Comprehensive next-generation cancer genome sequencing in the era of targeted therapy and personalized oncology

The power of NGS technologies to delineate the genome organization in cancer: from mutations to structural variations and epigenetic alterations

(2011) Michal R. Schweiger et al.   CANCER AND METASTASIS REVIEWS

Identification of a Novel TP53 Cancer Susceptibility Mutation Through Whole-Genome Sequencing of a Patient With Therapy-Related AML

(2011) Daniel C. Link   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Use of Whole-Genome Sequencing to Diagnose a Cryptic Fusion Oncogene

(2011) John S. Welch   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Initial genome sequencing and analysis of multiple myeloma

(2011) Michael A. Chapman et al.   NATURE

The genomic complexity of primary human prostate cancer

(2011) Michael F. Berger et al.   NATURE

What’s new in non-small cell lung cancer for pathologists the importance of accurate subtyping, EGFR mutations and ALK rearrangements

(2011) Wendy A. Cooper et al.   PATHOLOGY

Detection and Removal of Biases in the Analysis of Next-Generation Sequencing Reads

(2011) Schraga Schwartz et al.   PLoS One

The Human Genome (Patent) Project

(2011) S. Kean   SCIENCE

Biomarker-Based Prediction of Response to Therapy for Colorectal Cancer

(2010) Jeffrey S. Ross et al.   AMERICAN JOURNAL OF CLINICAL PATHOLOGY

From genomic landscapes to personalized cancer management-is there a roadmap?

(2010) Charles Swanton et al.   Annals of the New York Academy of Sciences

Targeting KIT in melanoma: A paradigm of molecular medicine and targeted therapeutics

(2010) Scott E. Woodman et al.   BIOCHEMICAL PHARMACOLOGY

Challenges of sequencing human genomes

(2010) D. C. Koboldt et al.   BRIEFINGS IN BIOINFORMATICS

ALK Inhibition for Non-Small Cell Lung Cancer: From Discovery to Therapy in Record Time

(2010) David E. Gerber et al.   CANCER CELL

Driver mutations and differential sensitivity to targeted therapies: a new approach to the treatment of lung adenocarcinoma

(2010) Giuseppe Bronte et al.   CANCER TREATMENT REVIEWS

Clinical implications of KIT and PDGFRA genotyping in GIST

(2010) Javier Martín-Broto et al.   Clinical & Translational Oncology

Systematic comparison of three genomic enrichment methods for massively parallel DNA sequencing

(2010) J. K. Teer et al.   GENOME RESEARCH

Inherited Predisposition to Cancer: Introduction and Overview

(2010) Mark Robson et al.   HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA

Analysis of next-generation genomic data in cancer: accomplishments and challenges

(2010) L. Ding et al.   HUMAN MOLECULAR GENETICS

Clinical Implications of the Cancer Genome

(2010) Laura E. MacConaill et al.   JOURNAL OF CLINICAL ONCOLOGY

The GIST paradigm: lessons for other kinase-driven cancers

(2010) Cristina R Antonescu   JOURNAL OF PATHOLOGY

Rapid quantification of DNA libraries for next-generation sequencing

(2010) Bernd Buehler et al.   METHODS

Advances in understanding cancer genomes through second-generation sequencing

(2010) Matthew Meyerson et al.   NATURE REVIEWS GENETICS

Crizotinib — Latest Champion in the Cancer Wars?

(2010) Bengt Hallberg et al.   NEW ENGLAND JOURNAL OF MEDICINE

The Origin of the Haitian Cholera Outbreak Strain

(2010) Chen-Shan Chin et al.   NEW ENGLAND JOURNAL OF MEDICINE

A practical, bioinformatic workflow system for large data sets generated by next-generation sequencing

(2010) Cinzia Cantacessi et al.   NUCLEIC ACIDS RESEARCH

Prognostic and Predictive Biomarkers in Resected Colon Cancer: Current Status and Future Perspectives for Integrating Genomics into Biomarker Discovery

(2010) S. Tejpar et al.   ONCOLOGIST

Trastuzumab and beyond: sequencing cancer genomes and predicting molecular networks

(2010) D H Roukos   PHARMACOGENOMICS JOURNAL

Prognostic and predictive value of common mutations for treatment response and survival in patients with metastatic colorectal cancer

(2009) J Souglakos et al.   BRITISH JOURNAL OF CANCER

KRAS codon 61, 146 and BRAF mutations predict resistance to cetuximab plus irinotecan in KRAS codon 12 and 13 wild-type metastatic colorectal cancer

(2009) F Loupakis et al.   BRITISH JOURNAL OF CANCER

Next-Generation Sequencing: From Basic Research to Diagnostics

(2009) K. V. Voelkerding et al.   CLINICAL CHEMISTRY

Applications of Genomics in Melanoma Oncogene Discovery

(2009) Michael F. Berger et al.   HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA

Cancer genome sequencing: a review

(2009) E. R. Mardis et al.   HUMAN MOLECULAR GENETICS

KRAS Genotyping of Paraffin-Embedded Colorectal Cancer Tissue in Routine Diagnostics

(2009) Wilko Weichert et al.   JOURNAL OF MOLECULAR DIAGNOSTICS

Solution hybrid selection with ultra-long oligonucleotides for massively parallel targeted sequencing

(2009) Andreas Gnirke et al.   NATURE BIOTECHNOLOGY

Sequencing technologies — the next generation

(2009) Michael L. Metzker   NATURE REVIEWS GENETICS

Multi-Determinants Analysis of Molecular Alterations for Predicting Clinical Benefit to EGFR-Targeted Monoclonal Antibodies in Colorectal Cancer

(2009) Andrea Sartore-Bianchi et al.   PLoS One

Human Genome Sequencing Using Unchained Base Reads on Self-Assembling DNA Nanoarrays

(2009) R. Drmanac et al.   SCIENCE

Next-Generation DNA Sequencing Methods

(2008) Elaine R. Mardis   Annual Review of Genomics and Human Genetics

Pharmacogenomics of Tamoxifen and Irinotecan Therapies

(2008) Alicia Algeciras-Schimnich et al.   CLINICS IN LABORATORY MEDICINE

Wild-TypeBRAFIs Required for Response to Panitumumab or Cetuximab in Metastatic Colorectal Cancer

(2008) Federica Di Nicolantonio et al.   JOURNAL OF CLINICAL ONCOLOGY

A large genome center's improvements to the Illumina sequencing system

(2008) Michael A Quail et al.   NATURE METHODS

Alta-Cyclic: a self-optimizing base caller for next-generation sequencing

(2008) Yaniv Erlich et al.   NATURE METHODS

Real-Time DNA Sequencing from Single Polymerase Molecules

(2008) J. Eid et al.   SCIENCE