Hsc70 chaperone activity underlies Trio GEF function in axon growth and guidance induced by netrin-1

Regulation of cerebral cortex development by Rho GTPases: insights from in vivo studies

(2015) Roberta Azzarelli et al.   Frontiers in Cellular Neuroscience

Cell intrinsic control of axon regeneration

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Insights into the biological functions of Dock family guanine nucleotide exchange factors

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A novel Netrin-1–sensitive mechanism promotes local SNARE-mediated exocytosis during axon branching

(2014) Cortney C. Winkle et al.   JOURNAL OF CELL BIOLOGY

Netrin-DCC Signaling Regulates Corpus Callosum Formation Through Attraction of Pioneering Axons and by Modulating Slit2-Mediated Repulsion

(2013) Thomas Fothergill et al.   CEREBRAL CORTEX

Rho GTPases in neurodegeneration diseases

(2013) Jonathan DeGeer et al.   EXPERIMENTAL CELL RESEARCH

Plekhg4 Is a Novel Dbl Family Guanine Nucleotide Exchange Factor Protein for Rho Family GTPases

(2013) Meghana Gupta et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inhibition of Histone Deacetylase Activity Suppresses IFN-  Induction of Tripartite Motif 22 via CHIP-Mediated Proteasomal Degradation of IRF-1

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A Modified HSP70 Inhibitor Shows Broad Activity as an Anticancer Agent

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RAC1: An Emerging Therapeutic Option for Targeting Cancer Angiogenesis and Metastasis

(2013) H. K. Bid et al.   MOLECULAR CANCER THERAPEUTICS

Rho guanine nucleotide exchange factors: regulators of Rho GTPase activity in development and disease

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Amyloid Precursor Protein Regulates Netrin-1-mediated Commissural Axon Outgrowth

(2012) Nicolas Rama et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Tyrosine Phosphorylation of the Rho Guanine Nucleotide Exchange Factor Trio Regulates Netrin-1/DCC-Mediated Cortical Axon Outgrowth

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Association between schizophrenia and genetic variation in DCC: A case–control study

(2012) Alanna Grant et al.   SCHIZOPHRENIA RESEARCH

POSH Localizes Activated Rac1 to Control the Formation of Cytoplasmic Dilation of the Leading Process and Neuronal Migration

(2012) Tao Yang et al.   Cell Reports

Midline axon guidance and human genetic disorders

(2011) L Izzi et al.   CLINICAL GENETICS

Implication of Rho GTPases in Neurodegenerative Diseases

(2011) Judith Antoine-Bertrand et al.   CURRENT DRUG TARGETS

A Signaling Mechanism Coupling Netrin-1/Deleted in Colorectal Cancer Chemoattraction to SNARE-Mediated Exocytosis in Axonal Growth Cones

(2011) T. Cotrufo et al.   JOURNAL OF NEUROSCIENCE

Constitutive Upregulation of Chaperone-Mediated Autophagy in Huntington's Disease

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Molecular chaperones in protein folding and proteostasis

(2011) F. Ulrich Hartl et al.   NATURE

Endocytosis Regulates Cell Soma Translocation and the Distribution of Adhesion Proteins in Migrating Neurons

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Antileukemic activity of the HSP70 inhibitor pifithrin-μ in acute leukemia

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Nucleolar Targeting of the Chaperone Hsc70 Is Regulated by Stress, Cell Signaling, and a Composite Targeting Signal Which Is Controlled by Autoinhibition

(2010) Piotr Bański et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CSPα promotes SNARE-complex assembly by chaperoning SNAP-25 during synaptic activity

(2010) Manu Sharma et al.   NATURE CELL BIOLOGY

Mutations in DCC Cause Congenital Mirror Movements

(2010) M. Srour et al.   SCIENCE

Signaling from Axon Guidance Receptors

(2010) G. J. Bashaw et al.   Cold Spring Harbor Perspectives in Biology

Spatial and temporal activation of the small GTPases RhoA and Rac1 by the netrin-1 receptor UNC5a during neurite outgrowth

(2009) Mariêve Picard et al.   CELLULAR SIGNALLING

The trip of the tip: understanding the growth cone machinery

(2009) Laura Anne Lowery et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Sonic Hedgehog Guides Axons through a Noncanonical, Src-Family-Kinase-Dependent Signaling Pathway

(2009) Patricia T. Yam et al.   NEURON

DSCAM functions as a netrin receptor in commissural axon pathfinding

(2009) Guofa Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Membrane Fusion: Grappling with SNARE and SM Proteins

(2009) T. C. Sudhof et al.   SCIENCE

Axon guidance and synaptic maintenance: preclinical markers for neurodegenerative disease and therapeutics

(2009) Ling Lin et al.   TRENDS IN NEUROSCIENCES

DSCAM Is a Netrin Receptor that Collaborates with DCC in Mediating Turning Responses to Netrin-1

(2008) Alice Ly et al.   CELL

Rho inhibition recruits DCC to the neuronal plasma membrane and enhances axon chemoattraction to netrin 1

(2008) S. W. Moore et al.   DEVELOPMENT

Depolarization recruits DCC to the plasma membrane of embryonic cortical neurons and enhances axon extension in response to netrin-1

(2008) Jean-François Bouchard et al.   JOURNAL OF NEUROCHEMISTRY

Trio Mediates Netrin-1-Induced Rac1 Activation in Axon Outgrowth and Guidance

(2008) A. Briancon-Marjollet et al.   MOLECULAR AND CELLULAR BIOLOGY

Beyond Parkinson Disease: Amyotrophic Lateral Sclerosis and the Axon Guidance Pathway

(2008) Timothy G. Lesnick et al.   PLoS One