The emerging roles of inositol pyrophosphates in eukaryotic cell physiology

Inositol pyrophosphates regulate RNA polymerase I-mediated rRNA transcription inSaccharomyces cerevisiae

(2015) Swarna Gowri Thota et al.   BIOCHEMICAL JOURNAL

Establishing the Stability and Reversibility of Protein Pyrophosphorylation with Synthetic Peptides

(2015) Lisa M. Yates et al.   CHEMBIOCHEM

VIH2 Regulates the Synthesis of Inositol Pyrophosphate InsP8and Jasmonate-Dependent Defenses in Arabidopsis

(2015) Debabrata Laha et al.   PLANT CELL

Inositol pyrophosphates promote tumor growth and metastasis by antagonizing liver kinase B1

(2015) Feng Rao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A novel method for the purification of inositol phosphates from biological samples reveals that no phytate is present in human plasma or urine

(2015) M. S. C. Wilson et al.   Open Biology

Discovery of InsP6-kinases as InsP6-dephosphorylating enzymes provides a new mechanism of cytosolic InsP6degradation driven by the cellular ATP/ADP ratio

(2014) Torsten Wundenberg et al.   BIOCHEMICAL JOURNAL

Synthetic Inositol Phosphate Analogs Reveal that PPIP5K2 Has a Surface-Mounted Substrate Capture Site that Is a Target for Drug Discovery

(2014) Huanchen Wang et al.   CHEMISTRY & BIOLOGY

Inositol Pyrophosphates Mediate the DNA-PK/ATM-p53 Cell Death Pathway by Regulating CK2 Phosphorylation of Tti1/Tel2

(2014) Feng Rao et al.   MOLECULAR CELL

Two inositol hexakisphosphate kinases drive inositol pyrophosphate synthesis in plants

(2014) Mintu Desai et al.   PLANT JOURNAL

Analysis of Dictyostelium discoideum Inositol Pyrophosphate Metabolism by Gel Electrophoresis

(2014) Francesca Pisani et al.   PLoS One

Inositol hexakisphosphate kinase-1 mediates assembly/disassembly of the CRL4–signalosome complex to regulate DNA repair and cell death

(2014) Feng Rao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inositol pyrophosphates mediate the effects of aging on bone marrow mesenchymal stem cells by inhibiting Akt signaling

(2014) Zheng Zhang et al.   Stem Cell Research & Therapy

The Vip1 Inositol Polyphosphate Kinase Family Regulates Polarized Growth and Modulates the Microtubule Cytoskeleton in Fungi

(2014) Jennifer Pöhlmann et al.   PLoS Genetics

Human Genome-Wide RNAi Screen Identifies an Essential Role for Inositol Pyrophosphates in Type-I Interferon Response

(2014) Niyas Kudukkil Pulloor et al.   PLoS Pathogens

PPIP5K1 modulates ligand competition between diphosphoinositol polyphosphates and PtdIns(3,4,5)P3for polyphosphoinositide-binding domains

(2013) Nikhil A. Gokhale et al.   BIOCHEMICAL JOURNAL

Inositol pyrophosphates: between signalling and metabolism

(2013) Miranda S. C. Wilson et al.   BIOCHEMICAL JOURNAL

Inositol hexakisphosphate kinase 1 maintains hemostasis in mice by regulating platelet polyphosphate levels

(2013) S. Ghosh et al.   BLOOD

The enzymes of human diphosphoinositol polyphosphate metabolism

(2013) Mark P. Thomas et al.   FEBS Journal

Understanding inositol pyrophosphate metabolism and function: Kinetic characterization of the DIPPs

(2013) Rajagopal S. Kilari et al.   FEBS LETTERS

Regulation of Inositol Metabolism Is Fine-tuned by Inositol Pyrophosphates inSaccharomyces cerevisiae

(2013) Cunqi Ye et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inositol pyrophosphates regulate JMJD2C-dependent histone demethylation

(2013) A. Burton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inositol Pyrophosphates Regulate Cell Growth and the Environmental Stress Response by Activating the HDAC Rpd3L

(2013) Jeremy Worley et al.   Cell Reports

KCS1deletion inSaccharomyces cerevisiaeleads to a defect in translocation of autophagic proteins and reduces autophagosome formation

(2012) Robert Taylor et al.   Autophagy

Synthesis and biological actions of diphosphoinositol phosphates (inositol pyrophosphates), regulators of cell homeostasis

(2012) Torsten Wundenberg et al.   BIOLOGICAL CHEMISTRY

Inositol Pyrophosphates Modulate S Phase Progression after Pheromone-induced Arrest inSaccharomyces cerevisiae

(2012) Hrvoje Banfic et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inositol Pyrophosphate Synthesis by Inositol Hexakisphosphate Kinase 1 Is Required for Homologous Recombination Repair

(2012) Rathan S. Jadav et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Synthesis and characterization of non-hydrolysable diphosphoinositol polyphosphate messengers

(2012) Mingxuan Wu et al.   Chemical Science

Receptor-dependent compartmentalization of PPIP5K1, a kinase with a cryptic polyphosphoinositide binding domain

(2011) Nikhil A. Gokhale et al.   BIOCHEMICAL JOURNAL

Inositol pyrophosphates in cell death and life

(2011) Michael A. Koldobskiy et al.   CELL CYCLE

Identification of an Evolutionarily Conserved Family of Inorganic Polyphosphate Endopolyphosphatases

(2011) Annalisa Lonetti et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural basis for an inositol pyrophosphate kinase surmounting phosphate crowding

(2011) Huanchen Wang et al.   Nature Chemical Biology

Inositol hexakisphosphate kinase 1 regulates neutrophil function in innate immunity by inhibiting phosphatidylinositol-(3,4,5)-trisphosphate signaling

(2011) Amit Prasad et al.   NATURE IMMUNOLOGY

Influence of Inositol Pyrophosphates on Cellular Energy Dynamics

(2011) Z. Szijgyarto et al.   SCIENCE

Inositol Pyrophosphates as Mammalian Cell Signals

(2011) A. Chakraborty et al.   Science Signaling

Inositol Pyrophosphates Inhibit Akt Signaling, Thereby Regulating Insulin Sensitivity and Weight Gain

(2010) Anutosh Chakraborty et al.   CELL

Inositol hexakisphosphate kinases promote autophagy

(2010) Eiichiro Nagata et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

p53-mediated apoptosis requires inositol hexakisphosphate kinase-2

(2010) M. A. Koldobskiy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inositol pyrophosphates modulate hydrogen peroxide signalling

(2009) Sara Maria Nancy Onnebo et al.   BIOCHEMICAL JOURNAL

Genetic Interaction between Ribosome Biogenesis and Inositol Polyphosphate Metabolism inSaccharomyces cerevisiae

(2009) Chihiro HORIGOME et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Inositol pyrophosphates: structure, enzymology and function

(2009) Christopher John Barker et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Turtles All the Way: Reflections on myo-Inositol: FIGURE 1.

(2009) Bernard W. Agranoff   JOURNAL OF BIOLOGICAL CHEMISTRY

Are inositolpyrophosphates signalling molecules?

(2009) Adam Burton et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Diphosphoinositol Polyphosphates: Metabolic Messengers?

(2009) S. B. Shears   MOLECULAR PHARMACOLOGY

Gene deletion of inositol hexakisphosphate kinase 2 predisposes to aerodigestive tract carcinoma

(2009) B H Morrison et al.   ONCOGENE

The Krebs cycle meets the cell cycle: Mitochondria and the G1-S transition

(2009) T. Finkel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inositol pyrophosphate mediated pyrophosphorylation of AP3B1 regulates HIV-1 Gag release

(2009) Cristina Azevedo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inositol Hexakisphosphate Kinase Products Contain Diphosphate and Triphosphate Groups

(2008) Petra Draškovič et al.   CHEMISTRY & BIOLOGY

Structural Analysis and Detection of Biological Inositol Pyrophosphates Reveal That the Family of VIP/Diphosphoinositol Pentakisphosphate Kinases Are 1/3-Kinases

(2008) Hongying Lin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cellular Energetic Status Supervises the Synthesis of Bis-Diphosphoinositol Tetrakisphosphate Independently of AMP-Activated Protein Kinase

(2008) K. Choi et al.   MOLECULAR PHARMACOLOGY

HSP90 regulates cell survival via inositol hexakisphosphate kinase-2

(2008) A. Chakraborty et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Gene deletion of inositol hexakisphosphate kinase 1 reveals inositol pyrophosphate regulation of insulin secretion, growth, and spermiogenesis

(2008) R. Bhandari et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA