Identification of transcription factors for drug-associated gene modules and biomedical implications

Characterization of drug-induced transcriptional modules: towards drug repositioning and functional understanding

(2013) M. Iskar et al.   Molecular Systems Biology

Reactive Oxygen Species via Redox Signaling to PI3K/AKT Pathway Contribute to the Malignant Growth of 4-Hydroxy Estradiol-Transformed Mammary Epithelial Cells

(2013) Victor O. Okoh et al.   PLoS One

Systematic Prediction of Pharmacodynamic Drug-Drug Interactions through Protein-Protein-Interaction Network

(2013) Jialiang Huang et al.   PLoS Computational Biology

Targeting Nrf2-Mediated Gene Transcription by Extremely Potent Synthetic Triterpenoids Attenuate Dopaminergic Neurotoxicity in the MPTP Mouse Model of Parkinson's Disease

(2012) Navneet Ammal Kaidery et al.   ANTIOXIDANTS & REDOX SIGNALING

Activation of nuclear factor erythroid 2-related factor 2 and PPARγ plays a role in the genistein-mediated attenuation of oxidative stress-induced endothelial cell injury

(2012) Ting Zhang et al.   BRITISH JOURNAL OF NUTRITION

Extensive Promoter-Centered Chromatin Interactions Provide a Topological Basis for Transcription Regulation

(2012) Guoliang Li et al.   CELL

Soy Isoflavones and Cardiovascular Disease Epidemiological, Clinical and -Omics Perspectives

(2012) A. Gil-Izquierdo et al.   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

STRING v9.1: protein-protein interaction networks, with increased coverage and integration

(2012) Andrea Franceschini et al.   NUCLEIC ACIDS RESEARCH

Tetradian oscillation of estrogen receptor   is necessary to prevent liver lipid deposition

(2012) A. Villa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Large-Scale Functional Organization of Long-Range Chromatin Interaction Networks

(2012) Kuljeet Singh Sandhu et al.   Cell Reports

Therapeutic target database update 2012: a resource for facilitating target-oriented drug discovery

(2011) F. Zhu et al.   NUCLEIC ACIDS RESEARCH

Participation of covalent modification of Keap1 in the activation of Nrf2 by tert-butylbenzoquinone, an electrophilic metabolite of butylated hydroxyanisole

(2011) Yumi Abiko et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

FABIA: factor analysis for bicluster acquisition

(2010) Sepp Hochreiter et al.   BIOINFORMATICS

Genome-Wide Analysis of Glucocorticoid Receptor Binding Regions in Adipocytes Reveal Gene Network Involved in Triglyceride Homeostasis

(2010) Chi-Yi Yu et al.   PLoS One

Discovery of drug mode of action and drug repositioning from transcriptional responses

(2010) F. Iorio et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Evolutionary inspirations for drug discovery

(2010) Hong-Yu Zhang et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Network-Based Elucidation of Human Disease Similarities Reveals Common Functional Modules Enriched for Pluripotent Drug Targets

(2010) Silpa Suthram et al.   PLoS Computational Biology

Report on the 8th International Symposium on the Role of Soy in Health Promotion and Chronic Disease Prevention and Treatment

(2009) Mark Messina et al.   JOURNAL OF NUTRITION

An oestrogen-receptor-α-bound human chromatin interactome

(2009) Melissa J. Fullwood et al.   NATURE

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

Bayesian biclustering of gene expression data

(2008) Jiajun Gu et al.   BMC GENOMICS

DrugBank and its relevance to pharmacogenomics

(2008) David S Wishart   PHARMACOGENOMICS