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Title
The structural mechanisms that underpin mitotic kinase activation
Authors
Keywords
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Journal
BIOCHEMICAL SOCIETY TRANSACTIONS
Volume 41, Issue 4, Pages 1037-1041
Publisher
Portland Press Ltd.
Online
2013-07-18
DOI
10.1042/bst20130066
References
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Note: Only part of the references are listed.- The Structural Basis for Control of Eukaryotic Protein Kinases
- (2012) Jane A. Endicott et al. Annual Review of Biochemistry
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- Cell cycle regulation by the NEK family of protein kinases
- (2012) A. M. Fry et al. JOURNAL OF CELL SCIENCE
- On the molecular mechanisms of mitotic kinase activation
- (2012) R. Bayliss et al. Open Biology
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- Nek9, Nek6, Nek7 and the separation of centrosomes
- (2011) Sara Sdelci et al. CELL CYCLE
- Activation of Aurora-A Kinase by Protein Partner Binding and Phosphorylation Are Independent and Synergistic
- (2011) Charlotte A. Dodson et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Benzimidazole Inhibitors Induce a DFG-Out Conformation of Never in Mitosis Gene A-Related Kinase 2 (Nek2) without Binding to the Back Pocket and Reveal a Nonlinear Structure−Activity Relationship
- (2011) Savade Solanki et al. JOURNAL OF MEDICINAL CHEMISTRY
- Drug-Resistant Aurora A Mutants for Cellular Target Validation of the Small Molecule Kinase Inhibitors MLN8054 and MLN8237
- (2010) Dominic A. Sloane et al. ACS Chemical Biology
- Crystal structure of an Aurora-A mutant that mimics Aurora-B bound to MLN8054: insights into selectivity and drug design
- (2010) Charlotte A. Dodson et al. BIOCHEMICAL JOURNAL
- Protein phosphatase 6 regulates mitotic spindle formation by controlling the T-loop phosphorylation state of Aurora A bound to its activator TPX2
- (2010) Kang Zeng et al. JOURNAL OF CELL BIOLOGY
- Aminopyrazine Inhibitors Binding to an Unusual Inactive Conformation of the Mitotic Kinase Nek2: SAR and Structural Characterization
- (2010) Daniel K. Whelligan et al. JOURNAL OF MEDICINAL CHEMISTRY
- Quantitative Phosphoproteomics Reveals Widespread Full Phosphorylation Site Occupancy During Mitosis
- (2010) J. V. Olsen et al. Science Signaling
- Discovery and Exploitation of Inhibitor-resistant Aurora and Polo Kinase Mutants for the Analysis of Mitotic Networks
- (2009) Paul J. Scutt et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The Nek6 and Nek7 Protein Kinases Are Required for Robust Mitotic Spindle Formation and Cytokinesis
- (2009) L. O'Regan et al. MOLECULAR AND CELLULAR BIOLOGY
- An Autoinhibitory Tyrosine Motif in the Cell-Cycle-Regulated Nek7 Kinase Is Released through Binding of Nek9
- (2009) Mark W. Richards et al. MOLECULAR CELL
- Insights into the Conformational Variability and Regulation of Human Nek2 Kinase
- (2008) Isaac Westwood et al. JOURNAL OF MOLECULAR BIOLOGY
- A helix scaffold for the assembly of active protein kinases
- (2008) A. P. Kornev et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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