Is fat so bad? Modulation of endoplasmic reticulum stress by lipid droplet formation

Dietary Monounsaturated Fatty Acids Are Protective Against Metabolic Syndrome and Cardiovascular Disease Risk Factors

(2011) Leah G. Gillingham et al.   LIPIDS

Modulation of lipid droplet size and lipid droplet proteins by trans-10,cis-12 conjugated linoleic acid parallels improvements in hepatic steatosis in obese, insulin-resistant rats

(2010) Danielle M. Stringer et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

SnapShot: The Unfolded Protein Response

(2010) R. Luke Wiseman et al.   CELL

Quality and quantity control at the endoplasmic reticulum

(2010) Ramanujan S Hegde et al.   CURRENT OPINION IN CELL BIOLOGY

Interruption of triacylglycerol synthesis in the endoplasmic reticulum is the initiating event for saturated fatty acid-induced lipotoxicity in liver cells

(2010) Michalis D. Mantzaris et al.   FEBS Journal

Lipid-induced ER stress in yeast and β cells: parallel trails to a common fate

(2010) Ludovic Pineau et al.   FEMS YEAST RESEARCH

Oleate Inhibits Steryl Ester Synthesis and Causes Liposensitivity in Yeast

(2010) Melanie Connerth et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Sterol-induced Dislocation of 3-Hydroxy-3-methylglutaryl Coenzyme A Reductase from Endoplasmic Reticulum Membranes into the Cytosol through a Subcellular Compartment Resembling Lipid Droplets

(2010) Isamu Z. Hartman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Fatty acid-induced oxidation and triglyceride formation is higher in insulin-producing MIN6 cells exposed to oleate compared to palmitate

(2010) Kristofer Thörn et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Phospholipid demixing and the birth of a lipid droplet

(2010) J. Zanghellini et al.   JOURNAL OF THEORETICAL BIOLOGY

Polyunsaturated fatty acids synergize with lipid droplet binding thalidomide analogs to induce oxidative stress in cancer cells

(2010) László G Puskás et al.   Lipids in Health and Disease

Induction of Liver Steatosis and Lipid Droplet Formation in ATF6α-Knockout Mice Burdened with Pharmacological Endoplasmic Reticulum Stress

(2010) Keisuke Yamamoto et al.   MOLECULAR BIOLOGY OF THE CELL

Endoplasmic reticulum stress and atherosclerosis

(2010) Gökhan S Hotamisligil   NATURE MEDICINE

Obesity: stressing about unfolded proteins

(2010) Ronald C Wek et al.   NATURE MEDICINE

Modulation of Lipid-Induced ER Stress by Fatty Acid Shape

(2010) Julie Deguil et al.   TRAFFIC

Bcl-2 family on guard at the ER

(2009) Eva Szegezdi et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Diabetes and apoptosis: lipotoxicity

(2009) Christine M. Kusminski et al.   APOPTOSIS

Conditions of endoplasmic reticulum stress stimulate lipid droplet formation inSaccharomyces cerevisiae

(2009) Weihua Fei et al.   BIOCHEMICAL JOURNAL

SnapShot: Lipid Droplets

(2009) Natalie Krahmer et al.   CELL

IRE1α Kinase Activation Modes Control Alternate Endoribonuclease Outputs to Determine Divergent Cell Fates

(2009) Dan Han et al.   CELL

As a Matter of Fat

(2009) Rita T. Brookheart et al.   Cell Metabolism

α-Linolenic acid protects renal cells against palmitic acid lipotoxicity via inhibition of endoplasmic reticulum stress

(2009) Elias Katsoulieris et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Sterol and Diacylglycerol Acyltransferase Deficiency Triggers Fatty Acid-mediated Cell Death

(2009) Jeanne Garbarino et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Good Fat, Essential Cellular Requirements for Triacylglycerol Synthesis to Maintain Membrane Homeostasis in Yeast

(2009) Julia Petschnigg et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Effect of Lipid Particle Biogenesis on the Subcellular Distribution of Squalene in the Yeast Saccharomyces cerevisiae

(2009) Miroslava Spanova et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulated Ire1-dependent decay of messenger RNAs in mammalian cells

(2009) Julie Hollien et al.   JOURNAL OF CELL BIOLOGY

GRP78 expression inhibits insulin and ER stress–induced SREBP-1c activation and reduces hepatic steatosis in mice

(2009) Hélène L. Kammoun et al.   JOURNAL OF CLINICAL INVESTIGATION

Lipid droplet analysis in caveolin-deficient adipocytes: alterations in surface phospholipid composition and maturation defects

(2009) Cédric M. Blouin et al.   JOURNAL OF LIPID RESEARCH

Proteomic insights into an expanded cellular role for cytoplasmic lipid droplets

(2009) Brittany D. M. Hodges et al.   JOURNAL OF LIPID RESEARCH

Demonstrated and inferred metabolism associated with cytosolic lipid droplets: TABLE 1.

(2009) Joel M. Goodman   JOURNAL OF LIPID RESEARCH

Effect of intracellular lipid droplets on cytosolic Ca2+and cell death during ischaemia-reperfusion injury in cardiomyocytes

(2009) Ignasi Barba et al.   JOURNAL OF PHYSIOLOGY-LONDON

The Metabolic Syndrome

(2009) Matthew V. Potenza et al.   NUTRITION IN CLINICAL PRACTICE

Lipid-Induced ER Stress: Synergistic Effects of Sterols and Saturated Fatty Acids

(2009) Ludovic Pineau et al.   TRAFFIC

Differential regulation of the ER stress response by long-chain fatty acids in the pancreatic β-cell

(2008) Eleftheria Diakogiannaki et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

The cytoprotective actions of long-chain mono-unsaturated fatty acids in pancreatic β-cells

(2008) Noel G. Morgan et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Lipid droplet-organelle interactions; sharing the fats

(2008) Samantha Murphy et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

The life of lipid droplets

(2008) Tobias C. Walther et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Biogenesis of cytoplasmic lipid droplets: From the lipid ester globule in the membrane to the visible structure

(2008) Yuki Ohsaki et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Dissecting the ER-Associated Degradation of a Misfolded Polytopic Membrane Protein

(2008) Kunio Nakatsukasa et al.   CELL

Dephosphorylation of Translation Initiation Factor 2α Enhances Glucose Tolerance and Attenuates Hepatosteatosis in Mice

(2008) Seiichi Oyadomari et al.   Cell Metabolism

UPR Pathways Combine to Prevent Hepatic Steatosis Caused by ER Stress-Mediated Suppression of Transcriptional Master Regulators

(2008) D. Thomas Rutkowski et al.   DEVELOPMENTAL CELL

 -Cell Dysfunction in Subjects With Impaired Glucose Tolerance and Early Type 2 Diabetes: Comparison of Surrogate Markers With First-Phase Insulin Secretion From an Intravenous Glucose Tolerance Test

(2008) A. Festa et al.   DIABETES

A Block in Endoplasmic Reticulum-to-Golgi Trafficking Inhibits Phospholipid Synthesis and Induces Neutral Lipid Accumulation

(2008) Maria L. Gaspar et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural and Biochemical Properties of Lipid Particles from the YeastSaccharomyces cerevisiae

(2008) Tibor Czabany et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Fld1p, a functional homologue of human seipin, regulates the size of lipid droplets in yeast

(2008) Weihua Fei et al.   JOURNAL OF CELL BIOLOGY

Initiation and execution of lipotoxic ER stress in pancreatic  -cells

(2008) D. A. Cunha et al.   JOURNAL OF CELL SCIENCE

Inhibition of apolipoprotein B100 secretion by lipid-induced hepatic endoplasmic reticulum stress in rodents

(2008) Tsuguhito Ota et al.   JOURNAL OF CLINICAL INVESTIGATION

Functional genomic screen reveals genes involved in lipid-droplet formation and utilization

(2008) Yi Guo et al.   NATURE

Regulation of Hepatic Lipogenesis by the Transcription Factor XBP1

(2008) A.-H. Lee et al.   SCIENCE

The Recognition and Retrotranslocation of Misfolded Proteins from the Endoplasmic Reticulum

(2008) Kunio Nakatsukasa et al.   TRAFFIC