Functional and Structural Divergence in Human TRPV1 Channel Subunits by Oxidative Cysteine Modification

Targeting the Transient Receptor Potential Vanilloid Type 1 (TRPV1) Assembly Domain Attenuates Inflammation-induced Hypersensitivity

(2014) Robyn Flynn et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Extracellular disulfide bridges stabilize TRPC5 dimerization, trafficking, and activity

(2014) Chansik Hong et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Redox Regulation of Transient Receptor Potential Channels

(2013) Daisuke Kozai et al.   ANTIOXIDANTS & REDOX SIGNALING

Thiol-blocking electrophiles interfere with labeling and detection of protein sulfenic acids

(2013) Julie A. Reisz et al.   FEBS Journal

N-terminus oligomerization regulates the function of cardiac ryanodine receptors

(2013) S. Zissimopoulos et al.   JOURNAL OF CELL SCIENCE

Structure of the TRPV1 ion channel determined by electron cryo-microscopy

(2013) Maofu Liao et al.   NATURE

Role of TRPA1 and TRPV1 in the ROS-dependent sensory irritation of superior laryngeal capsaicin-sensitive afferents by cigarette smoke in anesthetized rats

(2013) Bi-Yu Liu et al.   PULMONARY PHARMACOLOGY & THERAPEUTICS

Redox signal-mediated sensitization of transient receptor potential melastatin 2 (TRPM2) to temperature affects macrophage functions

(2012) M. Kashio et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Presenting your structures: theCCP4mgmolecular-graphics software

(2011) S. McNicholas et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

C-terminal Dimerization Activates the Nociceptive Transduction Channel Transient Receptor Potential Vanilloid 1

(2011) Shu Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification ofin VivoDisulfide Conformation of TRPA1 Ion Channel

(2011) Liwen Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Endocannabinoids Modulate Human Epidermal Keratinocyte Proliferation and Survival via the Sequential Engagement of Cannabinoid Receptor-1 and Transient Receptor Potential Vanilloid-1

(2011) Balázs I. Tóth et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

TRPA1 underlies a sensing mechanism for O2

(2011) Nobuaki Takahashi et al.   Nature Chemical Biology

Molecular characterization of TRPA1 channel activation by cysteine-reactive inflammatory mediators

(2010) Nobuaki Takahashi et al.   Channels

Oxidative challenges sensitize the capsaicin receptor by covalent cysteine modification

(2009) H.-h. Chuang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Quantifying the global cellular thiol-disulfide status

(2009) R. E. Hansen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Crystal Structure of the Eukaryotic Strong Inward-Rectifier K+ Channel Kir2.2 at 3.1 A Resolution

(2009) X. Tao et al.   SCIENCE

Heat-induced MMP-1 expression is mediated by TRPV1 through PKCαsignaling in HaCaT cells

(2008) Young Mee Lee et al.   EXPERIMENTAL DERMATOLOGY

Cyclooxygenases 1 and 2 contribute to peroxynitrite-mediated inflammatory pain hypersensitivity

(2008) Michael M. Ndengele et al.   FASEB JOURNAL

TRPA1 is a major oxidant sensor in murine airway sensory neurons

(2008) Bret F. Bessac et al.   JOURNAL OF CLINICAL INVESTIGATION

Transient Receptor Potential A1 Is a Sensory Receptor for Multiple Products of Oxidative Stress

(2008) D. A. Andersson et al.   JOURNAL OF NEUROSCIENCE

TRPC channel activation by extracellular thioredoxin

(2008) Shang-Zhong Xu et al.   NATURE

Transient receptor potential channels: targeting pain at the source

(2008) Ardem Patapoutian et al.   NATURE REVIEWS DRUG DISCOVERY

Hydrogen peroxide is a novel mediator of inflammatory hyperalgesia, acting via transient receptor potential vanilloid 1-dependent and independent mechanisms

(2008) Julie Elizabeth Keeble et al.   PAIN