Article
Nanoscience & Nanotechnology
Nizan Kenane, Douglas A. Keszler
Summary: This study focuses on the impact of atmospheric gases on the dissolution rates of n-butyltin oxide hydroxide photoresists, revealing new phenomena such as the absorption of CO2 and reduction in carbon content. These findings may play a role in determining the patterning performance and variability based on changes in atmospheric gas composition.
ACS APPLIED MATERIALS & INTERFACES
(2021)
Article
Multidisciplinary Sciences
Qing Liu, Yiqin Chen, Zhanyong Feng, Zhiwen Shu, Huigao Duan
Summary: Resist nanokirigami is a novel lithography strategy that defines resist structures through selective mechanical peeling of unwanted resist film, without the need for exposure. It offers higher efficiency and the ability to fabricate multi-scale functional structures.
NATIONAL SCIENCE REVIEW
(2022)
Article
Chemistry, Multidisciplinary
Mohammad S. M. Saifullah, Mohamed Asbahi, Darren C. J. Neo, Zackaria Mahfoud, Hui Ru Tan, Son Tung Ha, Neeraj Dwivedi, Tanmay Dutta, Surani bin Dolmanan, Zainul Aabdin, Michel Bosman, Ramakrishnan Ganesan, Sudhiranjan Tripathy, David G. Hasko, Suresh Valiyaveettil
Summary: Research shows that with low-molecular-mass single-source precursor resists, high-resolution patterns that closely match the probe diameter of an electron beam lithography (EBL) system can be achieved. Energetic electrons enable top-down radiolysis and bottom-up construction of the resist, resulting in patterns with small features.
Article
Chemistry, Multidisciplinary
Mahdi Samadi Khoshkhoo, Anatol Prudnikau, Mohammad Reza Chashmejahanbin, Ralf Helbig, Vladimir Lesnyak, Gianaurelio Cuniberti
Summary: This work focuses on the multicolor patterning of two-dimensional nanoplatelets via self-assembly and direct electron-beam lithography, demonstrating successful fabrication of fluorescent nanoarrays. The fabricated micro/nanoarrays provide an innovative platform for investigating biological interactions and Forster resonance energy transfer.
Article
Chemistry, Physical
Christian D. Dieleman, Julia van der Burgt, Neha Thakur, Erik C. Garnett, Bruno Ehrler
Summary: Lead-halide perovskite (LHP) nanocrystals are an interesting material platform due to their easy synthesis and compositional versatility, allowing for tunable band gap and high photoluminescence quantum yield. Patterning colloidal LHP nanocrystals with electron-beam lithography can lead to more intricate designs and improve efficiencies. Despite some reduction in luminescent properties, this research represents a step towards patterning LHP nanocrystals at the nanoscale for device fabrication.
ACS APPLIED ENERGY MATERIALS
(2022)
Article
Nanoscience & Nanotechnology
Yihan Lu, Binbin Jin, Rui Zheng, Shan Wu, Ding Zhao, Min Qiu
Summary: In this study, it was discovered that aromatic molecules can be directly converted into nanostructures containing graphene quantum dots (GQDs) using cryogenic electron-beam writing, resulting in even red fluorescence emission. The photoluminescence intensity of the product can be easily controlled by adjusting the electron-beam exposure dose. Experimental analysis revealed a carbonization and graphitization process of the aromatic molecules during e-beam irradiation. This one-step method for production and patterning of GQDs enables their application in highly integrated and compact optoelectronic devices.
ACS APPLIED MATERIALS & INTERFACES
(2023)
Article
Chemistry, Multidisciplinary
Taewoo Ko, Samir Kumar, Sanghoon Shin, Dongmin Seo, Sungkyu Seo
Summary: In this study, a novel approach to pattern quantum dot (QD) nanopatterns by electron beam lithography was presented. Colloidal QDs were used without additional modifications, and reliable dot and line patterns with dimensions as small as 140 nm were successfully generated. Additionally, it was shown that using a SiO2 spacer layer on a Au substrate can significantly enhance the fluorescence intensity of QDs.
Article
Biotechnology & Applied Microbiology
Hang Zhou, Naoto Isozaki, Kazuya Fujimoto, Ryuji Yokokawa
Summary: This study provides plausible explanations for the discrepancies in the regulation of MT flexural rigidity and develops a new method for evaluating MT rigidity. Furthermore, it reveals a new relationship between the dynamics and mechanics of MTs, where MT flexural rigidity decreases through three phases with increasing growth rate. The growth rate-dependent flexural rigidity of MTs influences pattern formation in collective motion, which is validated using machine learning.
JOURNAL OF NANOBIOTECHNOLOGY
(2021)
Article
Nanoscience & Nanotechnology
Anshuman Cherala, Parth N. Pandya, Kenneth M. Liechti, S. V. Sreenivasan
Summary: Emerging nanoscale applications in energy, electronics, optics, and medicine can benefit from incorporating nanoshaped structures with sharp corners. By utilizing nanoimprint lithography followed by metal-assisted chemical etching, diamond-like nanoshapes have been shown to improve device performance. Studies suggest that scaling nanoshaped imprinting down to sub-10 nm levels is achievable with improved resist materials and novel bridge structures.
MICROSYSTEMS & NANOENGINEERING
(2021)
Article
Chemistry, Multidisciplinary
Eva De Leo, Aurelio A. Rossinelli, Patricia Marques-Gallego, Lisa V. Poulikakos, David J. Norris, Ferry Prins
Summary: Linear gratings patterned on the surface of cQD thin films enhance the outcoupling of emission, resulting in bright and saturated colors. By adjusting the periodicity and orientation of the gratings, active color tuning of the thin-film emission is achieved.
Article
Biophysics
Pattipong Wisanpitayakorn, Keith J. Mickolajczyk, William O. Hancock, Luis Vidali, Erkan Tuzel
Summary: Cytoskeletal filaments, such as microtubules and actin filaments, are crucial for maintaining the mechanical integrity of cells and their response to the environment. This study presents an alternative method for quantifying the deformations of biofilaments by measuring curvature distributions, and investigates the relationship between the apparent stiffness of filaments and the resolution and noise of the imaging system. The presented curvature analysis is more accurate than existing approaches for small data sets, and can be applied to both in vitro and in vivo filament data.
BIOPHYSICAL JOURNAL
(2022)
Article
Engineering, Electrical & Electronic
Midathala Yogesh, Mohamad G. Moinuddin, Manvendra Chauhan, Satinder K. Sharma, Subrata Ghosh, Kenneth E. Gonsalves
Summary: This study developed a polymeric resist for nanoscale patterning, demonstrating potential for forming 16 nm line/space features and successfully patterning 15 nm features. The resist has low weight-average molecular weight and good microstructural composition, showing sensitivity to both electron-beam and helium ion beam lithography.
ACS APPLIED ELECTRONIC MATERIALS
(2021)
Article
Chemistry, Multidisciplinary
Jose C. Mateus, Sean Weaver, Dirk van Swaay, Aline F. Renz, Julian Hengsteler, Paulo Aguiar, Janos Voeroes
Summary: This research utilizes electron beam lithography and photolithography to create microstructures that control neuronal connectivity, and demonstrates the formation of functional synapses in vitro.
Article
Chemistry, Multidisciplinary
Negar Gheshlaghi, Sina Foroutan-Barenji, Onur Erdem, Yemliha Altintas, Farzan Shabani, Muhammad Hamza Humayun, Hilmi Volkan Demir
Summary: The study presents the first account of self-resonant fully colloidal mu-lasers made from colloidal quantum well (CQW) solution. A deep patterning technique is developed to fabricate well-defined high aspect-ratio on-chip CQW resonators, allowing for in-plane lasing with tight optical confinement. The method is also successfully applied to various nanoparticles without affecting their physical and chemical properties.
Article
Nanoscience & Nanotechnology
Ahmad Chaker, Hayden R. Alty, Peng Tian, Anastasios Kotsovinos, Grigore A. Timco, Christopher A. Muryn, Scott M. Lewis, Richard E. P. Winpenny
Summary: This study demonstrates the nanoscale patterning of zinc oxide using electron beam lithography, achieving 12 nm zinc oxide lines with a 40 nm pitch on silicon. The chemical composition and properties transformation were analyzed using X-ray spectroscopy and electrical resistivity measurements, confirming the successful decomposition of zinc acetate into zinc oxide. The ZnO patterns were then utilized as a hard mask for silicon etching, showing good selectivity for the dry etching process.
ACS APPLIED NANO MATERIALS
(2021)
Article
Biophysics
Pattipong Wisanpitayakorn, Keith J. Mickolajczyk, William O. Hancock, Luis Vidali, Erkan Tuzel
Summary: Cytoskeletal filaments, such as microtubules and actin filaments, are crucial for maintaining the mechanical integrity of cells and their response to the environment. This study presents an alternative method for quantifying the deformations of biofilaments by measuring curvature distributions, and investigates the relationship between the apparent stiffness of filaments and the resolution and noise of the imaging system. The presented curvature analysis is more accurate than existing approaches for small data sets, and can be applied to both in vitro and in vivo filament data.
BIOPHYSICAL JOURNAL
(2022)
Article
Biology
Joseph M. Cleary, Tae Kim, Annan S. Cook, Lauren A. McCormick, William O. Hancock, Luke M. Rice, Thomas Surrey
Summary: Microtubule growth rates and fluctuations are influenced by the biochemical interactions of αβ-tubulin, with slower assembly kinetics and exposure of GDP-tubulin at the growing end being important factors in regulating microtubule dynamics and determining catastrophe.
Editorial Material
Biochemistry & Molecular Biology
William O. Hancock
Summary: A new study explores the transport and force-generating characteristics of KIF1C, a member of the kinesin-3 motor family. It reveals that KIF1C is more capable of sustaining loads compared to its sibling KIF1A, and that patient-derived mutants display significant defects in force generation.
Article
Cell Biology
April L. Solon, Taylor M. Zaniewski, Patrick O'Brien, Martin Clasby, William O. Hancock, Ryoma Ohi
Summary: This article investigates enhancing the cytotoxicity of K5 inhibitors by inhibiting KIF15. Through high-throughput screening, they identified two inhibitors that can inhibit the motor activity of KIF15 both in vitro and in cells, while also reducing the ability of cells to acquire resistance to K5 inhibitors.
MOLECULAR BIOLOGY OF THE CELL
(2022)
Article
Biology
Allison M. Gicking, Tzu-Chen Ma, Qingzhou Feng, Rui Jiang, Somayesadat Badieyan, Michael A. Cianfrocco, William O. Hancock
Summary: The study shows that kinesin-2 and -3 motors, despite being more sensitive to load, can effectively resist hindering loads generated by the dynein complex under experimental conditions; the similar performance between the three kinesin transport families highlights the critical role of motor kinetics in regulating the speed and directionality of cargo transport in cells.
Article
Biochemistry & Molecular Biology
Taylor M. Zaniewski, William O. Hancock
Summary: KIF1A is an essential neuronal transport motor protein in the kinesin-3 family that exhibits superprocessive motility. The superprocessivity of KIF1A dimers is determined by a unique structural domain called the 'K-loop', which enhances electrostatic interactions between the motor and the microtubule. The positive charge in loop-12 of KIF1A enhances the run length by stabilizing binding of the motor in its vulnerable one-head-bound state.
JOURNAL OF BIOLOGICAL CHEMISTRY
(2023)
Article
Multidisciplinary Sciences
Serapion Pyrpassopoulos, Allison M. Gicking, Taylor M. Zaniewski, William O. Hancock, E. Michael Ostap
Summary: KIF1A is a highly efficient vesicle transport motor that plays a role in neurodegenerative diseases. Optical tweezers were used to study its ability to generate force and sustain it against hindering loads. The results showed that KIF1A exhibits higher force and attachment duration in a three-bead assay compared to a single-bead assay. It was also found that KIF1A has a faster reengagement rate with microtubules after detachment compared to KIF5B. These findings provide insights into the adaptations of KIF1A in transport under load.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2023)
Article
Biophysics
Tzu-Chen Ma, Allison M. Gicking, Qingzhou Feng, William O. Hancock
Summary: This study used a stochastic stepping model to investigate the cooperation and competition of kinesin and dynein motors at the cellular level. The results showed that motor detachment events and reattachment rates have an impact on the speed and dynamics of bidirectional transport. These findings provide important hypotheses for future experiments.
BIOPHYSICAL JOURNAL
(2023)
Meeting Abstract
Biophysics
Allison M. Gicking, William O. Hancock
BIOPHYSICAL JOURNAL
(2022)
Meeting Abstract
Biophysics
Zachary K. Haviland, Daguan Nong, Kate Vasquez Kuntz, Thomas J. Starr, Dengbo Ma, Ming Tien, Charles T. Anderson, William O. Hancock
BIOPHYSICAL JOURNAL
(2022)
Meeting Abstract
Biophysics
Rui Jiang, Qingzhou Feng, Daguan Nong, You Jung Kang, William O. Hancock
BIOPHYSICAL JOURNAL
(2022)
Meeting Abstract
Biophysics
Daguan Nong, Zachary K. Haviland, Mikaela Mayers, Ming Tien, Charles T. Anderson, William O. Hancock
BIOPHYSICAL JOURNAL
(2022)
Meeting Abstract
Biophysics
Joseph M. Cleary, Tae Kim, Annan (Zeke) Cook, William O. Hancock, Luke M. Rice
BIOPHYSICAL JOURNAL
(2022)
Meeting Abstract
Biophysics
Taylor M. Zaniewski, William O. Hancock
BIOPHYSICAL JOURNAL
(2022)
Meeting Abstract
Biophysics
Taylor M. Zaniewski, Miranda L. Luque, William O. Hancock
BIOPHYSICAL JOURNAL
(2022)
