Chemistry enters nucleic acids biology: Enzymatic mechanisms of RNA modification

Cysteine Methylation Controls Radical Generation in the Cfr Radical AdoMet rRNA Methyltransferase

(2013) Martin R. Challand et al.   PLoS One

Unique 2′-O-Methylation by Hen1 in Eukaryotic RNA Interference and Bacterial RNA Repair

(2012) Raven H. Huang   BIOCHEMISTRY

Enzymology of tRNA modification in the bacterial MnmEG pathway

(2012) M.-Eugenia Armengod et al.   BIOCHIMIE

Functional Analysis of Bacillus subtilis Genes Involved in the Biosynthesis of 4-Thiouridine in tRNA

(2012) Lauren J. Rajakovich et al.   JOURNAL OF BACTERIOLOGY

Biosynthesis of 4-Thiouridine in tRNA in the Methanogenic ArchaeonMethanococcus maripaludis

(2012) Yuchen Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Radical SAM enzymes in methylation and methylthiolation

(2012) Rachel U. Hutcheson et al.   Metallomics

MODOMICS: a database of RNA modification pathways—2013 update

(2012) Magdalena A. Machnicka et al.   NUCLEIC ACIDS RESEARCH

Structural Insights into Radical Generation by the Radical SAM Superfamily

(2011) Jessica L. Vey et al.   CHEMICAL REVIEWS

Insights into Folate/FAD-dependent tRNA Methyltransferase Mechanism

(2011) Djemel Hamdane et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Products of 5-Fluorouridine by the Action of the Pseudouridine Synthase TruB Disfavor One Mechanism and Suggest Another

(2011) Edward J. Miracco et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Pre-steady-state kinetic analysis of the three Escherichia coli pseudouridine synthases TruB, TruA, and RluA reveals uniformly slow catalysis

(2011) J. R. Wright et al.   RNA

A Radically Different Mechanism for S-Adenosylmethionine-Dependent Methyltransferases

(2011) T. L. Grove et al.   SCIENCE

Mechanism-Based Strategies for Trapping and Crystallizing Complexes of RNA-Modifying Enzymes

(2011) Amandine Guelorget et al.   STRUCTURE

Crystal Structure and Functional Analysis of the SARS-Coronavirus RNA Cap 2′-O-Methyltransferase nsp10/nsp16 Complex

(2011) Etienne Decroly et al.   PLoS Pathogens

RNA nucleotide methylation

(2011) Yuri Motorin et al.   Wiley Interdisciplinary Reviews-RNA

tRNA Stabilization by Modified Nucleotides

(2010) Yuri Motorin et al.   BIOCHEMISTRY

Identification of Eukaryotic and Prokaryotic Methylthiotransferase for Biosynthesis of 2-Methylthio-N6-threonylcarbamoyladenosine in tRNA

(2010) Simon Arragain et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Glycosidic Bond Conformation Preference Plays a Pivotal Role in Catalysis of RNA Pseudouridylation: A Combined Simulation and Structural Study

(2010) Jing Zhou et al.   JOURNAL OF MOLECULAR BIOLOGY

Mechanism of N-methylation by the tRNA m1G37 methyltransferase Trm5

(2010) T. Christian et al.   RNA

RNA Processing and Export

(2010) S. Hocine et al.   Cold Spring Harbor Perspectives in Biology

Identification of the Rate-Determining Step of tRNA-Guanine Transglycosylase fromEscherichia coli

(2009) George A. Garcia et al.   BIOCHEMISTRY

Stereochemical mechanisms of tRNA methyltransferases

(2009) Ya-Ming Hou et al.   FEBS LETTERS

5-methylcytosine in RNA: detection, enzymatic formation and biological functions

(2009) Yuri Motorin et al.   NUCLEIC ACIDS RESEARCH

Structural and biochemical insights into 2'-O-methylation at the 3'-terminal nucleotide of RNA by Hen1

(2009) C. Mui Chan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Atomic structure of a folate/FAD-dependent tRNA T54 methyltransferase

(2009) H. Nishimasu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Conserved Cysteine Residues of GidA Are Essential for Biogenesis of 5-Carboxymethylaminomethyluridine at tRNA Anticodon

(2009) Takuo Osawa et al.   STRUCTURE

Direct Evidence that ThiI is an ATP Pyrophosphatase for the Adenylation of Uridine in 4-Thiouridine Biosynthesis

(2008) Delin You et al.   CHEMBIOCHEM

Crystal Structures of the Conserved tRNA-Modifying Enzyme GidA: Implications for Its Interaction with MnmE and Substrate

(2008) S. Meyer et al.   JOURNAL OF MOLECULAR BIOLOGY

Crystallographic snapshots of eukaryotic dimethylallyltransferase acting on tRNA: Insight into tRNA recognition and reaction mechanism

(2008) C. Zhou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mutational analysis of vaccinia virus mRNA cap (guanine-N7) methyltransferase reveals essential contributions of the N-terminal peptide that closes over the active site

(2008) S. Zheng et al.   RNA