Endocannabinoids and energy homeostasis: An update

The endocannabinoid system controls food intake via olfactory processes

(2014) Edgar Soria-Gómez et al.   NATURE NEUROSCIENCE

Presynaptic Leptin Action Suppresses Excitatory Synaptic Transmission onto Ventral Tegmental Area Dopamine Neurons

(2013) Jennifer L. Thompson et al.   BIOLOGICAL PSYCHIATRY

The Endocannabinoid System in Energy Homeostasis and the Etiopathology of Metabolic Disorders

(2013) Cristoforo Silvestri et al.   Cell Metabolism

The CB1 receptor mediates the peripheral effects of ghrelin on AMPK activity but not on growth hormone release

(2013) Blerina Kola et al.   FASEB JOURNAL

Hepatic cannabinoid-1 receptors mediate diet-induced insulin resistance by increasingde novosynthesis of long-chain ceramides

(2013) Resat Cinar et al.   HEPATOLOGY

CB1Cannabinoid Receptors Couple to Focal Adhesion Kinase to Control Insulin Release

(2013) Katarzyna Malenczyk et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Activation of the Nlrp3 inflammasome in infiltrating macrophages by endocannabinoids mediates beta cell loss in type 2 diabetes

(2013) Tony Jourdan et al.   NATURE MEDICINE

Insulin induces long-term depression of ventral tegmental area dopamine neurons via endocannabinoids

(2013) Gwenaël Labouèbe et al.   NATURE NEUROSCIENCE

Activation of the sympathetic nervous system mediates hypophagic and anxiety-like effects of CB1 receptor blockade

(2013) L. Bellocchio et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Obesity-driven synaptic remodeling affects endocannabinoid control of orexinergic neurons

(2013) L. Cristino et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Monounsaturated fatty acids generated via stearoyl CoA desaturase-1 are endogenous inhibitors of fatty acid amide hydrolase

(2013) J. Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A novel fluorophosphonate inhibitor of the biosynthesis of the endocannabinoid 2-arachidonoylglycerol with potential anti-obesity effects

(2012) Tiziana Bisogno et al.   BRITISH JOURNAL OF PHARMACOLOGY

2-Arachidonoylglycerol Signaling in Forebrain Regulates Systemic Energy Metabolism

(2012) Kwang-Mook Jung et al.   Cell Metabolism

Peripheral Cannabinoid-1 Receptor Inverse Agonism Reduces Obesity by Reversing Leptin Resistance

(2012) Joseph Tam et al.   Cell Metabolism

Hypothalamic CB1 Cannabinoid Receptors Regulate Energy Balance in Mice

(2012) Pierre Cardinal et al.   ENDOCRINOLOGY

Cannabinoid-1 receptor (CB1R) blockers as medicines: beyond obesity and cardiometabolic disorders to substance abuse/drug addiction with CB1R neutral antagonists

(2012) David R. Janero   EXPERT OPINION ON EMERGING DRUGS

Hedonic Eating Is Associated with Increased Peripheral Levels of Ghrelin and the Endocannabinoid 2-Arachidonoyl-Glycerol in Healthy Humans: A Pilot Study

(2012) Palmiero Monteleone et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Role of sex hormones in modulation of brown adipose tissue activity

(2012) Carmelo Quarta et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

Cannabinoids Inhibit Insulin Receptor Signaling in Pancreatic  -Cells

(2011) W. Kim et al.   DIABETES

Cannabinoid receptor 1 (CB1) antagonism enhances glucose utilisation and activates brown adipose tissue in diet-induced obese mice

(2011) M. Bajzer et al.   DIABETOLOGIA

CNS Opioid Signaling Separates Cannabinoid Receptor 1-Mediated Effects on Body Weight and Mood-Related Behavior in Mice

(2011) Sarah Haas Lockie et al.   ENDOCRINOLOGY

The role of the endocannabinoid system in the neuroendocrine regulation of energy balance

(2011) Francisco Javier Bermudez-Silva et al.   JOURNAL OF PSYCHOPHARMACOLOGY

Endocannabinoids Gate State-Dependent Plasticity of Synaptic Inhibition in Feeding Circuits

(2011) Karen M. Crosby et al.   NEURON

Cannabinoid facilitation of behavioral and biochemical hedonic taste responses

(2011) M.A. De Luca et al.   NEUROPHARMACOLOGY

The intricate link between glucocorticoids and endocannabinoids at stress-relevant synapses in the hypothalamus

(2011) K.M. Crosby et al.   NEUROSCIENCE

Rimonabant Redux and Strategies to Improve the Future Outlook of CB1 Receptor Neutral-Antagonist/Inverse-Agonist Therapies

(2011) Sara Jane Ward et al.   Obesity

The Central Cannabinoid CB1 Receptor Is Required for Diet-Induced Obesity and Rimonabant's Antiobesity Effects in Mice

(2011) Zhen Pang et al.   Obesity

Erk1/2 Mediates Leptin Receptor Signaling in the Ventral Tegmental Area

(2011) Richard Trinko et al.   PLoS One

Steroidogenic factor 1 directs programs regulating diet-induced thermogenesis and leptin action in the ventral medial hypothalamic nucleus

(2011) K. W. Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Endocannabinoid signal in the gut controls dietary fat intake

(2011) N. V. DiPatrizio et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Peripheral effects of the endocannabinoid system in energy homeostasis: Adipose tissue, liver and skeletal muscle

(2011) Cristoforo Silvestri et al.   REVIEWS IN ENDOCRINE & METABOLIC DISORDERS

Cannabinoid type 1 receptor mediates depot-specific effects on differentiation, inflammation and oxidative metabolism in inguinal and epididymal white adipocytes

(2011) I V Wagner et al.   Nutrition & Diabetes

CB1 Signaling in Forebrain and Sympathetic Neurons Is a Key Determinant of Endocannabinoid Actions on Energy Balance

(2010) Carmelo Quarta et al.   Cell Metabolism

Effects of in vitro antagonism of endocannabinoid-1 receptors on the glucose transport system in normal and insulin-resistant rat skeletal muscle

(2010) K. A. Lindborg et al.   DIABETES OBESITY & METABOLISM

Peripheral CB1 cannabinoid receptor blockade improves cardiometabolic risk in mouse models of obesity

(2010) Joseph Tam et al.   JOURNAL OF CLINICAL INVESTIGATION

An overview of the metabolic effects of rimonabant in randomized controlled trials: potential for other cannabinoid 1 receptor blockers in obesity

(2010) F. D. Christopoulou et al.   JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS

The Endocannabinoid 2-Arachidonoyl-Glycerol Controls Odor Sensitivity in Larvae of Xenopus laevis

(2010) E. Breunig et al.   JOURNAL OF NEUROSCIENCE

The endocannabinoid system links gut microbiota to adipogenesis

(2010) Giulio G Muccioli et al.   Molecular Systems Biology

Bimodal control of stimulated food intake by the endocannabinoid system

(2010) Luigi Bellocchio et al.   NATURE NEUROSCIENCE

Endocannabinoid signaling in the brain: biosynthetic mechanisms in the limelight

(2010) Vincenzo Di Marzo   NATURE NEUROSCIENCE

Role of the endocannabinoid system in food intake, energy homeostasis and regulation of the endocrine pancreas

(2010) Chen Li et al.   PHARMACOLOGY & THERAPEUTICS

The role of the pancreatic endocannabinoid system in glucose metabolism

(2009) Francisco J. Bermúdez-Silva et al.   BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM

Synthesis and Pharmacological Activity of a Potent Inhibitor of the Biosynthesis of the Endocannabinoid 2-Arachidonoylglycerol

(2009) Tiziana Bisogno et al.   ChemMedChem

Regulation of MAP Kinase-Directed Mitogenic and Protein Kinase B-Mediated Signaling by Cannabinoid Receptor Type 1 in Skeletal Muscle Cells

(2009) C. Lipina et al.   DIABETES

Cannabinoid type 1 receptor blockade induces transdifferentiation towards a brown fat phenotype in white adipocytes

(2009) N. Perwitz et al.   DIABETES OBESITY & METABOLISM

Beneficial effect of a chronic treatment with rimonabant on pancreatic function and β-cell morphology in Zucker Fatty rats

(2009) Valérie F. Duvivier et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

The endocannabinoid system as a link between homoeostatic and hedonic pathways involved in energy balance regulation

(2009) V Di Marzo et al.   INTERNATIONAL JOURNAL OF OBESITY

CB1 antagonists for obesity—what lessons have we learned from rimonabant?

(2009) Vincenzo Di Marzo et al.   Nature Reviews Endocrinology

The CB1 Antagonist Rimonabant Decreases Insulin Hypersecretion in Rat Pancreatic Islets

(2009) Lisa Getty-Kaushik et al.   Obesity

Endocannabinoid-Mediated Control of Synaptic Transmission

(2009) Masanobu Kano et al.   PHYSIOLOGICAL REVIEWS

Increased Energy Expenditure Contributes More to the Body Weight-Reducing Effect of Rimonabant than Reduced Food Intake in Candy-Fed Wistar Rats

(2008) Andreas W. Herling et al.   ENDOCRINOLOGY

Hepatic CB1 receptor is required for development of diet-induced steatosis, dyslipidemia, and insulin and leptin resistance in mice

(2008) Douglas Osei-Hyiaman et al.   JOURNAL OF CLINICAL INVESTIGATION

Cholecystokinin Regulates Expression of Y2 Receptors in Vagal Afferent Neurons Serving the Stomach

(2008) G. Burdyga et al.   JOURNAL OF NEUROSCIENCE

Leptin controls adipose tissue lipogenesis via central, STAT3–independent mechanisms

(2008) Christoph Buettner et al.   NATURE MEDICINE

Neurobiology of Nutrition and Obesity

(2008) Christopher D. Morrison et al.   NUTRITION REVIEWS

Effects of acute low-dose combined treatment with naloxone and AM 251 on food intake, feeding behaviour and weight gain in rats

(2008) A.J. Tallett et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

The Orexigenic Effect of Ghrelin Is Mediated through Central Activation of the Endogenous Cannabinoid System

(2008) Blerina Kola et al.   PLoS One

Reward-Predictive Cues Enhance Excitatory Synaptic Strength onto Midbrain Dopamine Neurons

(2008) G. D. Stuber et al.   SCIENCE