Journal
NATURE MEDICINE
Volume 16, Issue 4, Pages 374-376Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/nm0410-374
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Two reports in this issue identify a link between insulin action and the unfolded protein response-a pathway that helps the endoplasmic reticulum cope with cellular stress (pages 429-437 and 438-445). The results expand our understanding of the pathogenesis of insulin resistance and provide new targets for prevention and treatment of obesity.
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