Inositol hexakisphosphate kinase 1 maintains hemostasis in mice by regulating platelet polyphosphate levels

The first comprehensive and quantitative analysis of human platelet protein composition allows the comparative analysis of structural and functional pathways

(2012) J. M. Burkhart et al.   BLOOD

Polyphosphate: an ancient molecule that links platelets, coagulation, and inflammation

(2012) J. H. Morrissey et al.   BLOOD

Inhibition of polyphosphate as a novel strategy for preventing thrombosis and inflammation

(2012) S. A. Smith et al.   BLOOD

Polyphosphate Is a Novel Pro-inflammatory Regulator of Mast Cells and Is Located in Acidocalcisomes

(2012) David Moreno-Sanchez et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Polyphosphate binds to human von Willebrand factor in vivo and modulates its interaction with glycoprotein Ib

(2012) M. MONTILLA et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Carbon's superconducting footprint

(2012) Oskar Vafek   Nature Physics

Nucleic acid scavengers inhibit thrombosis without increasing bleeding

(2012) S. Jain et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Extracellular histones promote thrombin generation through platelet-dependent mechanisms: involvement of platelet TLR2 and TLR4

(2011) F. Semeraro et al.   BLOOD

Polyphosphate is a cofactor for the activation of factor XI by thrombin

(2011) S. H. Choi et al.   BLOOD

Identification of an Evolutionarily Conserved Family of Inorganic Polyphosphate Endopolyphosphatases

(2011) Annalisa Lonetti et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Influence of Inositol Pyrophosphates on Cellular Energy Dynamics

(2011) Z. Szijgyarto et al.   SCIENCE

Inositol Pyrophosphates as Mammalian Cell Signals

(2011) A. Chakraborty et al.   Science Signaling

Inorganic polyphosphates in mitochondria

(2010) T. V. Kulakovskaya et al.   BIOCHEMISTRY-MOSCOW

Polyphosphate exerts differential effects on blood clotting, depending on polymer size

(2010) S. A. Smith et al.   BLOOD

Polyphosphate modifies the fibrin network and down-regulates fibrinolysis by attenuating binding of tPA and plasminogen to fibrin

(2010) N. J. Mutch et al.   BLOOD

Inositol phosphate synthesis and the nuclear processes they affect

(2010) Jessica P Monserrate et al.   CURRENT OPINION IN CELL BIOLOGY

Inorganic Polyphosphate and Energy Metabolism in Mammalian Cells

(2010) Evgeny Pavlov et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hageman factor, platelets and polyphosphates: early history and recent connection

(2010) J. CAEN et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Inorganic Polyphosphate: Essential for Growth and Survival

(2009) Narayana N. Rao et al.   Annual Review of Biochemistry

Platelet Polyphosphates Are Proinflammatory and Procoagulant Mediators In Vivo

(2009) Felicitas Müller et al.   CELL

Inositol pyrophosphates: structure, enzymology and function

(2009) Christopher John Barker et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Characterization of a Selective Inhibitor of Inositol Hexakisphosphate Kinases

(2009) Usha Padmanabhan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Diphosphoinositol Polyphosphates: Metabolic Messengers?

(2009) S. B. Shears   MOLECULAR PHARMACOLOGY

Inositol pyrophosphate mediated pyrophosphorylation of AP3B1 regulates HIV-1 Gag release

(2009) Cristina Azevedo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Catalytic Core of a Membrane-Associated Eukaryotic Polyphosphate Polymerase

(2009) M. Hothorn et al.   SCIENCE

Human Metastasis Regulator Protein H-Prune is a Short-Chain Exopolyphosphatase†

(2008) Marko Tammenkoski et al.   BIOCHEMISTRY

Polyphosphate enhances fibrin clot structure

(2008) S. A. Smith et al.   BLOOD

Polyphosphate as a general procoagulant agent

(2008) S. A. SMITH et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Platelet inorganic polyphosphate decreases in patients with delta storage pool disease

(2008) L. HERNÁNDEZ-RUIZ et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Gene deletion of inositol hexakisphosphate kinase 1 reveals inositol pyrophosphate regulation of insulin secretion, growth, and spermiogenesis

(2008) R. Bhandari et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Eukaryote polyphosphate kinases: is the ‘Kornberg’ complex ubiquitous?

(2008) P HOOLEY et al.   TRENDS IN BIOCHEMICAL SCIENCES