Benzimidazole Inhibitors Induce a DFG-Out Conformation of Never in Mitosis Gene A-Related Kinase 2 (Nek2) without Binding to the Back Pocket and Reveal a Nonlinear Structure−Activity Relationship

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Title
Benzimidazole Inhibitors Induce a DFG-Out Conformation of Never in Mitosis Gene A-Related Kinase 2 (Nek2) without Binding to the Back Pocket and Reveal a Nonlinear Structure−Activity Relationship
Authors
Keywords
-
Journal
JOURNAL OF MEDICINAL CHEMISTRY
Volume 54, Issue 6, Pages 1626-1639
Publisher
American Chemical Society (ACS)
Online
2011-03-03
DOI
10.1021/jm1011726

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