Akt signaling dynamics in individual cells

Single-cell Analysis of G-protein Signal Transduction

(2015) Terri Clister et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dynamic Visualization of mTORC1 Activity in Living Cells

(2015) Xin Zhou et al.   Cell Reports

Signal Transduction in Cancer

(2015) R. Sever et al.   Cold Spring Harbor Perspectives in Medicine

High-Sensitivity Measurements of Multiple Kinase Activities in Live Single Cells

(2014) Sergi Regot et al.   CELL

The unique activity of bone morphogenetic proteins in bone: a critical role of the Smad signaling pathway

(2013) Takenobu Katagiri et al.   BIOLOGICAL CHEMISTRY

Using Optogenetics to Interrogate the Dynamic Control of Signal Transmission by the Ras/Erk Module

(2013) Jared E. Toettcher et al.   CELL

Encoding and Decoding Cellular Information through Signaling Dynamics

(2013) Jeremy E. Purvis et al.   CELL

The Proliferation-Quiescence Decision Is Controlled by a Bifurcation in CDK2 Activity at Mitotic Exit

(2013) Sabrina L. Spencer et al.   CELL

Development of a FRET Biosensor with High Specificity for Akt

(2013) Haruko Miura et al.   CELL STRUCTURE AND FUNCTION

Proteome-Wide Measurement of Protein Half-Lives and Translation Rates in Vasopressin-Sensitive Collecting Duct Cells

(2013) P. C. Sandoval et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Tunable Signal Processing Through Modular Control of Transcription Factor Translocation

(2013) N. Hao et al.   SCIENCE

The RAS/RAF/MEK/ERK and the PI3K/AKT signalling pathways: role in cancer pathogenesis and implications for therapeutic approaches

(2012) Antonella De Luca et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

The decline and fall of the IGF-I receptor

(2012) Renato Baserga   JOURNAL OF CELLULAR PHYSIOLOGY

Insulin-like Growth Factor Receptor Inhibitors: Baby or the Bathwater?

(2012) D. Yee   JNCI-Journal of the National Cancer Institute

Dynamic Response Diversity of NFAT Isoforms in Individual Living Cells

(2012) Nissan Yissachar et al.   MOLECULAR CELL

Frequency-Modulated Pulses of ERK Activity Transmit Quantitative Proliferation Signals

(2012) John G. Albeck et al.   MOLECULAR CELL

Improving FRET dynamic range with bright green and red fluorescent proteins

(2012) Amy J Lam et al.   NATURE METHODS

p53 Dynamics Control Cell Fate

(2012) J. E. Purvis et al.   SCIENCE

Interplay between FOXO, TOR, and Akt

(2011) Nissim Hay   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Development of an optimized backbone of FRET biosensors for kinases and GTPases

(2011) Naoki Komatsu et al.   MOLECULAR BIOLOGY OF THE CELL

Stimulus-dependent dynamics of p53 in single cells

(2011) E. Batchelor et al.   Molecular Systems Biology

Global quantification of mammalian gene expression control

(2011) Björn Schwanhäusser et al.   NATURE

Single-cell NF-κB dynamics reveal digital activation and analogue information processing

(2010) Savaş Tay et al.   NATURE

Selective Signaling by Akt2 Promotes Bone Morphogenetic Protein 2-Mediated Osteoblast Differentiation

(2009) A. Mukherjee et al.   MOLECULAR AND CELLULAR BIOLOGY

Spatiotemporal Analysis of Differential Akt Regulation in Plasma Membrane Microdomains

(2008) Xinxin Gao et al.   MOLECULAR BIOLOGY OF THE CELL

Insulin-Like Growth Factor-Binding Protein-5 Inhibits Osteoblast Differentiation and Skeletal Growth by Blocking Insulin-Like Growth Factor Actions

(2008) Aditi Mukherjee et al.   MOLECULAR ENDOCRINOLOGY