Characterization of drug-induced transcriptional modules: towards drug repositioning and functional understanding
Published 2013 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Characterization of drug-induced transcriptional modules: towards drug repositioning and functional understanding
Authors
Keywords
-
Journal
Molecular Systems Biology
Volume 9, Issue 1, Pages 662-662
Publisher
Wiley
Online
2013-04-30
DOI
10.1038/msb.2013.20
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- DvD: An R/Cytoscape pipeline for drug repurposing using public repositories of gene expression data
- (2012) Clare Pacini et al. BIOINFORMATICS
- Life in the Fast Lane: Mammalian Disease Models in the Genomics Era
- (2012) Lukas E. Dow et al. CELL
- The Role of Endoplasmic Reticulum in Hepatic Lipid Homeostasis and Stress Signaling
- (2012) Suneng Fu et al. Cell Metabolism
- Applications of Connectivity Map in drug discovery and development
- (2012) Xiaoyan A. Qu et al. DRUG DISCOVERY TODAY
- Transcriptional data: a new gateway to drug repositioning?
- (2012) Francesco Iorio et al. DRUG DISCOVERY TODAY
- Atypical antipsychotics alter cholesterol and fatty acid metabolism in vitro
- (2012) Alberto Canfrán-Duque et al. JOURNAL OF LIPID RESEARCH
- Systematic identification of genomic markers of drug sensitivity in cancer cells
- (2012) Mathew J. Garnett et al. NATURE
- The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity
- (2012) Jordi Barretina et al. NATURE
- Drug discovery in the age of systems biology: the rise of computational approaches for data integration
- (2011) Murat Iskar et al. CURRENT OPINION IN BIOTECHNOLOGY
- Combining Drug and Gene Similarity Measures for Drug-Target Elucidation
- (2011) Liat Perlman et al. JOURNAL OF COMPUTATIONAL BIOLOGY
- PREDICT: a method for inferring novel drug indications with application to personalized medicine
- (2011) A. Gottlieb et al. Molecular Systems Biology
- The evolution of gene expression levels in mammalian organs
- (2011) David Brawand et al. NATURE
- STITCH 3: zooming in on protein-chemical interactions
- (2011) M. Kuhn et al. NUCLEIC ACIDS RESEARCH
- Database resources of the National Center for Biotechnology Information
- (2011) E. W. Sayers et al. NUCLEIC ACIDS RESEARCH
- KEGG for integration and interpretation of large-scale molecular data sets
- (2011) M. Kanehisa et al. NUCLEIC ACIDS RESEARCH
- Computational Repositioning of the Anticonvulsant Topiramate for Inflammatory Bowel Disease
- (2011) J. T. Dudley et al. Science Translational Medicine
- Discovery and Preclinical Validation of Drug Indications Using Compendia of Public Gene Expression Data
- (2011) M. Sirota et al. Science Translational Medicine
- Using Transcription Modules to Identify Expression Clusters Perturbed in Williams-Beuren Syndrome
- (2011) Charlotte N. Henrichsen et al. PLoS Computational Biology
- Large scale comparison of global gene expression patterns in human and mouse
- (2011) Xiangqun Zheng-Bradley et al. GENOME BIOLOGY
- The similarity of gene expression between human and mouse tissues
- (2011) Robin D Dowell GENOME BIOLOGY
- Modular analysis of gene expression data with R
- (2010) G. Csardi et al. BIOINFORMATICS
- Interaction of β-Carboline Alkaloids with RNA
- (2010) Shohreh Nafisi et al. DNA AND CELL BIOLOGY
- A side effect resource to capture phenotypic effects of drugs
- (2010) Michael Kuhn et al. Molecular Systems Biology
- The STRING database in 2011: functional interaction networks of proteins, globally integrated and scored
- (2010) D. Szklarczyk et al. NUCLEIC ACIDS RESEARCH
- Divergence of human and mouse brain transcriptome highlights Alzheimer disease pathways
- (2010) Jeremy A. Miller et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Discovery of drug mode of action and drug repositioning from transcriptional responses
- (2010) F. Iorio et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Evolution of Bioinformatics in Toxicology: Advancing Toxicogenomics
- (2010) C. A. Afshari et al. TOXICOLOGICAL SCIENCES
- Drug-Induced Regulation of Target Expression
- (2010) Murat Iskar et al. PLoS Computational Biology
- Identification of Cholesterol-Regulating Genes by Targeted RNAi Screening
- (2009) Fabian Bartz et al. Cell Metabolism
- Identifying Network of Drug Mode of Action by Gene Expression Profiling
- (2009) Francesco Iorio et al. JOURNAL OF COMPUTATIONAL BIOLOGY
- Predicting new molecular targets for known drugs
- (2009) Michael J. Keiser et al. NATURE
- Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources
- (2009) Da Wei Huang et al. Nature Protocols
- Multi-parameter phenotypic profiling: using cellular effects to characterize small-molecule compounds
- (2009) Yan Feng et al. NATURE REVIEWS DRUG DISCOVERY
- Antipsychotic drugs upregulate lipogenic gene expression by disrupting intracellular trafficking of lipoprotein-derived cholesterol
- (2009) I Kristiana et al. PHARMACOGENOMICS JOURNAL
- Human Disease-Drug Network Based on Genomic Expression Profiles
- (2009) Guanghui Hu et al. PLoS One
- Prediction of Pharmacological and Xenobiotic Responses to Drugs Based on Time Course Gene Expression Profiles
- (2009) Tao Huang et al. PLoS One
- WGCNA: an R package for weighted correlation network analysis
- (2008) Peter Langfelder et al. BMC BIOINFORMATICS
- Cholesterol feedback: from Schoenheimer's bottle to Scap's MELADL
- (2008) Michael S. Brown et al. JOURNAL OF LIPID RESEARCH
- The liver pharmacological and xenobiotic gene response repertoire
- (2008) Georges Natsoulis et al. Molecular Systems Biology
- A modular approach for integrative analysis of large-scale gene-expression and drug-response data
- (2008) Zoltán Kutalik et al. NATURE BIOTECHNOLOGY
- Functional organization of the transcriptome in human brain
- (2008) Michael C Oldham et al. NATURE NEUROSCIENCE
- Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists
- (2008) Da Wei Huang et al. NUCLEIC ACIDS RESEARCH
- Drug Target Identification Using Side-Effect Similarity
- (2008) M. Campillos et al. SCIENCE
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now