BIOCHEMICAL JOURNAL

Collagen density promotes mammary tumor initiation and progression

(2008) Paolo P Provenzano et al.   BMC Medicine

RNAi-mediated ERK2 knockdown inhibits growth of tumor cells in vitro and in vivo

(2008) A Bessard et al.   ONCOGENE