Phosphorylation of the Hippo Pathway Component AMOTL2 by the mTORC2 Kinase Promotes YAP Signaling, Resulting in Enhanced Glioblastoma Growth and Invasiveness

Role of Yes-associated protein 1 in gliomas: pathologic and therapeutic aspects

(2015) Yong-Chang Liu et al.   TUMOR BIOLOGY

The Neurofibromatosis 2 Tumor Suppressor Gene Product, Merlin, Regulates Human Meningioma Cell Growth by Signaling through YAP

(2015) Katherine Striedinger et al.   NEOPLASIA

The Hippo signaling pathway in stem cell biology and cancer

(2014) J.-S. Mo et al.   EMBO REPORTS

Regulation of YAP by mTOR and autophagy reveals a therapeutic target of tuberous sclerosis complex

(2014) Ning Liang et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Making new contacts: the mTOR network in metabolism and signalling crosstalk

(2014) Mitsugu Shimobayashi et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Overcoming resistance to rapalogs in gliomas by combinatory therapies

(2013) Michal Grzmil et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

mTOR in aging, metabolism, and cancer

(2013) Marion Cornu et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Nutrient regulation of the mTOR Complex 1 signaling pathway

(2013) Sang Gyun Kim et al.   MOLECULES AND CELLS

Regulation of the Hippo-YAP Pathway by G-Protein-Coupled Receptor Signaling

(2012) Fa-Xing Yu et al.   CELL

mTOR Signaling in Growth Control and Disease

(2012) Mathieu Laplante et al.   CELL

Identification of Serum-Derived Sphingosine-1-Phosphate as a Small Molecule Regulator of YAP

(2012) Eric Miller et al.   CHEMISTRY & BIOLOGY

Genetic and pharmacological disruption of the TEAD-YAP complex suppresses the oncogenic activity of YAP

(2012) Y. Liu-Chittenden et al.   GENES & DEVELOPMENT

Emerging insights into the molecular and cellular basis of glioblastoma

(2012) G. P. Dunn et al.   GENES & DEVELOPMENT

Hippo–YAP and mTOR pathways collaborate to regulate organ size

(2012) Alfred Csibi et al.   NATURE CELL BIOLOGY

YAP mediates crosstalk between the Hippo and PI(3)K–TOR pathways by suppressing PTEN via miR-29

(2012) Karen Tumaneng et al.   NATURE CELL BIOLOGY

Conditional Astroglial Rictor Overexpression Induces Malignant Glioma in Mice

(2012) Tariq Bashir et al.   PLoS One

The YAP and TAZ transcription co-activators: Key downstream effectors of the mammalian Hippo pathway

(2012) Wanjin Hong et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Glioblastoma: From Molecular Pathology to Targeted Treatment

(2011) Timothy F. Cloughesy et al.   Annual Review of Pathology-Mechanisms of Disease

Protor-2 interacts with tristetraprolin to regulate mRNA stability during stress

(2011) Brent Holmes et al.   CELLULAR SIGNALLING

Angiomotin is a novel Hippo pathway component that inhibits YAP oncoprotein

(2011) B. Zhao et al.   GENES & DEVELOPMENT

Hippo Pathway-independent Restriction of TAZ and YAP by Angiomotin

(2011) Siew Wee Chan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Yes-Associated Protein 1 Is Widely Expressed in Human Brain Tumors and Promotes Glioblastoma Growth

(2011) Brent A. Orr et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Angiomotin family proteins are novel activators of the LATS2 kinase tumor suppressor

(2011) Murugan Paramasivam et al.   MOLECULAR BIOLOGY OF THE CELL

Inhibition of SAPK2/p38 Enhances Sensitivity to mTORC1 Inhibition by Blocking IRES-Mediated Translation Initiation in Glioblastoma

(2011) C. Cloninger et al.   MOLECULAR CANCER THERAPEUTICS

Molecular pathology in adult high-grade gliomas: from molecular diagnostics to target therapies

(2011) K. Masui et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Oncogenic YAP promotes radioresistance and genomic instability in medulloblastoma through IGF2-mediated Akt activation

(2011) A Fernandez-L et al.   ONCOGENE

The mTOR-Regulated Phosphoproteome Reveals a Mechanism of mTORC1-Mediated Inhibition of Growth Factor Signaling

(2011) P. P. Hsu et al.   SCIENCE

Oncogenic EGFR Signaling Activates an mTORC2-NF- B Pathway That Promotes Chemotherapy Resistance

(2011) K. Tanaka et al.   Cancer Discovery

The Merlin/NF2 Tumor Suppressor Functions through the YAP Oncoprotein to Regulate Tissue Homeostasis in Mammals

(2010) Nailing Zhang et al.   DEVELOPMENTAL CELL

Angiomotin-like Proteins Associate with and Negatively Regulate YAP1

(2010) Wenqi Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

mTOR: from growth signal integration to cancer, diabetes and ageing

(2010) Roberto Zoncu et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Deciphering Protein Kinase Specificity Through Large-Scale Analysis of Yeast Phosphorylation Site Motifs

(2010) J. Mok et al.   Science Signaling

TOR complex 2: a signaling pathway of its own

(2009) Nadine Cybulski et al.   TRENDS IN BIOCHEMICAL SCIENCES

Merlin Is a Potent Inhibitor of Glioma Growth

(2008) Y.-K. I. Lau et al.   CANCER RESEARCH

Heterogeneous Nuclear Ribonucleoprotein A1 Regulates Cyclin D1 and c-mycInternal Ribosome Entry Site Function through Akt Signaling

(2008) Oak D. Jo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY