Repurposing of gallium-based drugs for antibacterial therapy

Initial phase I clinical and pharmacokinetic assessment of G4544, an oral gallium-containing compound

(2017) S. C. Novick et al.   JOURNAL OF CLINICAL ONCOLOGY

Promises and failures of gallium as an antibacterial agent

(2014) Fabrizia Minandri et al.   Future Microbiology

The Dual Personality of Iron Chelators: Growth Inhibitors or Promoters?

(2013) Paolo Visca et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Gallium Nitrate Is Efficacious in Murine Models of Tuberculosis and Inhibits Key Bacterial Fe-Dependent Enzymes

(2013) Oyebode Olakanmi et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Gallium-based anti-infectives: targeting microbial iron-uptake mechanisms

(2013) Andrew B Kelson et al.   CURRENT OPINION IN PHARMACOLOGY

Emerging drugs on methicillin-resistantStaphylococcus aureus

(2013) Adamantia Liapikou et al.   EXPERT OPINION ON EMERGING DRUGS

FeoB-Mediated Uptake of Iron by Francisella tularensis

(2013) Cindy A. Thomas-Charles et al.   INFECTION AND IMMUNITY

Isolation and characterization of gallium resistant Pseudomonas aeruginosa mutants

(2013) Rodolfo García-Contreras et al.   INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY

Repurposing the antimycotic drug flucytosine for suppression of Pseudomonas aeruginosa pathogenicity

(2013) F. Imperi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Discovery of a Siderophore Export System Essential for Virulence of Mycobacterium tuberculosis

(2013) Ryan M. Wells et al.   PLoS Pathogens

Gallium induces the production of virulence factors inPseudomonas aeruginosa

(2013) Rodolfo García-Contreras et al.   Pathogens and Disease

Hepatocellular Carcinoma Detection by Gallium Scan and Subsequent Treatment by Gallium Maltolate: Rationale and Case Study

(2012) Lawrence R. Bernstein et al.   Anti-Cancer Agents in Medicinal Chemistry

In VitroandIn VivoAntimicrobial Activities of Gallium Nitrate against Multidrug-Resistant Acinetobacter baumannii

(2012) Luísa C. S. Antunes et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

In VitroandIn VivoBiological Activities of Iron Chelators and Gallium Nitrate against Acinetobacter baumannii

(2012) Louis de Léséleuc et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Gallium as a potential candidate for treatment of osteoporosis

(2012) E. Verron et al.   DRUG DISCOVERY TODAY

Targeting iron assimilation to develop new antibacterials

(2012) Timothy L Foley et al.   Expert Opinion on Drug Discovery

Novel therapeutic strategies to counterPseudomonas aeruginosainfections

(2012) Joanne L Fothergill et al.   Expert Review of Anti-Infective Therapy

The Hydroxamate Siderophore Rhequichelin Is Required for Virulence of the Pathogenic Actinomycete Rhodococcus equi

(2012) Raúl Miranda-CasoLuengo et al.   INFECTION AND IMMUNITY

Gallium complexes as new promising metallodrug candidates

(2012) Josane A. Lessa et al.   INORGANICA CHIMICA ACTA

Treatment of lung infection in patients with cystic fibrosis: Current and future strategies

(2012) Gerd Döring et al.   Journal of Cystic Fibrosis

Evaluation of the in vitro activity of gallium nitrate againstMycobacterium aviumsubspparatuberculosis

(2011) Marie-Eve Fecteau et al.   AMERICAN JOURNAL OF VETERINARY RESEARCH

The Antibacterial Activity of Ga3+Is Influenced by Ligand Complexation as Well as the Bacterial Carbon Source

(2011) Olena Rzhepishevska et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Combating biofilms

(2011) Liang Yang et al.   FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY

Redundancy and Specificity ofEscherichia coliIron Acquisition Systems during Urinary Tract Infection

(2011) Erin C. Garcia et al.   INFECTION AND IMMUNITY

Antimicrobial Activity of Gallium Nitrate against Mycobacterium avium subsp. paratuberculosis in Neonatal Calves

(2011) M.-E. Fecteau et al.   JOURNAL OF VETERINARY INTERNAL MEDICINE

Antimicrobial activity of gallium maltolate against Staphylococcus aureus and methicillin-resistant S. aureus and Staphylococcus pseudintermedius: An in vitro study

(2011) Carolyn E. Arnold et al.   VETERINARY MICROBIOLOGY

The clinical impact of bacterial biofilms

(2011) Niels Høiby et al.   International Journal of Oral Science

The Yersiniabactin Transport System Is Critical for the Pathogenesis of Bubonic and Pneumonic Plague

(2010) J. D. Fetherston et al.   INFECTION AND IMMUNITY

Clinical outcomes of health-care-associated infections and antimicrobial resistance in patients admitted to European intensive-care units: a cohort study

(2010) Marie-Laurence Lambert et al.   LANCET INFECTIOUS DISEASES

Chemistry and biology of siderophores

(2010) Robert C. Hider et al.   NATURAL PRODUCT REPORTS

In vitro antimicrobial activity of gallium maltolate against virulent Rhodococcus equi

(2010) Michelle Coleman et al.   VETERINARY MICROBIOLOGY

Gallium Maltolate Treatment Eradicates Pseudomonas aeruginosa Infection in Thermally Injured Mice

(2009) K. DeLeon et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

In Vitro Activity of Gallium Maltolate against Staphylococci in Logarithmic, Stationary, and Biofilm Growth Phases: Comparison of Conventional and Calorimetric Susceptibility Testing Methods

(2009) D. Baldoni et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Gallium Disrupts Iron Uptake by Intracellular and Extracellular Francisella Strains and Exhibits Therapeutic Efficacy in a Murine Pulmonary Infection Model

(2009) O. Olakanmi et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Siderophores as drug delivery agents: application of the “Trojan Horse” strategy

(2009) Ute Möllmann et al.   BIOMETALS

New insights into the metal specificity of thePseudomonas aeruginosapyoverdine-iron uptake pathway

(2009) Armelle Braud et al.   ENVIRONMENTAL MICROBIOLOGY

The Pseudomonas aeruginosa Pyochelin-Iron Uptake Pathway and Its Metal Specificity

(2009) A. Braud et al.   JOURNAL OF BACTERIOLOGY

The gallium complex KP46 exerts strong activity against primary explanted melanoma cells and induces apoptosis in melanoma cell lines

(2009) Seied Mojtaba Valiahdi et al.   MELANOMA RESEARCH

Citrate-mediated iron uptake in Pseudomonas aeruginosa: involvement of the citrate-inducible FecA receptor and the FeoB ferrous iron transporter

(2009) B. Marshall et al.   MICROBIOLOGY-SGM

Burkholderia cepaciaComplex: Impact on the Cystic Fibrosis Lung Lesion

(2009) Joseph Lynch   SEMINARS IN RESPIRATORY AND CRITICAL CARE MEDICINE

Iron availability and infection

(2008) Eugene D. Weinberg   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Resistance of planktonic and biofilm-grown Burkholderia cepacia complex isolates to the transition metal gallium

(2008) E. Peeters et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

The potential of desferrioxamine-gallium as an anti-Pseudomonas therapeutic agent

(2008) E. Banin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural biology of bacterial iron uptake

(2007) Karla D. Krewulak et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES