Crystal Structure of CCM3, a Cerebral Cavernous Malformation Protein Critical for Vascular Integrity

Stabilization of VEGFR2 Signaling by Cerebral Cavernous Malformation 3 Is Critical for Vascular Development

(2010) Y. He et al.   Science Signaling

Crystal structures of free and ligand-bound focal adhesion targeting domain of Pyk2

(2009) James Lulo et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Control of cell adhesion dynamics by Rap1 signaling

(2009) Benjamin Boettner et al.   CURRENT OPINION IN CELL BIOLOGY

The cerebral cavernous malformation signaling pathway promotes vascular integrity via Rho GTPases

(2009) Kevin J Whitehead et al.   NATURE MEDICINE

HorA web server to infer homology between proteins using sequence and structural similarity

(2009) B.-H. Kim et al.   NUCLEIC ACIDS RESEARCH

A two-hit mechanism causes cerebral cavernous malformations: complete inactivation of CCM1, CCM2 or CCM3 in affected endothelial cells

(2008) Axel Pagenstecher et al.   HUMAN MOLECULAR GENETICS

Biallelic somatic and germline mutations in cerebral cavernous malformations (CCMs): evidence for a two-hit mechanism of CCM pathogenesis

(2008) Amy L. Akers et al.   HUMAN MOLECULAR GENETICS

Novel CCM1, CCM2, and CCM3 mutations in patients with cerebral cavernous malformations: in-frame deletion in CCM2 prevents formation of a CCM1/CCM2/CCM3 protein complex

(2008) Sonja Stahl et al.   HUMAN MUTATION