CB1Cannabinoid Receptors Couple to Focal Adhesion Kinase to Control Insulin Release

The Endocannabinoid System in Energy Homeostasis and the Etiopathology of Metabolic Disorders

(2013) Cristoforo Silvestri et al.   Cell Metabolism

CB1 cannabinoid receptors promote maximal FAK catalytic activity by stimulating cooperative signaling between receptor tyrosine kinases and integrins in neuronal cells

(2013) George D. Dalton et al.   CELLULAR SIGNALLING

Non-muscle myosin IIA is involved in focal adhesion and actin remodelling controlling glucose-stimulated insulin secretion

(2013) C. Arous et al.   DIABETOLOGIA

Nerve growth factor scales endocannabinoid signaling by regulating monoacylglycerol lipase turnover in developing cholinergic neurons

(2013) E. Keimpema et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Diacylglycerol lipase α manipulation reveals developmental roles for intercellular endocannabinoid signaling

(2013) Erik Keimpema et al.   Scientific Reports

Chronic activation of cannabinoid receptorsin vitrodoes not compromise mouse islet function

(2012) Alonso Vilches-Flores et al.   CLINICAL SCIENCE

In Vivo Role of Focal Adhesion Kinase in Regulating Pancreatic  -Cell Mass and Function Through Insulin Signaling, Actin Dynamics, and Granule Trafficking

(2012) E. P. Cai et al.   DIABETES

Akt1 promotes focal adhesion disassembly and cell motility through phosphorylation of FAK in growth factor-stimulated cells

(2012) M. Higuchi et al.   JOURNAL OF CELL SCIENCE

Why do cannabinoid receptors have more than one endogenous ligand?

(2012) V. Di Marzo et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Endocannabinoids Measurement in Human Saliva as Potential Biomarker of Obesity

(2012) Isabelle Matias et al.   PLoS One

Cannabinoids Induce Pancreatic  -Cell Death by Directly Inhibiting Insulin Receptor Activation

(2012) W. Kim et al.   Science Signaling

Molecular reorganization of endocannabinoid signalling in Alzheimer’s disease

(2011) Jan Mulder et al.   BRAIN

Focal Adhesion Remodeling Is Crucial for Glucose-Stimulated Insulin Secretion and Involves Activation of Focal Adhesion Kinase and Paxillin

(2011) D. Rondas et al.   DIABETES

Cyclin-Dependent Kinase 5 Promotes Pancreatic  -Cell Survival via Fak-Akt Signaling Pathways

(2011) M. Daval et al.   DIABETES

Cannabinoid Receptor Type 1 (CB1) Activation Inhibits Small GTPase RhoA Activity and Regulates Motility of Prostate Carcinoma Cells

(2011) Kasem Nithipatikom et al.   ENDOCRINOLOGY

Disruption and stabilization of β-cell actin microfilaments differently influence insulin secretion triggered by intracellular Ca2+mobilization or store-operated Ca2+entry

(2011) Jean-Claude Henquin et al.   FEBS LETTERS

Novel Mechanistic Link between Focal Adhesion Remodeling and Glucose-stimulated Insulin Secretion

(2011) Dieter Rondas et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lysophosphatidylinositol Causes Neurite Retraction via GPR55, G13 and RhoA in PC12 Cells

(2011) Yutaro Obara et al.   PLoS One

Effects of F/G-actin ratio and actin turn-over rate on NADPH oxidase activity in microglia

(2010) Izabela Rasmussen et al.   BMC IMMUNOLOGY

Cannabinoid Receptors are Coupled to Stimulation of Insulin Secretion from Mouse MIN6 β-cells

(2010) Chen Li et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Loss of Retrograde Endocannabinoid Signaling and Reduced Adult Neurogenesis in Diacylglycerol Lipase Knock-out Mice

(2010) Y. Gao et al.   JOURNAL OF NEUROSCIENCE

Chronic monoacylglycerol lipase blockade causes functional antagonism of the endocannabinoid system

(2010) Joel E Schlosburg et al.   NATURE NEUROSCIENCE

CB1 cannabinoid receptor expression is regulated by glucose and feeding in rat pancreatic islets

(2010) Alonso Vilches-Flores et al.   REGULATORY PEPTIDES

Monoacylglycerol Lipase Regulates a Fatty Acid Network that Promotes Cancer Pathogenesis

(2009) Daniel K. Nomura et al.   CELL

β1 integrin/FAK/ERK signalling pathway is essential for human fetal islet cell differentiation and survival

(2009) Saira Saleem et al.   JOURNAL OF PATHOLOGY

The CB1 Antagonist Rimonabant Decreases Insulin Hypersecretion in Rat Pancreatic Islets

(2009) Lisa Getty-Kaushik et al.   Obesity

Endocannabinoid-Mediated Control of Synaptic Transmission

(2009) Masanobu Kano et al.   PHYSIOLOGICAL REVIEWS

CAY10499, a Novel Monoglyceride Lipase Inhibitor Evidenced by an Expeditious MGL Assay

(2008) Giulio G. Muccioli et al.   CHEMBIOCHEM

The endocannabinoid system in obesity and type 2 diabetes

(2008) V. Di Marzo   DIABETOLOGIA

The anandamide analog, Met-F-AEA, controls human breast cancer cell migration via the RHOA/RHO kinase signaling pathway

(2008) C. Laezza et al.   ENDOCRINE-RELATED CANCER

Filamentous Actin Regulates Insulin Exocytosis through Direct Interaction with Syntaxin 4

(2008) Jenna L. Jewell et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Endocannabinoids and the Control of Energy Homeostasis

(2008) George Kunos et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Anandamide Biosynthesis Catalyzed by the Phosphodiesterase GDE1 and Detection of Glycerophospho-N-acyl Ethanolamine Precursors in Mouse Brain

(2008) Gabriel M. Simon et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Small Molecule Inhibitor, 1,2,4,5-Benzenetetraamine Tetrahydrochloride, Targeting the Y397 Site of Focal Adhesion Kinase Decreases Tumor Growth

(2008) Vita M. Golubovskaya et al.   JOURNAL OF MEDICINAL CHEMISTRY

Tetrahydrolipstatin Analogues as Modulators of Endocannabinoid 2-Arachidonoylglycerol Metabolism

(2008) Giorgio Ortar et al.   JOURNAL OF MEDICINAL CHEMISTRY

In vivoinhibition of focal adhesion kinase causes insulin resistance

(2008) Bharti Bisht et al.   JOURNAL OF PHYSIOLOGY-LONDON

Selective blockade of 2-arachidonoylglycerol hydrolysis produces cannabinoid behavioral effects

(2008) Jonathan Z Long et al.   Nature Chemical Biology

Endocannabinoid Dysregulation in the Pancreas and Adipose Tissue of Mice Fed With a High-fat Diet

(2008) Katarzyna M. Starowicz et al.   Obesity

The orphan receptor GPR55 is a novel cannabinoid receptor

(2007) E Ryberg et al.   BRITISH JOURNAL OF PHARMACOLOGY

Immunohistochemical localization of anabolic and catabolic enzymes for anandamide and other putative endovanilloids in the hippocampus and cerebellar cortex of the mouse brain

(2007) L. Cristino et al.   NEUROSCIENCE

Cannabinoids inhibit insulin secretion and cytosolic Ca2+ oscillation in islet β-cells via CB1 receptors

(2007) Masanori Nakata et al.   REGULATORY PEPTIDES