Eps8 controls dendritic spine density and synaptic plasticity through its actin-capping activity

Activity-Dependent Spine Morphogenesis: A Role for the Actin-Capping Protein Eps8

(2013) E. Stamatakou et al.   JOURNAL OF NEUROSCIENCE

Altered Balance of Proteolytic Isoforms of Pro-Brain-Derived Neurotrophic Factor in Autism

(2012) Kristine L.P. Garcia et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Cracking Down on Inhibition: Selective Removal of GABAergic Interneurons from Hippocampal Networks

(2012) F. Antonucci et al.   JOURNAL OF NEUROSCIENCE

Differential roles of EPS8 in carcinogenesis: Loss of protein expression in a subset of colorectal carcinoma and adenoma

(2012) Wael M Abdel-Rahman   WORLD JOURNAL OF GASTROENTEROLOGY

Pharmacologic Rescue of Impaired Cognitive Flexibility, Social Deficits, Increased Aggression, and Seizure Susceptibility in Oxytocin Receptor Null Mice: A Neurobehavioral Model of Autism

(2011) Mariaelvina Sala et al.   BIOLOGICAL PSYCHIATRY

PICK1 inhibition of the Arp2/3 complex controls dendritic spine size and synaptic plasticity

(2011) Yasuko Nakamura et al.   EMBO JOURNAL

The Signaling Adaptor Eps8 Is an Essential Actin Capping Protein for Dendritic Cell Migration

(2011) Emanuela Frittoli et al.   IMMUNITY

Nerve growth factor promoter activity revealed in mice expressing enhanced green fluorescent protein

(2011) Michael D. Kawaja et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Actin Capping Protein Is Required for Dendritic Spine Development and Synapse Formation

(2011) Y. Fan et al.   JOURNAL OF NEUROSCIENCE

Dendritic spine pathology in neuropsychiatric disorders

(2011) Peter Penzes et al.   NATURE NEUROSCIENCE

Eps8 Regulates Hair Bundle Length and Functional Maturation of Mammalian Auditory Hair Cells

(2011) Valeria Zampini et al.   PLOS BIOLOGY

The Eps8/IRSp53/VASP Network Differentially Controls Actin Capping and Bundling in Filopodia Formation

(2011) Federico Vaggi et al.   PLoS Computational Biology

Synapse Pathology in Psychiatric and Neurologic Disease

(2010) Myrrhe van Spronsen et al.   Current Neurology and Neuroscience Reports

Eps8 is recruited to lysosomes and subjected to chaperone-mediated autophagy in cancer cells

(2010) Thilo Welsch et al.   EXPERIMENTAL CELL RESEARCH

Activity-dependent localization in spines of the F-actin capping protein CapZ screened in a rat model of dementia

(2010) Takuma Kitanishi et al.   GENES TO CELLS

Actin in dendritic spines: connecting dynamics to function

(2010) Pirta Hotulainen et al.   JOURNAL OF CELL BIOLOGY

Long-Term Potentiation-Dependent Spine Enlargement Requires Synaptic Ca2+-Permeable AMPA Receptors Recruited by CaM-Kinase I

(2010) D. A. Fortin et al.   JOURNAL OF NEUROSCIENCE

Regulation of the Postsynaptic Cytoskeleton: Roles in Development, Plasticity, and Disorders

(2010) T. Svitkina et al.   JOURNAL OF NEUROSCIENCE

SAP102 Is a Highly Mobile MAGUK in Spines

(2010) C. Y. Zheng et al.   JOURNAL OF NEUROSCIENCE

Functional impact of global rare copy number variation in autism spectrum disorders

(2010) Dalila Pinto et al.   NATURE

Loss of the Actin Remodeler Eps8 Causes Intestinal Defects and Improved Metabolic Status in Mice

(2010) Arianna Tocchetti et al.   PLoS One

Key role for gene dosage and synaptic homeostasis in autism spectrum disorders

(2010) Roberto Toro et al.   TRENDS IN GENETICS

Molecular Basis for the Dual Function of Eps8 on Actin Dynamics: Bundling and Capping

(2010) Maud Hertzog et al.   PLOS BIOLOGY

Dendritic Spine Dynamics

(2009) D. Harshad Bhatt et al.   Annual Review of Physiology

Increased dendritic spine densities on cortical projection neurons in autism spectrum disorders

(2009) Jeffrey J. Hutsler et al.   BRAIN RESEARCH

Dendritic spine formation and stabilization

(2009) Yoshihiro Yoshihara et al.   CURRENT OPINION IN NEUROBIOLOGY

A synaptic trek to autism

(2009) Thomas Bourgeron   CURRENT OPINION IN NEUROBIOLOGY

Expression of mutant β2 nicotinic receptors during development is crucial for epileptogenesis

(2009) Irene Manfredi et al.   HUMAN MOLECULAR GENETICS

Defining mechanisms of actin polymerization and depolymerization during dendritic spine morphogenesis

(2009) Pirta Hotulainen et al.   JOURNAL OF CELL BIOLOGY

Modulation of dendritic spine development and plasticity by BDNF and vesicular trafficking: fundamental roles in neurodevelopmental disorders associated with mental retardation and autism

(2009) Christopher A. Chapleau et al.   Journal of Neurodevelopmental Disorders

Interfering with the Actin Network and Its Effect on Long-Term Potentiation and Synaptic Tagging in Hippocampal CA1 Neurons in Slices In Vitro

(2009) B. Ramachandran et al.   JOURNAL OF NEUROSCIENCE

Exchange and Redistribution Dynamics of the Cytoskeleton of the Active Zone Molecule Bassoon

(2009) S. Tsuriel et al.   JOURNAL OF NEUROSCIENCE

Molecular Architecture of Synaptic Actin Cytoskeleton in Hippocampal Neurons Reveals a Mechanism of Dendritic Spine Morphogenesis

(2009) Farida Korobova et al.   MOLECULAR BIOLOGY OF THE CELL

Multiple functions of precursor BDNF to CNS neurons: negative regulation of neurite growth, spine formation and cell survival

(2009) Hisatsugu Koshimizu et al.   Molecular Brain

Capzb2 Interacts with β-Tubulin to Regulate Growth Cone Morphology and Neurite Outgrowth

(2009) David A. Davis et al.   PLOS BIOLOGY

Eps8 Regulates Axonal Filopodia in Hippocampal Neurons in Response to Brain-Derived Neurotrophic Factor (BDNF)

(2009) Elisabetta Menna et al.   PLOS BIOLOGY

The Autistic Neuron: Troubled Translation?

(2008) Raymond J. Kelleher et al.   CELL

Capping Protein Increases the Rate of Actin-Based Motility by Promoting Filament Nucleation by the Arp2/3 Complex

(2008) Orkun Akin et al.   CELL

Distinct Role of Long 3′ UTR BDNF mRNA in Spine Morphology and Synaptic Plasticity in Hippocampal Neurons

(2008) Juan Ji An et al.   CELL

N-WASP and the Arp2/3 Complex Are Critical Regulators of Actin in the Development of Dendritic Spines and Synapses

(2008) Adam M. Wegner et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Organization of the Arp2/3 Complex in Hippocampal Spines

(2008) B. Racz et al.   JOURNAL OF NEUROSCIENCE

Arp2/3 Complex Is Important for Filopodia Formation, Growth Cone Motility, and Neuritogenesis in Neuronal Cells

(2008) Farida Korobova et al.   MOLECULAR BIOLOGY OF THE CELL

Actin in action: the interplay between the actin cytoskeleton and synaptic efficacy

(2008) Lorenzo A. Cingolani et al.   NATURE REVIEWS NEUROSCIENCE

The Subspine Organization of Actin Fibers Regulates the Structure and Plasticity of Dendritic Spines

(2008) Naoki Honkura et al.   NEURON

Protein Synthesis and Neurotrophin-Dependent Structural Plasticity of Single Dendritic Spines

(2008) J.-i. Tanaka et al.   SCIENCE

Cadherins and catenins at synapses: roles in synaptogenesis and synaptic plasticity

(2008) Jyothi Arikkath et al.   TRENDS IN NEUROSCIENCES

Progression of multiple behavioral deficits with various ages of onset in a murine model of Hurler syndrome

(2007) Dao Pan et al.   BRAIN RESEARCH