General guidance on exploratory and confirmatory subgroup analysis in late-stage clinical trials

A regression tree approach to identifying subgroups with differential treatment effects

(2015) Wei-Yin Loh et al.   STATISTICS IN MEDICINE

Japanese Guideline on Global Clinical Trials: Statistical Implications and Alternative Criteria for Assessing Consistency

(2015) Kevin J. Carroll et al.   DRUG INFORMATION JOURNAL

Bayesian Assessment of the Influence and Interaction Conditions in Multipopulation Tailoring Clinical Trials

(2014) Brian A. Millen et al.   Journal of Biopharmaceutical Statistics

A Bayesian Approach to Subgroup Identification

(2014) James O. Berger et al.   Journal of Biopharmaceutical Statistics

Reliably Basing Conclusions on Subgroups of Randomized Clinical Trials

(2014) Armin Koch et al.   Journal of Biopharmaceutical Statistics

An Overview of Statistical Planning to Address Subgroups in Confirmatory Clinical Trials

(2014) Gary G. Koch et al.   Journal of Biopharmaceutical Statistics

Adaptive Designs for Confirmatory Clinical Trials with Subgroup Selection

(2014) Nigel Stallard et al.   Journal of Biopharmaceutical Statistics

A Regulatory Perspective on Essential Considerations in Design and Analysis of Subgroups When Correctly Classified

(2014) Sue-Jane Wang et al.   Journal of Biopharmaceutical Statistics

Multipopulation Tailoring Clinical Trials

(2014) Brian A. Millen et al.   Therapeutic Innovation & Regulatory Science

Estimating treatment effect heterogeneity in randomized program evaluation

(2013) Kosuke Imai et al.   Annals of Applied Statistics

Multiplicity considerations for subgroup analysis subject to consistency constraint

(2013) Mohamed Alosh et al.   BIOMETRICAL JOURNAL

Interaction of treatment with a continuous variable: simulation study of significance level for several methods of analysis

(2013) Patrick Royston et al.   STATISTICS IN MEDICINE

Traditional multiplicity adjustment methods in clinical trials

(2013) Alex Dmitrienko et al.   STATISTICS IN MEDICINE

A Robust Method for Estimating Optimal Treatment Regimes

(2012) Baqun Zhang et al.   BIOMETRICS

Randomized Phase II Trial Designs With Biomarkers

(2012) Boris Freidlin et al.   JOURNAL OF CLINICAL ONCOLOGY

Estimating Individualized Treatment Rules Using Outcome Weighted Learning

(2012) Yingqi Zhao et al.   JOURNAL OF THE AMERICAN STATISTICAL ASSOCIATION

Key multiplicity issues in clinical drug development

(2012) Alex Dmitrienko et al.   STATISTICS IN MEDICINE

A conditional error function approach for subgroup selection in adaptive clinical trials

(2012) T. Friede et al.   STATISTICS IN MEDICINE

Bayesian models for subgroup analysis in clinical trials

(2011) Hayley E Jones et al.   Clinical Trials

Variable Selection for Qualitative Interactions in Personalized Medicine While Controlling the Family-Wise Error Rate

(2011) Lacey Gunter et al.   Journal of Biopharmaceutical Statistics

Subgroup identification from randomized clinical trial data

(2011) Jared C. Foster et al.   STATISTICS IN MEDICINE

Stability selection

(2010) Nicolai Meinshausen et al.   JOURNAL OF THE ROYAL STATISTICAL SOCIETY SERIES B-STATISTICAL METHODOLOGY

An adaptive seamless phase II/III design for oncology trials with subpopulation selection using correlated survival endpoints†

(2010) Martin Jenkins et al.   PHARMACEUTICAL STATISTICS

Confirmatory adaptive designs with Bayesian decision tools for a targeted therapy in oncology

(2009) Werner Brannath et al.   STATISTICS IN MEDICINE

A small sample study of the STEPP approach to assessing treatment-covariate interactions in survival data

(2009) Marco Bonetti et al.   STATISTICS IN MEDICINE

A flexible strategy for testing subgroups and overall population

(2008) Mohamed Alosh et al.   STATISTICS IN MEDICINE