Targeting the Transient Receptor Potential Vanilloid Type 1 (TRPV1) Assembly Domain Attenuates Inflammation-induced Hypersensitivity

Calcium-Permeable Ion Channels in Pain Signaling

(2014) Emmanuel Bourinet et al.   PHYSIOLOGICAL REVIEWS

TRP Channels and Pain

(2013) David Julius   Annual Review of Cell and Developmental Biology

Coarse Architecture of the Transient Receptor Potential Vanilloid 1 (TRPV1) Ion Channel Determined by Fluorescence Resonance Energy Transfer

(2013) Víctor De-la-Rosa et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Disrupting Sensitization of Transient Receptor Potential Vanilloid Subtype 1 Inhibits Inflammatory Hyperalgesia

(2013) M. J. M. Fischer et al.   JOURNAL OF NEUROSCIENCE

TRPV1 structures in distinct conformations reveal activation mechanisms

(2013) Erhu Cao et al.   NATURE

Structure of the TRPV1 ion channel determined by electron cryo-microscopy

(2013) Maofu Liao et al.   NATURE

Osteoarthritis pain mechanisms: basic studies in animal models

(2013) R.-X. Zhang et al.   OSTEOARTHRITIS AND CARTILAGE

Pain-like behaviour and spinal changes in the monosodium iodoacetate model of osteoarthritis in C57Bl/6 mice

(2012) A. C. Ogbonna et al.   EUROPEAN JOURNAL OF PAIN

Intact Microtubules Preserve Transient Receptor Potential Vanilloid 1 (TRPV1) Functionality through Receptor Binding

(2012) Barbara Storti et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

TRPV1 in GABAergic Interneurons Mediates Neuropathic Mechanical Allodynia and Disinhibition of the Nociceptive Circuitry in the Spinal Cord

(2012) Yong Ho Kim et al.   NEURON

Afferent drive elicits ongoing pain in a model of advanced osteoarthritis

(2012) Alec Okun et al.   PAIN

Membrane-tethered peptides patterned after the TRP domain (TRPducins) selectively inhibit TRPV1 channel activity

(2011) Pierluigi Valente et al.   FASEB JOURNAL

C-terminal Dimerization Activates the Nociceptive Transduction Channel Transient Receptor Potential Vanilloid 1

(2011) Shu Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification of a Tetrameric Assembly Domain in the C Terminus of Heat-activated TRPV1 Channels

(2011) Feng Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Transient receptor potential channels as therapeutic targets

(2011) Magdalene M. Moran et al.   NATURE REVIEWS DRUG DISCOVERY

TRPV1-related modulation of spinal neuronal activity and behavior in a rat model of osteoarthritic pain

(2010) Katharine L. Chu et al.   BRAIN RESEARCH

A Bivalent Tarantula Toxin Activates the Capsaicin Receptor, TRPV1, by Targeting the Outer Pore Domain

(2010) Christopher J. Bohlen et al.   CELL

Pre-treatment with capsaicin in a rat osteoarthritis model reduces the symptoms of pain and bone damage induced by monosodium iodoacetate

(2010) Karel-Martijn Kalff et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

The Cavβ subunit prevents RFP2-mediated ubiquitination and proteasomal degradation of L-type channels

(2010) Christophe Altier et al.   NATURE NEUROSCIENCE

A-995662 [(R)-8-(4-methyl-5-(4-(trifluoromethyl)phenyl)oxazol-2-ylamino)-1,2,3,4-tetrahydronaphthalen-2-ol], a novel, selective TRPV1 receptor antagonist, reduces spinal release of glutamate and CGRP in a rat knee joint pain model

(2010) Pamela S. Puttfarcken et al.   PAIN

An efficient one-step site-directed deletion, insertion, single and multiple-site plasmid mutagenesis protocol

(2009) Huanting Liu et al.   BMC BIOTECHNOLOGY

Cellular and Molecular Mechanisms of Pain

(2009) Allan I. Basbaum et al.   CELL

Behavioural and Electrophysiological Characterisation of Experimentally Induced Osteoarthritis and Neuropathy in C57Bl/6 Mice

(2009) Victoria L Harvey et al.   Molecular Pain

A-kinase anchoring protein 150 controls protein kinase C-mediated phosphorylation and sensitization of TRPV1

(2009) Nathaniel A. Jeske et al.   PAIN

Repeated dosing of ABT-102, a potent and selective TRPV1 antagonist, enhances TRPV1-mediated analgesic activity in rodents, but attenuates antagonist-induced hyperthermia

(2009) Prisca Honore et al.   PAIN

Differential analgesic effects of morphine and gabapentin on behavioural measures of pain and disability in a model of osteoarthritis pain in rats

(2008) Jean Laurent Vonsy et al.   EUROPEAN JOURNAL OF PAIN

Protein Kinase A Anchoring via AKAP150 Is Essential for TRPV1 Modulation by Forskolin and Prostaglandin E2 in Mouse Sensory Neurons

(2008) K. Schnizler et al.   JOURNAL OF NEUROSCIENCE

Proinflammatory Mediators Modulate the Heat-Activated Ion Channel TRPV1 via the Scaffolding Protein AKAP79/150

(2008) Xuming Zhang et al.   NEURON